On regression adjustments to experimental data

Regression adjustments are often made to experimental data. Since randomization does not justify the models, almost anything can happen. Here, we evaluate results using Neyman's non-parametric model, where each subject has two potential responses, one if treated and the other if untreated. Only...

Full description

Saved in:
Bibliographic Details
Published in:Advances in applied mathematics Vol. 40; no. 2; pp. 180 - 193
Main Author: Freedman, David A.
Format: Journal Article
Language:English
Published: San Diego, CA Elsevier Inc 01.02.2008
Elsevier
Subjects:
ISSN:0196-8858, 1090-2074
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract Regression adjustments are often made to experimental data. Since randomization does not justify the models, almost anything can happen. Here, we evaluate results using Neyman's non-parametric model, where each subject has two potential responses, one if treated and the other if untreated. Only one of the two responses is observed. Regression estimates are generally biased, but the bias is small with large samples. Adjustment may improve precision, or make precision worse; standard errors computed according to usual procedures may overstate the precision, or understate, by quite large factors. Asymptotic expansions make these ideas more precise.
AbstractList Regression adjustments are often made to experimental data. Since randomization does not justify the models, almost anything can happen. Here, we evaluate results using Neyman's non-parametric model, where each subject has two potential responses, one if treated and the other if untreated. Only one of the two responses is observed. Regression estimates are generally biased, but the bias is small with large samples. Adjustment may improve precision, or make precision worse; standard errors computed according to usual procedures may overstate the precision, or understate, by quite large factors. Asymptotic expansions make these ideas more precise.
Author Freedman, David A.
Author_xml – sequence: 1
  givenname: David A.
  surname: Freedman
  fullname: Freedman, David A.
  email: freedman@stat.berkeley.edu
  organization: Statistics Department, University of California, Berkeley, CA 94720-3860, USA
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20081216$$DView record in Pascal Francis
BookMark eNp9kD1PwzAQhi1UJNrCD2DLAluCv-I4YkIVX1KlLjBbV-eCHKVJsV0E_x5XLQtDlzud9D6nu2dGJsM4ICHXjBaMMnXXFQCbglOqCsYLSsUZmTJa05zTSk7IlLJa5VqX-oLMQugopTVXYkqK1ZB5_PAYghuHDJpuF-IGhxiyOGb4vUXv9iP0WQMRLsl5C33Aq2Ofk_enx7fFS75cPb8uHpa5FaWOuRRcUmVxrWWbqrRKcW0ZNGuBstWVVLKqLZRr1jDRIqimEVKJFrRCwSQVc3J72Lv14-cOQzQbFyz2PQw47oIRoqwk5zIFb45BCBb61sNgXTDbdDX4H5OEaMaZSrnqkLN-DMFja6yLENPP0YPrDaNm79F0JnncY8owbpLHRLJ_5N_yU8z9gcHk6MuhN8E6HCw2zqONphndCfoXZGCMJA
CODEN AAPMEF
CitedBy_id crossref_primary_10_1177_0193841X13513025
crossref_primary_10_1080_07418825_2019_1707857
crossref_primary_10_1111_ajae_12099
crossref_primary_10_3390_ijerph13040414
crossref_primary_10_1007_s13524_011_0029_0
crossref_primary_10_1214_16_STS582
crossref_primary_10_1177_1065912918781049
crossref_primary_10_1016_j_jeconom_2021_04_007
