Transforming growth factor-β in tissue fibrosis
TGF-β is extensively implicated in the pathogenesis of fibrosis. In fibrotic lesions, spatially restricted generation of bioactive TGF-β from latent stores requires the cooperation of proteases, integrins, and specialized extracellular matrix molecules. Although fibroblasts are major targets of TGF-...
Saved in:
| Published in: | The Journal of experimental medicine Vol. 217; no. 3; p. e20190103 |
|---|---|
| Main Author: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
02.03.2020
|
| ISSN: | 1540-9538, 1540-9538 |
| Online Access: | Get more information |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!