Computational study of p53 regulation via the chemical master equation

A stochastic model of cellular p53 regulation was established in Leenders, and Tuszynski (2013 Front. Oncol. 3 1-16) to study the interactions of p53 with MDM2 proteins, where the stochastic analysis was done using a Monte Carlo approach. We revisit that model here using an alternative scheme, which...

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Vydané v:	Physical biology Ročník 13; číslo 3; s. 035001
Hlavní autori:	Vo, Huy D, Sidje, Roger B
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 29.04.2016
Predmet:	Algorithms Computer Simulation Models, Chemical Proto-Oncogene Proteins c-mdm2 - chemistry Proto-Oncogene Proteins c-mdm2 - metabolism Stochastic Processes Tumor Suppressor Protein p53 - chemistry Tumor Suppressor Protein p53 - metabolism
ISSN:	1478-3975, 1478-3975
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