crossref_primary_10_1007_s11166_020_09322_9
crossref_primary_10_1007_s11292_012_9146_z
crossref_primary_10_1016_j_spl_2020_108945
crossref_primary_10_1016_j_jpubeco_2019_104123
crossref_primary_10_1093_ectj_utaa022
crossref_primary_10_1002_hec_1748
crossref_primary_10_1073_pnas_2213824120
crossref_primary_10_1002_bimj_201200104
crossref_primary_10_1111_biom_12148
crossref_primary_10_1017_S0020818315000107
crossref_primary_10_1177_00031224221075783
crossref_primary_10_1016_j_spl_2008_03_008
crossref_primary_10_1515_jbnst_2018_0016
crossref_primary_10_1111_jssr_12692
crossref_primary_10_1080_19466315_2018_1458648
crossref_primary_10_1214_17_AOS1605
crossref_primary_10_1111_lsq_12009
crossref_primary_10_1214_16_STS571
crossref_primary_10_3102_1076998611432176
crossref_primary_10_1016_j_jeconom_2021_12_010
crossref_primary_10_1080_07474938_2025_2538843
crossref_primary_10_1002_hec_4509
crossref_primary_10_1186_s12874_024_02375_3
crossref_primary_10_1177_13684302211012783
crossref_primary_10_1016_j_jebo_2013_06_012
crossref_primary_10_1214_23_AOS2308
crossref_primary_10_1080_01621459_2021_1906685
crossref_primary_10_1177_0193841X20906232
crossref_primary_10_1080_07474938_2020_1824732
crossref_primary_10_1111_rssb_12290
crossref_primary_10_1002_sim_4301
crossref_primary_10_1177_14624745211059318
crossref_primary_10_1017_pan_2018_42
crossref_primary_10_1093_biomet_asaa103
crossref_primary_10_1111_j_1540_5907_2011_00517_x
crossref_primary_10_1080_24709360_2021_1898269
crossref_primary_10_1111_j_1541_0420_2008_01177_x
crossref_primary_10_1186_s12884_020_03220_3
crossref_primary_10_1080_00401706_2022_2142670
crossref_primary_10_1093_biomet_asab051
crossref_primary_10_3354_cr01734
crossref_primary_10_1080_21565503_2013_872998
crossref_primary_10_1177_0193841X14548918
crossref_primary_10_3982_QE1744
crossref_primary_10_1080_01621459_2021_1941053
crossref_primary_10_1007_s11292_019_09363_4
crossref_primary_10_1080_14631377_2021_1886788
crossref_primary_10_1177_23780231231182908
crossref_primary_10_1016_j_fluid_2019_112429
crossref_primary_10_1093_biomet_asy034
crossref_primary_10_1016_j_socnet_2019_08_001
crossref_primary_10_1002_ajae_12038
crossref_primary_10_1111_isqu_12045
crossref_primary_10_1002_sim_9843
crossref_primary_10_1016_j_biocon_2020_108595
crossref_primary_10_1080_07350015_2024_2394576
crossref_primary_10_1086_676330
crossref_primary_10_1007_s11292_010_9095_3
crossref_primary_10_1073_pnas_1614732113
crossref_primary_10_1111_ajps_12846
crossref_primary_10_1111_rssb_12439
crossref_primary_10_1145_3365677
crossref_primary_10_1371_journal_pone_0132102
crossref_primary_10_1007_s13209_023_00279_x
crossref_primary_10_1080_07418825_2018_1531142
crossref_primary_10_3102_10769986211070625
crossref_primary_10_1016_j_jspi_2020_07_002
crossref_primary_10_3102_0162373714558292
crossref_primary_10_1214_09_STS274REJ
crossref_primary_10_1214_22_STS851
crossref_primary_10_1016_j_jeconom_2022_08_010
crossref_primary_10_3102_1076998609353112
crossref_primary_10_1177_0193841X12439195
crossref_primary_10_1002_sta4_461
crossref_primary_10_1515_spp_2013_0002
crossref_primary_10_1016_j_jeconom_2024_105724
