NK-like CD8+ cells in immunologically naïve neonatal calves that respond to dendritic cells infected with Mycobacterium bovis BCG

Pre‐exposure to environmental mycobacteria and induction of an inappropriately biased immune response may be major factors affecting the efficacy of BCG; vaccination of neonates that have not been exposed to environmental mycobacteria may induce more effective immunity. Responses of neonatal calves...

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Bibliographic Details
Published in:	Journal of leukocyte biology Vol. 71; no. 2; pp. 184 - 194
Main Authors:	Hope, Jayne C., Sopp, Paul, Howard, Chris J.
Format:	Journal Article
Language:	English
Published:	United States Society for Leukocyte Biology 01.02.2002
Subjects:	Animals Animals, Newborn Antigen Presentation antigen‐presenting cells BCG Vaccine Cattle CD8 Antigens Cytotoxicity, Immunologic Dendritic Cells - immunology IFN‐γ Immunity Killer Cells, Natural - immunology mycobacteria Mycobacterium bovis - immunology NKT cells Th1 Cells - immunology Tuberculosis, Bovine - immunology Tuberculosis, Bovine - prevention & control
ISSN:	0741-5400, 1938-3673
Online Access:	Get full text
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