Hyaluronic Acid Improves the Tolerability of Hypertonic Saline in the Chronic Treatment of Cystic Fibrosis Patients: A Multicenter, Randomized, Controlled Clinical Trial

Abstract Trial Design and Methods: Between December 2009 and July 2011, four cystic fibrosis (CF) centers in Italy participated in a randomized, double-blind, controlled clinical trial to test whether 7% hypertonic saline (HS) administered together with 0.1% hyaluronic acid (HA) was better tolerated...

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Bibliographic Details
Published in:	Journal of aerosol medicine Vol. 27; no. 2; pp. 133 - 137
Main Authors:	Ros, Mirco, Casciaro, Rosaria, Lucca, Francesca, Troiani, Patrizia, Salonini, Elena, Favilli, Federica, Quattrucci, Serena, Sher, Daniel, Assael, Baroukh Maurice
Format:	Journal Article
Language:	English
Published:	Los Angeles, CA SAGE Publications 01.04.2014 Mary Ann Liebert, Inc
Subjects:	Administration, Inhalation Adolescent Child Cough - chemically induced Cystic Fibrosis - diagnosis Cystic Fibrosis - drug therapy Cystic Fibrosis - physiopathology Double-Blind Method Drug Administration Schedule Female Forced Expiratory Volume Humans Hyaluronic Acid - administration & dosage Hyaluronic Acid - adverse effects Italy Lung - drug effects Lung - physiopathology Male Patient Compliance Saline Solution, Hypertonic - administration & dosage Saline Solution, Hypertonic - adverse effects Taste Time Factors Treatment Outcome Young Adult Italy clinical trial inhaled therapy cystic fibrosis hypertonic saline hyaluronan
ISSN:	1941-2711, 1941-2703, 1941-2703
Online Access:	Get full text
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