crossref_primary_10_1080_01621459_2024_2366043
crossref_primary_10_3102_10769986251342292
crossref_primary_10_1002_pam_70007
crossref_primary_10_1007_s11292_019_09370_5
crossref_primary_10_1016_j_cct_2019_04_016
crossref_primary_10_3982_ECTA19303
crossref_primary_10_1080_19466315_2023_2267774
crossref_primary_10_1146_annurev_polisci_11_060606_135444
crossref_primary_10_1093_biomet_asz026
crossref_primary_10_1111_j_1540_5907_2011_00576_x
crossref_primary_10_1186_s13063_022_06967_6
crossref_primary_10_1016_j_jclinepi_2025_111674
crossref_primary_10_1111_sjoe_12581
crossref_primary_10_3982_ECTA12675
crossref_primary_10_1093_ijpor_edy019
crossref_primary_10_2139_ssrn_1444912
crossref_primary_10_1093_biomet_ast045
crossref_primary_10_1093_ectj_utz017
crossref_primary_10_1111_ecin_12940
crossref_primary_10_1016_j_econedurev_2021_102215
crossref_primary_10_1080_00031305_2020_1717619
crossref_primary_10_1002_sim_9585
crossref_primary_10_1073_pnas_2415066121
crossref_primary_10_1016_j_jeconom_2025_106049
crossref_primary_10_1111_rssb_12240
crossref_primary_10_1016_j_worlddev_2024_106591
crossref_primary_10_1080_07350015_2023_2224851
crossref_primary_10_1111_1745_9133_12644
crossref_primary_10_1016_j_ecotra_2020_100192
crossref_primary_10_1080_00031305_2023_2216247
crossref_primary_10_1177_23294965211053832
crossref_primary_10_1016_j_jeconom_2025_105991
crossref_primary_10_3934_mbe_2025048
crossref_primary_10_1016_j_jdeveco_2011_11_001
crossref_primary_10_1016_j_csda_2022_107554
crossref_primary_10_1080_07350015_2024_2403381
crossref_primary_10_1016_j_jspi_2009_07_008
crossref_primary_10_1016_j_spl_2011_10_024
crossref_primary_10_1080_01621459_2022_2123814
crossref_primary_10_1007_s11292_020_09447_6
crossref_primary_10_1016_j_jspi_2021_11_005
crossref_primary_10_1111_1745_9133_12506
crossref_primary_10_3102_1076998619855350
crossref_primary_10_1111_1467_8489_12325
crossref_primary_10_1002_pst_2155
crossref_primary_10_2139_ssrn_1508533
crossref_primary_10_1177_0193841X09337356
crossref_primary_10_1016_j_jeconom_2024_105740
crossref_primary_10_1177_0193841X09337991
crossref_primary_10_1186_s12874_025_02456_x
crossref_primary_10_1214_21_AOS2144
crossref_primary_10_1016_j_socscimed_2017_12_005
crossref_primary_10_1080_01621459_2022_2102985
crossref_primary_10_3102_1076998620941469
crossref_primary_10_1007_s11292_021_09488_5
crossref_primary_10_1002_pst_1988
crossref_primary_10_1214_08_STS262
crossref_primary_10_1177_03795721231194124
crossref_primary_10_1007_s11109_016_9379_z
crossref_primary_10_1515_jci_2022_0011
crossref_primary_10_1017_psrm_2015_62
crossref_primary_10_1515_ijb_2021_0072
crossref_primary_10_2139_ssrn_4767794
crossref_primary_10_3102_1076998618786968
crossref_primary_10_1093_ijpor_edy035
crossref_primary_10_1093_ectj_utae003
crossref_primary_10_1007_s11109_020_09620_7
crossref_primary_10_1093_ije_dyr152
crossref_primary_10_1111_j_1467_9868_2012_01048_x
crossref_primary_10_1214_24_AOS2454
crossref_primary_10_1257_pol_20230100
crossref_primary_10_1177_0193841X14549765
crossref_primary_10_1080_00031305_2022_2054859
crossref_primary_10_1111_j_1751_5823_2012_00185_x
crossref_primary_10_1177_0193841X18808003
