Doxycycline‐loaded carboxymethyl cellulose/sodium alginate/gelatin hydrogel: An approach for enhancing pressure ulcer healing in a rat model

Pressure ulcers, or bedsores, are created by areas of the skin under prolonged pressure and can lead to skin and underlying tissue damage. The present study evaluated the effects of carboxymethyl cellulose/sodium alginate/gelatin (CMC/Alg/Gel) hydrogel containing doxycycline (DOX) on improving the h...

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Bibliographic Details
Published in:	Journal of biomedical materials research. Part A Vol. 112; no. 12; pp. 2289 - 2300
Main Authors:	Aldaghi, Niloofar, Kamalabadi‐Farahani, Mohammad, Alizadeh, Morteza, Salehi, Majid
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01.12.2024 Wiley Subscription Services, Inc
Subjects:	Alginates - chemistry Alginates - pharmacology Alginic acid Animals Antibiotics bedsore Biocompatibility Carboxymethyl cellulose Carboxymethylcellulose Carboxymethylcellulose Sodium - chemistry Cell viability Cellulose Damage assessment Disease Models, Animal Doxycycline Doxycycline - pharmacology Gelatin Gelatin - chemistry Gelatinase A Gelatinase B Gene expression Growth factors Healing hydrogel Hydrogels Hydrogels - chemistry Hydrogels - pharmacology Male mRNA Pressure Pressure effects Pressure Ulcer - drug therapy Pressure Ulcer - pathology Pressure ulcers Rats Rats, Sprague-Dawley Skin Sodium Sodium alginate Ulcers Vascular endothelial growth factor Vascular Endothelial Growth Factor A - metabolism Weight loss Wound healing Wound Healing - drug effects pressure ulcers wound healing bedsore doxycycline hydrogel
ISSN:	1549-3296, 1552-4965, 1552-4965
Online Access:	Get full text
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