Nutritional and Gastrointestinal Management of the Patient With Duchenne Muscular Dystrophy

Advances in treatment and multidisciplinary management have resulted in improved survival of individuals with Duchenne muscular dystrophy (DMD). Updated DMD treatment recommendations as found in the 2018 DMD Care Considerations are aimed to assist multidisciplinary care teams in providing standardiz...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics (Evanston) Vol. 142; no. Suppl 2; p. S53
Main Authors: Brumbaugh, David, Watne, Laura, Gottrand, Frederic, Gulyas, Ann, Kaul, Ajay, Larson, Jacqueline, Tomezsko, Jean
Format: Journal Article
Language:English
Published: United States 01.10.2018
ISSN:1098-4275, 1098-4275
Online Access:Get more information
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract Advances in treatment and multidisciplinary management have resulted in improved survival of individuals with Duchenne muscular dystrophy (DMD). Updated DMD treatment recommendations as found in the 2018 DMD Care Considerations are aimed to assist multidisciplinary care teams in providing standardized care to their patients, including attention to nutritional and gastrointestinal health. Challenges remain for care teams in accurately estimating height and nutritional status for individuals with DMD. It can be difficult for patients to maintain a healthy weight. Risk factors for obesity include glucocorticoid therapy and loss of ambulation. In contrast, in the later stages of the disease, swallowing dysfunction can lead to poor nutrition and consideration for gastrostomy tube placement. Constipation is highly prevalent, underrecognized, and undertreated in DMD. With this article, we address the assessment and management of gastrointestinal and nutritional issues, as well as clinical controversies.
AbstractList Advances in treatment and multidisciplinary management have resulted in improved survival of individuals with Duchenne muscular dystrophy (DMD). Updated DMD treatment recommendations as found in the 2018 DMD Care Considerations are aimed to assist multidisciplinary care teams in providing standardized care to their patients, including attention to nutritional and gastrointestinal health. Challenges remain for care teams in accurately estimating height and nutritional status for individuals with DMD. It can be difficult for patients to maintain a healthy weight. Risk factors for obesity include glucocorticoid therapy and loss of ambulation. In contrast, in the later stages of the disease, swallowing dysfunction can lead to poor nutrition and consideration for gastrostomy tube placement. Constipation is highly prevalent, underrecognized, and undertreated in DMD. With this article, we address the assessment and management of gastrointestinal and nutritional issues, as well as clinical controversies.Advances in treatment and multidisciplinary management have resulted in improved survival of individuals with Duchenne muscular dystrophy (DMD). Updated DMD treatment recommendations as found in the 2018 DMD Care Considerations are aimed to assist multidisciplinary care teams in providing standardized care to their patients, including attention to nutritional and gastrointestinal health. Challenges remain for care teams in accurately estimating height and nutritional status for individuals with DMD. It can be difficult for patients to maintain a healthy weight. Risk factors for obesity include glucocorticoid therapy and loss of ambulation. In contrast, in the later stages of the disease, swallowing dysfunction can lead to poor nutrition and consideration for gastrostomy tube placement. Constipation is highly prevalent, underrecognized, and undertreated in DMD. With this article, we address the assessment and management of gastrointestinal and nutritional issues, as well as clinical controversies.
Advances in treatment and multidisciplinary management have resulted in improved survival of individuals with Duchenne muscular dystrophy (DMD). Updated DMD treatment recommendations as found in the 2018 DMD Care Considerations are aimed to assist multidisciplinary care teams in providing standardized care to their patients, including attention to nutritional and gastrointestinal health. Challenges remain for care teams in accurately estimating height and nutritional status for individuals with DMD. It can be difficult for patients to maintain a healthy weight. Risk factors for obesity include glucocorticoid therapy and loss of ambulation. In contrast, in the later stages of the disease, swallowing dysfunction can lead to poor nutrition and consideration for gastrostomy tube placement. Constipation is highly prevalent, underrecognized, and undertreated in DMD. With this article, we address the assessment and management of gastrointestinal and nutritional issues, as well as clinical controversies.