crossref_primary_10_1016_j_jclinepi_2020_10_012
crossref_primary_10_1073_pnas_1510506113
crossref_primary_10_1111_rssb_12468
crossref_primary_10_3982_ECTA18640
crossref_primary_10_1017_S0008423915000268
crossref_primary_10_1093_jrsssb_qkac003
crossref_primary_10_3402_gha_v8_29724
crossref_primary_10_1093_jopart_muac054
crossref_primary_10_1002_sta4_70058
crossref_primary_10_1080_07418825_2020_1821086
crossref_primary_10_1080_00031305_2017_1322143
crossref_primary_10_1080_01621459_2025_2516197
crossref_primary_10_1080_21620555_2021_1967737
crossref_primary_10_1177_00938548241297690
crossref_primary_10_1080_00220388_2013_828835
crossref_primary_10_1016_j_jeconom_2024_105808
crossref_primary_10_1177_1098214015621787
crossref_primary_10_1186_s11556_024_00367_2
crossref_primary_10_1257_jel_48_2_399
crossref_primary_10_1002_pam_22617
crossref_primary_10_1016_j_socec_2019_101469
crossref_primary_10_1257_jel_48_2_424
crossref_primary_10_3982_ECTA20289
crossref_primary_10_1080_23311932_2025_2481421
crossref_primary_10_3102_1076998609332748
crossref_primary_10_1080_01621459_2017_1295865
crossref_primary_10_1016_j_socscimed_2018_05_012
crossref_primary_10_1214_12_AOS1008
crossref_primary_10_1111_rssb_12353
crossref_primary_10_1093_biomet_asad036
crossref_primary_10_1080_01621459_2025_2526700
Cites_doi 10.1001/jama.295.6.655
10.1093/pan/mpj001
10.1111/j.1468-0262.2004.00539.x
10.1093/aje/kwi224
10.2105/AJPH.94.3.400
10.1093/aje/kwi223
10.1002/(SICI)1097-0258(19980815/30)17:15/16<1863::AID-SIM989>3.0.CO;2-M
10.1161/01.CIR.99.6.779
10.1002/sim.4780122411
10.1080/01621459.1986.10478354
10.1111/j.0006-341X.2005.454_1.x
10.1002/sim.1583
10.1214/aos/1176344670
10.1001/jama.288.3.321
10.1214/aos/1176345638
10.1177/0193841X06293771
10.1023/A:1005285815569
10.1007/BF00536301
ContentType Journal Article
Copyright 2007
2008 INIST-CNRS
Copyright_xml – notice: 2007
– notice: 2008 INIST-CNRS
DBID 6I.
AAFTH
AAYXX
CITATION
IQODW
7SC
7TB
8FD
FR3
JQ2
KR7
L7M
L~C
L~D
DOI 10.1016/j.aam.2006.12.003
DatabaseName ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
CrossRef
Pascal-Francis
Computer and Information Systems Abstracts
Mechanical & Transportation Engineering Abstracts
Technology Research Database
Engineering Research Database
ProQuest Computer Science Collection
Civil Engineering Abstracts
Advanced Technologies Database with Aerospace
Computer and Information Systems Abstracts – Academic
Computer and Information Systems Abstracts Professional
DatabaseTitle CrossRef
Civil Engineering Abstracts
Technology Research Database
Computer and Information Systems Abstracts – Academic
Mechanical & Transportation Engineering Abstracts
ProQuest Computer Science Collection
Computer and Information Systems Abstracts
Engineering Research Database
Advanced Technologies Database with Aerospace
Computer and Information Systems Abstracts Professional
DatabaseTitleList
Civil Engineering Abstracts
DeliveryMethod fulltext_linktorsrc
Discipline Mathematics
EISSN 1090-2074
EndPage 193
ExternalDocumentID 20081216
10_1016_j_aam_2006_12_003
S019688580700005X
GroupedDBID --K
--M
-~X
.~1
0R~
1B1
1RT
1~.
1~5
23M
4.4
457
4G.
5GY
5VS
6I.
