CD69 flow cytometry to complement interferon‐γ release assay for active tuberculosis

Background The interferon‐γ (IFN‐γ) release assay (IGRA) is widely used to diagnose tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb). However, indeterminate IGRA results due to “high Nil” or “low PHA” responses limit its clinical utility. We developed a novel assay using CD69 flow cytome...

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Veröffentlicht in:	Cytometry. Part B, Clinical cytometry Jg. 102; H. 6; S. 471 - 486
Hauptverfasser:	Kim, Yoonjung, Han, Man‐Hoon, Kim, Shin‐Woo, Won, Dong Il
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken, USA John Wiley & Sons, Inc 01.11.2022 Wiley Subscription Services, Inc
Schlagworte:	Antigens Antigens, Bacterial Assaying CD3 antigen CD4 antigen CD69 CD69 antigen CD8 antigen Centrifugation Complement Diagnostic systems Flow Cytometry Humans Interferon Interferon-gamma Release Tests - methods interferon‐γ release assay Latent Tuberculosis Lymphocytes Lymphocytes T Mycobacterium tuberculosis Tuberculosis Tuberculosis - diagnosis Tubes interferon-γ release assay flow cytometry CD69 tuberculosis
ISSN:	1552-4949, 1552-4957, 1552-4957
Online-Zugang:	Volltext
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