Visual functions in non-overlapping visual field defects: dichoptic experiments in healthy subjects with simulated scotomas

In clinical care, glaucoma patients are often assumed to have normal vision as long as each point of visual space is seen normally by at least one eye. Recent studies have challenged this assumption. In glaucoma, visual perception of spatially fragmented binocular input may be altered by long-term n...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Vision research (Oxford) Jg. 235; S. 108666
Hauptverfasser: Gazanchian, Mehrdad, Cornelissen, Frans W., Jansonius, Nomdo M.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Elsevier Ltd 01.10.2025
Schlagworte:
Adult
Contrast Sensitivity - physiology
Cross-Sectional Studies
Female
Form Perception - physiology
Humans
Male
Middle Aged
Motion Perception - physiology
Pattern Recognition, Visual - physiology
Photic Stimulation - methods
Psychophysics
Scotoma - physiopathology
Vision, Binocular - physiology
Vision, Monocular - physiology
Visual Fields - physiology
Visual Perception - physiology
Young Adult
ISSN:0042-6989, 1878-5646, 1878-5646
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In clinical care, glaucoma patients are often assumed to have normal vision as long as each point of visual space is seen normally by at least one eye. Recent studies have challenged this assumption. In glaucoma, visual perception of spatially fragmented binocular input may be altered by long-term neural adaptation and by acute sensory effects. These two components cannot be disentangled easily in glaucoma patients, but the latter component can be isolated with simulated visual field defects in healthy subjects. Therefore, the aim of this study was to find out if simulated non-overlapping visual field defects (NOVFDs) can hamper certain aspects of visual perception in healthy subjects. We included 10 healthy subjects in this cross-sectional, observational study. Subjects underwent psychophysical experiments targeting contrast sensitivity, motion perception (line motion and coherent dot motion), and shape recognition. Experiments were done in three different viewing conditions using a stereoscope: (1) binocularly, (2) with simulated NOVFDs, and (3) monocularly. The NOVFDs viewing condition resulted in a decreased performance across all tested aspects of visual perception, when compared to the binocular viewing condition. The NOVFDs viewing condition resulted in a poorer performance in shape recognition compared to the monocular viewing condition. No other differences were observed between these two viewing conditions. Our results show that simulated NOVFDs impair certain visual functions. This contributes to the basic understanding of visual perception in healthy subjects and acts as a first step in the understanding of the relationship between disease stage and the visual problems that glaucoma patients may experience.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0042-6989
1878-5646
1878-5646
DOI:10.1016/j.visres.2025.108666