Discovery solubility measurement and assessment of small molecules with drug development in mind

•Seamless solubility understanding requires discovery-development collaboration.•Gold standard methods in drug development map solubility of drug candidates.•Drug development solubility informs developability and drug product strategies.•Evolving drug discovery solubility assays incorporate developm...

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Veröffentlicht in:	Drug discovery today Jg. 27; H. 5; S. 1315 - 1325
Hauptverfasser:	Barrett, Jaclyn A., Yang, Wenzhan, Skolnik, Suzanne M., Belliveau, Lisa M., Patros, Kellyn M.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Elsevier Ltd 01.05.2022
Schlagworte:	Data interpretation Drug Design Drug Development Drug Discovery Early drug development Experimental design Pharmaceutical Preparations Solubility Solubility approach Drug discovery Experimental design Solubility approach Early drug development Data interpretation
ISSN:	1359-6446, 1878-5832, 1878-5832
Online-Zugang:	Volltext
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