Decreased Serum Levels of Sphingomyelins and Ceramides in Sickle Cell Disease Patients

Limited data are available on the serum levels of different sphingomyelin (CerPCho) and ceramide (CER) species in sickle‐cell disease (SCD). This study was aimed at identifying the levels of C16–C24 CerPCho and C16–C24 CER in serum obtained from SCD patients and controls. Circulating levels of neutr...

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Veröffentlicht in:	Lipids Jg. 53; H. 3; S. 313 - 322
Hauptverfasser:	Aslan, Mutay, Kıraç, Ebru, Kaya, Sabriye, Özcan, Filiz, Salim, Ozan, Küpesiz, Osman Alphan
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken, USA John Wiley & Sons, Inc 01.03.2018
Schlagworte:	Adolescent Anemia, Sickle Cell - blood blood serum Case-Control Studies Ceramide ceramides Ceramides - blood Ceramides - classification Child cholesterol Cholesterol, HDL - blood Cholesterol, LDL - blood Cholesterol, VLDL - blood Chromatography, High Pressure Liquid enzyme-linked immunosorbent assay Female hemoglobin homozygosity Humans Lysophospholipids - blood Male Neutral sphingomyelinase pathophysiology sickle cell anemia Sickle cell disease Sphingomyelin Sphingomyelin Phosphodiesterase - blood sphingomyelins Sphingomyelins - blood Sphingomyelins - classification Sphingosine - analogs & derivatives Sphingosine - blood Tandem Mass Spectrometry Triglycerides - blood ultrafast liquid chromatography Ceramide Sphingomyelin Sickle cell disease Neutral sphingomyelinase
ISSN:	0024-4201, 1558-9307, 1558-9307
Online-Zugang:	Volltext
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