Phenotypical and Functional Characteristics of Human Regulatory T Cells during Ex Vivo Maturation from CD4+ T Lymphocytes

Regulatory T cells (Tregs) participate in the negative regulation of inflammatory reactions by suppressing effector cells. In a number of autoimmune disorders, the suppressive function and/or the number of Tregs is compromised. The lack of active functioning Tregs can be restored with adoptive trans...

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Bibliographic Details
Published in:	Applied sciences Vol. 11; no. 13; p. 5776
Main Authors:	Blinova, Varvara G., Novachly, Natalia S., Gippius, Sofya N., Hilal, Abdullah, Gladilina, Yulia A., Eliseeva, Daria D., Zhdanov, Dmitry D.
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 01.07.2021
Subjects:	alternative splicing Antibodies Antigens Autoimmune diseases Cell cycle DNA methylation Flow cytometry Gene expression Lymphocytes proliferation markers Proteins Senescence Software T cell receptors T cell-specific demethylation region Telomerase Tregs expansion Austria United States > US Germany Russia
ISSN:	2076-3417, 2076-3417
Online Access:	Get full text
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