7-5
71M
8P~
9JN
AACTN
AAEDT
AAEDW
AAFTH
AAIAV
AAIKJ
AAKOC
AALRI
AAOAW
AAQFI
AAQXK
AASFE
AAXUO
ABAOU
ABFNM
ABJNI
ABMAC
ABVKL
ABXDB
ABYKQ
ACAZW
ACDAQ
ACGFS
ACRLP
ADBBV
ADEZE
ADFGL
ADMUD
AEBSH
AEKER
AENEX
AEXQZ
AFKWA
AFTJW
AGHFR
AGUBO
AGYEJ
AHHHB
AIEXJ
AIGVJ
AIKHN
AITUG
AJBFU
AJOXV
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ARUGR
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLXMC
CAG
COF
CS3
DM4
EBS
EFBJH
EFLBG
EJD
EO8
EO9
EP2
EP3
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
GBLVA
HVGLF
HZ~
IHE
IXB
J1W
KOM
LG5
M25
M41
MHUIS
MO0
N9A
NCXOZ
O-L
O9-
OAUVE
OK1
OZT
P-8
P-9
P2P
PC.
Q38
R2-
RIG
RNS
ROL
RPZ
SDF
SDG
SDP
SES
SEW
SPC
SPCBC
SSW
SSZ
T5K
TN5
UPT
VOH
WUQ
XPP
ZMT
~G-
9DU
AATTM
AAXKI
AAYWO
AAYXX
ABWVN
ACLOT
ACRPL
ACVFH
ADCNI
ADNMO
ADVLN
AEIPS
AEUPX
AFJKZ
AFPUW
AGQPQ
AIGII
AIIUN
AKBMS
AKRWK
AKYEP
ANKPU
APXCP
CITATION
EFKBS
~HD
AFXIZ
AGCQF
AGRNS
BNPGV
IQODW
SSH
7SC
7TB
8FD
FR3
JQ2
KR7
L7M
L~C
L~D
ID FETCH-LOGICAL-c358t-432406ceb84fceb4c6628c1adb3e4f8746479ca5b1d13fea6dd3463fa86e31403
ISICitedReferencesCount 231
ISICitedReferencesURI http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000253878000004&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN 0196-8858
IngestDate Wed Oct 01 14:00:57 EDT 2025
Mon Jul 21 09:15:52 EDT 2025
Sat Nov 29 07:20:28 EST 2025
Tue Nov 18 22:49:43 EST 2025
Fri Feb 23 02:34:44 EST 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 2
Keywords Randomization
62A01
Models
Balance
62J99
Multiple regression
Intention-to-treat
Asymptotic expansion
Error estimation
Applied mathematics
62J99. Models
Language English
License http://www.elsevier.com/open-access/userlicense/1.0
CC BY 4.0
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c358t-432406ceb84fceb4c6628c1adb3e4f8746479ca5b1d13fea6dd3463fa86e31403
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
OpenAccessLink https://dx.doi.org/10.1016/j.aam.2006.12.003
PQID 33574224
PQPubID 23500
PageCount 14
ParticipantIDs proquest_miscellaneous_33574224
pascalfrancis_primary_20081216
crossref_citationtrail_10_1016_j_aam_2006_12_003
crossref_primary_10_1016_j_aam_2006_12_003
elsevier_sciencedirect_doi_10_1016_j_aam_2006_12_003
PublicationCentury 2000
PublicationDate 2008-02-01
PublicationDateYYYYMMDD 2008-02-01
PublicationDate_xml – month: 02
  year: 2008
  text: 2008-02-01
  day: 01
PublicationDecade 2000
PublicationPlace San Diego, CA
PublicationPlace_xml – name: San Diego, CA
PublicationTitle Advances in applied mathematics
PublicationYear 2008
Publisher Elsevier Inc
Elsevier
Publisher_xml – name: Elsevier Inc
– name: Elsevier
References Howard, Van Horn, Hsia (bib015) 2006; 295
Petitti, Freedman (bib019) 2005; 162
Koch, Tangen, Jung, Amara (bib016) 1998; 17
Anderson, Taylor (bib001) 1979; 7
Friedman, Furberg, DeMets (bib011) 2006
Holland (bib014) 1986; 8
Greene (bib012) 2003
Schmoor, Ulm, Schumacher (bib024) 1993; 12
Freedman (bib010) 2006; 30
Prentice, Langer, Stefanick (bib020) 2005; 162
Robins (bib022) 1999; 121
Shadish, Cook, Campbell (bib025) 2002
Freedman (bib009) 2005
Höglund (bib013) 1978; 5
Rossouw, Anderson, Prentice (bib023) 2002; 288