Author Gulyas, Ann
Tomezsko, Jean
Gottrand, Frederic
Kaul, Ajay
Brumbaugh, David
Watne, Laura
Larson, Jacqueline
Author_xml – sequence: 1
  givenname: David
  surname: Brumbaugh
  fullname: Brumbaugh, David
  email: david.brumbaugh@childrenscolorado.org
  organization: Children's Hospital Colorado, Aurora, Colorado; david.brumbaugh@childrenscolorado.org
– sequence: 2
  givenname: Laura
  surname: Watne
  fullname: Watne, Laura
  organization: Children's Hospital Colorado, Aurora, Colorado
– sequence: 3
  givenname: Frederic
  surname: Gottrand
  fullname: Gottrand, Frederic
  organization: Jean de Flandre Hospital, Université de Lille, Centre Hospitalier Régional Universitaire de Lille, Lille, France
– sequence: 4
  givenname: Ann
  surname: Gulyas
  fullname: Gulyas, Ann
  organization: Western Maryland Hospital Center, Hagerstown, Maryland
– sequence: 5
  givenname: Ajay
  surname: Kaul
  fullname: Kaul, Ajay
  organization: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
– sequence: 6
  givenname: Jacqueline
  surname: Larson
  fullname: Larson, Jacqueline
  organization: Jacqueline Larson and Associates, Newport Beach, California; and
– sequence: 7
  givenname: Jean
  surname: Tomezsko
  fullname: Tomezsko, Jean
  organization: Medical Nutrition Consulting of Media LLC, Philadelphia, Pennsylvania
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30275249$$D View this record in MEDLINE/PubMed
BookMark eNpNUDtPwzAYtFARfcDMhjyypPgRx8mIWihILTCAGBgiJ_5MjBInxM6Qf08risR0D51Op5ujiWsdIHRJyZKKmN10oP2SEZpGhHO-OUEzSrI0ipkUk398iubefxFCYiHZGZpysjdZnM3Qx9MQehts61SNldN4o3zoW-sC-GAP5k459QkNuIBbg0MF-EUFe5DvNlR4PZQVOAd4N_hyqFWP1-OhoavGc3RqVO3h4ogL9HZ_97p6iLbPm8fV7TYquchClJQ8FporZmKdGlpInRaEAlcmlRIUT4tEmdhwJiQQkxmgSUlSpqnIpBK6YAt0_dvb9e33sN-dN9aXUNfKQTv4nFEqpEhkJvbRq2N0KBrQedfbRvVj_ncI-wGqU2Y4
CitedBy_id crossref_primary_10_1089_chi_2024_0297
crossref_primary_10_1093_nutrit_nuz109
crossref_primary_10_1016_j_ejpn_2025_03_008
crossref_primary_10_7759_cureus_67901
crossref_primary_10_3390_children10060959
crossref_primary_10_1111_nmo_14804
crossref_primary_10_15252_emmm_202216225
crossref_primary_10_1155_carm_7873892
crossref_primary_10_1016_j_nmd_2023_10_004
crossref_primary_10_1016_j_nurpra_2024_105230
crossref_primary_10_1186_s12944_025_02628_0
crossref_primary_10_3233_JND_200609
crossref_primary_10_1007_s00455_019_09997_6
crossref_primary_10_1007_s00115_019_0754_y
crossref_primary_10_1016_j_nmd_2024_03_009
crossref_primary_10_1017_S1047951122001342
crossref_primary_10_3390_medicina56090426
crossref_primary_10_1097_WCO_0000000000000739
crossref_primary_10_1080_09638288_2021_1936221
crossref_primary_10_1016_j_jocn_2024_110857
crossref_primary_10_1055_s_0044_1787994
crossref_primary_10_3390_nu16132143
crossref_primary_10_5409_wjcp_v12_i4_197
crossref_primary_10_1002_mus_28028
crossref_primary_10_1002_mus_27970
crossref_primary_10_3390_metabo12020193
ContentType Journal Article
Copyright Copyright © 2018 by the American Academy of Pediatrics.
Copyright_xml – notice: Copyright © 2018 by the American Academy of Pediatrics.
