Model-assisted design of experiments in the presence of network-correlated outcomes

SUMMARY In this paper we consider how to assign treatment in a randomized experiment in which the correlation among the outcomes is informed by a network available pre-intervention. Working within the potential outcome causal framework, we develop a class of models that posit such a correlation stru...

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Vydáno v:Biometrika Ročník 105; číslo 4; s. 849 - 858
Hlavní autoři: Basse, Guillaume W, Airoldi, Edoardo M
Médium: Journal Article
Jazyk:angličtina
Vydáno: Oxford University Press 01.12.2018
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ISSN:0006-3444, 1464-3510
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Shrnutí:SUMMARY In this paper we consider how to assign treatment in a randomized experiment in which the correlation among the outcomes is informed by a network available pre-intervention. Working within the potential outcome causal framework, we develop a class of models that posit such a correlation structure among the outcomes. We use these models to develop restricted randomization strategies for allocating treatment optimally, by minimizing the mean squared error of the estimated average treatment effect. Analytical decompositions of the mean squared error, due both to the model and to the randomization distribution, provide insights into aspects of the optimal designs. In particular, the analysis suggests new notions of balance based on specific network quantities, in addition to classical covariate balance. The resulting balanced optimal restricted randomization strategies are still design-unbiased when the model used to derive them does not hold. We illustrate how the proposed treatment allocation strategies improve on allocations that ignore the network structure.
ISSN:0006-3444
1464-3510
DOI:10.1093/biomet/asy036