Dabrowska, Speed (bib005) 1990; 5
Drygas (bib007) 1971; 17
Neyman (bib018) 1923; 10
Arceneaux, Gerber, Green (bib002) 2006; 14
Freedman (bib008) 1981; 9
Prentice, Pettinger, Anderson (bib021) 2005; 61
(bib003) 2004
Chattopadhyay, Duflo (bib004) 2004; 72
Lesaffre, Senn (bib017) 2003; 22
de Lorgeril, Salen, Martin (bib006) 1999; 99
Victora, Habicht, Bryce (bib026) 2004; 94
Freedman (10.1016/j.aam.2006.12.003_bib009) 2005
Prentice (10.1016/j.aam.2006.12.003_bib020) 2005; 162
Arceneaux (10.1016/j.aam.2006.12.003_bib002) 2006; 14
Chattopadhyay (10.1016/j.aam.2006.12.003_bib004) 2004; 72
(10.1016/j.aam.2006.12.003_bib003) 2004
Anderson (10.1016/j.aam.2006.12.003_bib001) 1979; 7
Neyman (10.1016/j.aam.2006.12.003_bib018) 1923; 10
Holland (10.1016/j.aam.2006.12.003_bib014) 1986; 8
Freedman (10.1016/j.aam.2006.12.003_bib008) 1981; 9
Höglund (10.1016/j.aam.2006.12.003_bib013) 1978; 5
Robins (10.1016/j.aam.2006.12.003_bib022) 1999; 121
de Lorgeril (10.1016/j.aam.2006.12.003_bib006) 1999; 99
Drygas (10.1016/j.aam.2006.12.003_bib007) 1971; 17
Dabrowska (10.1016/j.aam.2006.12.003_bib005) 1990; 5
Schmoor (10.1016/j.aam.2006.12.003_bib024) 1993; 12
Petitti (10.1016/j.aam.2006.12.003_bib019) 2005; 162
Greene (10.1016/j.aam.2006.12.003_bib012) 2003
Shadish (10.1016/j.aam.2006.12.003_bib025) 2002
Victora (10.1016/j.aam.2006.12.003_bib026) 2004; 94
Koch (10.1016/j.aam.2006.12.003_bib016) 1998; 17
Rossouw (10.1016/j.aam.2006.12.003_bib023) 2002; 288
Friedman (10.1016/j.aam.2006.12.003_bib011) 2006
Prentice (10.1016/j.aam.2006.12.003_bib021) 2005; 61
Howard (10.1016/j.aam.2006.12.003_bib015) 2006; 295
Lesaffre (10.1016/j.aam.2006.12.003_bib017) 2003; 22
Freedman (10.1016/j.aam.2006.12.003_bib010) 2006; 30
References_xml – volume: 162
  start-page: 404
  year: 2005
  end-page: 414
  ident: bib020
  article-title: Combined postmenopausal hormone therapy and cardiovascular disease: Toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial
  publication-title: Amer. J. Epidemiology
– volume: 121
  start-page: 151
  year: 1999
  end-page: 179
  ident: bib022
  article-title: Association, causation, and marginal structural models
  publication-title: Synthese
– volume: 94
  start-page: 400
  year: 2004
  end-page: 405
  ident: bib026
  article-title: Evidence-based public health: Moving beyond randomized trials
  publication-title: Amer. J. Public Health
– volume: 10
  start-page: 1
  year: 1923
  end-page: 51
  ident: bib018
  article-title: Sur les applications de la théorie des probabilités aux experiences agricoles: Essai des principes
  publication-title: Roczniki Nauk Rolniczych
– year: 2004
  ident: bib003
  publication-title: Rethinking Social Inquiry: Diverse Tools, Shared Standards
– volume: 72
  start-page: 1409
  year: 2004
  end-page: 1443
  ident: bib004
  article-title: Women as policy makers: Evidence from a randomized policy experiment in India
  publication-title: Econometrica
– volume: 162
  start-page: 1
  year: 2005
  end-page: 4
  ident: bib019
  article-title: Invited commentary: How far can epidemiologists get with statistical adjustment?