DBID NPM
7X8
DOI 10.1542/peds.2018-0333G
DatabaseName PubMed
MEDLINE - Academic
DatabaseTitle PubMed
MEDLINE - Academic
DatabaseTitleList MEDLINE - Academic
PubMed
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: 7X8
  name: MEDLINE - Academic
  url: https://search.proquest.com/medline
  sourceTypes: Aggregation Database
DeliveryMethod no_fulltext_linktorsrc
Discipline Medicine
EISSN 1098-4275
ExternalDocumentID 30275249
Genre Journal Article
GroupedDBID ---
-ET
..I
.55
.GJ
0R~
123
18M
1CY
1HT
26-
29O
2KS
2QL
2WC
36B
39C
4.4
41~
53G
5RE
5VS
6PF
7K8
85S
8F7
8GL
96U
AAAMJ
AAHTB
AAIKC
AAJMC
AAKAS
AAMNW
AAQOH
AAWTL
AAWTO
AAYOK
ABCZD
ABIVO
ABJNI
ABOCM
ABPEJ
ABPPZ
ACBMB
ACGFO
ACGOD
ACNCT
ACPRK
ADCOW
ADZCM
AENEX
AFAZI
AFFNX
AFHKK
AFOSN
AFRAH
AGFXO
AHMBA
AJUXI
ALMA_UNASSIGNED_HOLDINGS
BKOMP
CS3
DIK
DU5
E3Z
EBS
EJD
ESX
EX3
F5P
F8P
FEDTE
GICCO
GOZPB
GX1
H13
HF~
HVGLF
IAG
IAO
ICJ
IEA
IER
IGG
IHR
IHW
IMI
INH
INR
IOF
IPO
IPY
ISE
ITC
IVC
KO8
KQ8
L7B
LXL
LXN
LXY
N4W
N9A
NEJ
NPM
OHT
OK1
OMK
OVD
P0W
P2P
PDE
PQQKQ
Q.-
RHF
RHI
SJN
TAE
TEORI
TR2
TWZ
UBE
UHB
UMD
VXZ
W8F
WH7
WHG
WOQ
WOW
WQ9
X7M
XJT
XOL
XZL
YCJ
YHG
YHZ
YOC
YQI
YQJ
YZZ
Z5M
ZGI
ZRR
ZXP
~KM
~X8
7X8
ABUFD
ID FETCH-LOGICAL-c359t-6c345d3a2f4d8f1b7d8b01e3af877ea38b6af4f3257e0f9fe16c082d1597a5db2
IEDL.DBID 7X8
ISICitedReferencesCount 28
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000511642900006&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 1098-4275
IngestDate Sun Nov 09 13:35:10 EST 2025
Wed Feb 19 02:34:14 EST 2025
IsPeerReviewed true
IsScholarly true
Issue Suppl 2
Language English
License Copyright © 2018 by the American Academy of Pediatrics.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c359t-6c345d3a2f4d8f1b7d8b01e3af877ea38b6af4f3257e0f9fe16c082d1597a5db2
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
PMID 30275249
PQID 2115756795
PQPubID 23479
ParticipantIDs proquest_miscellaneous_2115756795
pubmed_primary_30275249
PublicationCentury 2000
PublicationDate 2018-10-00
20181001
PublicationDateYYYYMMDD 2018-10-01
PublicationDate_xml – month: 10
  year: 2018
  text: 2018-10-00
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle Pediatrics (Evanston)
PublicationTitleAlternate Pediatrics
PublicationYear 2018
SSID ssj0004572
Score 2.4151049
Snippet Advances in treatment and multidisciplinary management have resulted in improved survival of individuals with Duchenne muscular dystrophy (DMD). Updated DMD...
SourceID proquest
pubmed
SourceType Aggregation Database
Index Database
StartPage S53
Title Nutritional and Gastrointestinal Management of the Patient With Duchenne Muscular Dystrophy
URI https://www.ncbi.nlm.nih.gov/pubmed/30275249
https://www.proquest.com/docview/2115756795
Volume 142
WOSCitedRecordID wos000511642900006&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText
inHoldings 1
isFullTextHit
isPrint
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3NS8MwFA_qRLz4_TG_iOA1bG2aJjmJqJuXlR0UBx5K0iS4SzvXTvC_96XtmBdB8NJDadPyvvrrey-_h9ANYNCQUu1ILCPus1WMaOM4CWimMxPKmPebYRM8ScRkIsdtwq1s2yqXMbEO1KbIfI68F3pWGBZzyW5nH8RPjfLV1XaExjrqUIAy3qr55CdbOG-qnVKQKOSspfZhUdibWePJugO_v4zS4e_4sv7ODHb_-4Z7aKdFmPiuMYl9tGbzA7Q1amvoh-gtWRLww1UqN3ioympeeN4IcHd_ctUSgwuHASHiccO-il-n1Tt-WICiITzj0aLpYsUPX34FUNgRehk8Pt8_kXbEAskokxWJMxoxQ1XoIiNcoLkRuh9Yqpzg3CoqdKxc5Cg4tu076WwQZwAaDIAgrpjR4THayIvcniKstYcCzkrhaASragvRgwtmDDxEGNdF10uxpWDCvi6hclssynQluC46aWSfzhqujbQuq8Iv4tkf7j5H27VG61a7C9Rx4MD2Em1mn9W0nF_VtgHHZDz6BqSUxOc
linkProvider ProQuest
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Nutritional+and+Gastrointestinal+Management+of+the+Patient+With+Duchenne+Muscular+Dystrophy&rft.jtitle=Pediatrics+%28Evanston%29&rft.au=Brumbaugh%2C+David&rft.au=Watne%2C+Laura&rft.au=Gottrand%2C+Frederic&rft.au=Gulyas%2C+Ann&rft.date=2018-10-01&rft.issn=1098-4275&rft.eissn=1098-4275&rft.volume=142&rft.issue=Suppl+2&rft.spage=S53&rft_id=info:doi/10.1542%2Fpeds.2018-0333G&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1098-4275&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1098-4275&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1098-4275&client=summon