  publication-title: Amer. J. Epidemiology
– volume: 295
  start-page: 655
  year: 2006
  end-page: 666
  ident: bib015
  article-title: Low-fat dietary pattern and risk of cardiovascular disease: The Women's Health Initiative randomized controlled dietary modification trial
  publication-title: J. Amer. Medical Assoc.
– year: 2002
  ident: bib025
  article-title: Experimental and Quasi-Experimental Designs for Generalized Causal Inference
– volume: 7
  start-page: 484
  year: 1979
  end-page: 489
  ident: bib001
  article-title: Strong consistency of least squares estimates in dynamic models
  publication-title: Ann. Statist.
– year: 2005
  ident: bib009
  article-title: Statistical Models: Theory and Practice
– volume: 22
  start-page: 3583
  year: 2003
  end-page: 3596
  ident: bib017
  article-title: A note on non-parametric ANCOVA for covariate adjustment in randomized clinical trials
  publication-title: Stat. Med.
– volume: 12
  start-page: 2351
  year: 1993
  end-page: 2368
  ident: bib024
  article-title: Comparison of the Cox model and the regression tree procedure in analysing a randomized clinical trial
  publication-title: Stat. Med.
– volume: 9
  start-page: 1218
  year: 1981
  end-page: 1228
  ident: bib008
  article-title: Bootstrapping regression models
  publication-title: Ann. Statist.
– volume: 99
  start-page: 779
  year: 1999
  end-page: 785
  ident: bib006
  article-title: Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: Final report of the Lyon Diet Heart Study
  publication-title: Circulation
– volume: 5
  start-page: 69
  year: 1978
  end-page: 71
  ident: bib013
  article-title: Sampling from a finite population: A remainder term estimate
  publication-title: Scand. J. Statist.
– volume: 61
  start-page: 899
  year: 2005
  end-page: 941
  ident: bib021
  article-title: Statistical issues arising in the Women's Health Initiative
  publication-title: Biometrics
– volume: 8
  start-page: 945
  year: 1986
  end-page: 970
  ident: bib014
  article-title: Statistics and causal inference
  publication-title: J. Amer. Statist. Assoc.
– volume: 17
  start-page: 1863
  year: 1998
  end-page: 1892
  ident: bib016
  article-title: Issues for covariance analysis of dichotomous and ordered categorical data from randomized clinical trials and non-parametric strategies for addressing them
  publication-title: Stat. Med.
– volume: 17
  start-page: 309
  year: 1971
  end-page: 326
  ident: bib007
  article-title: Consistency of the least squares and Gauss–Markov estimators in regression models
  publication-title: Z. Wahrscheinlichkeitstheorie
– year: 2003
  ident: bib012
  article-title: Econometric Analysis
– volume: 288
  start-page: 321
  year: 2002
  end-page: 333
  ident: bib023
  article-title: Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
  publication-title: J. Amer. Med. Assoc.
– year: 2006
  ident: bib011
  article-title: Fundamentals of Clinical Trials
– volume: 30
  start-page: 691
  year: 2006
  end-page: 713
  ident: bib010
  article-title: Statistical models for causation: What inferential leverage do they provide?
  publication-title: Evaluation Review
– volume: 5
  start-page: 463
  year: 1990
  end-page: 480
  ident: bib005
  article-title: On the application of probability theory to agricultural experiments: Essay on principles
  publication-title: Statist. Sci.
– volume: 14
  start-page: 37
  year: 2006
  end-page: 62
  ident: bib002
  article-title: Comparing experimental and matching methods using a large-scale voter mobilization experiment
  publication-title: Polit. Anal.
– volume: 5
  start-page: 463
  year: 1990
  ident: 10.1016/j.aam.2006.12.003_bib005
  article-title: On the application of probability theory to agricultural experiments: Essay on principles
  publication-title: Statist. Sci.
– volume: 295
  start-page: 655
  year: 2006
  ident: 10.1016/j.aam.2006.12.003_bib015
  article-title: Low-fat dietary pattern and risk of cardiovascular disease: The Women's Health Initiative randomized controlled dietary modification trial
  publication-title: J. Amer. Medical Assoc.
  doi: 10.1001/jama.295.6.655
– volume: 14
  start-page: 37
  year: 2006
  ident: 10.1016/j.aam.2006.12.003_bib002
  article-title: Comparing experimental and matching methods using a large-scale voter mobilization experiment
  publication-title: Polit. Anal.
  doi: 10.1093/pan/mpj001
– volume: 72
  start-page: 1409
  year: 2004
  ident: 10.1016/j.aam.2006.12.003_bib004
  article-title: Women as policy makers: Evidence from a randomized policy experiment in India
  publication-title: Econometrica
  doi: 10.1111/j.1468-0262.2004.00539.x
– volume: 162
  start-page: 1
  year: 2005
  ident: 10.1016/j.aam.2006.12.003_bib019
  article-title: Invited commentary: How far can epidemiologists get with statistical adjustment?
  publication-title: Amer. J. Epidemiology
  doi: 10.1093/aje/kwi224
– volume: 94
  start-page: 400
  year: 2004
  ident: 10.1016/j.aam.2006.12.003_bib026
  article-title: Evidence-based public health: Moving beyond randomized trials
  publication-title: Amer. J. Public Health
  doi: 10.2105/AJPH.94.3.400
– volume: 10
  start-page: 1
  year: 1923
  ident: 10.1016/j.aam.2006.12.003_bib018
  article-title: Sur les applications de la théorie des probabilités aux experiences agricoles: Essai des principes
  publication-title: Roczniki Nauk Rolniczych
– year: 2006
  ident: 10.1016/j.aam.2006.12.003_bib011
– volume: 162
  start-page: 404
  year: 2005
  ident: 10.1016/j.aam.2006.12.003_bib020
  article-title: Combined postmenopausal hormone therapy and cardiovascular disease: Toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial
  publication-title: Amer. J. Epidemiology
  doi: 10.1093/aje/kwi223
– volume: 17
  start-page: 1863
  year: 1998
  ident: 10.1016/j.aam.2006.12.003_bib016
  article-title: Issues for covariance analysis of dichotomous and ordered categorical data from randomized clinical trials and non-parametric strategies for addressing them
  publication-title: Stat. Med.
  doi: 10.1002/(SICI)1097-0258(19980815/30)17:15/16<1863::AID-SIM989>3.0.CO;2-M
– volume: 99
  start-page: 779
  year: 1999
  ident: 10.1016/j.aam.2006.12.003_bib006
  article-title: Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: Final report of the Lyon Diet Heart Study
  publication-title: Circulation
  doi: 10.1161/01.CIR.99.6.779
– volume: 12
  start-page: 2351
  year: 1993
  ident: 10.1016/j.aam.2006.12.003_bib024
  article-title: Comparison of the Cox model and the regression tree procedure in analysing a randomized clinical trial
  publication-title: Stat. Med.
  doi: 10.1002/sim.4780122411
– volume: 8
  start-page: 945
  year: 1986
  ident: 10.1016/j.aam.2006.12.003_bib014
  article-title: Statistics and causal inference
  publication-title: J. Amer. Statist. Assoc.
  doi: 10.1080/01621459.1986.10478354
– volume: 61
  start-page: 899
  year: 2005
  ident: 10.1016/j.aam.2006.12.003_bib021
  article-title: Statistical issues arising in the Women's Health Initiative
  publication-title: Biometrics
  doi: 10.1111/j.0006-341X.2005.454_1.x
– volume: 22
  start-page: 3583
  year: 2003
  ident: 10.1016/j.aam.2006.12.003_bib017
  article-title: A note on non-parametric ANCOVA for covariate adjustment in randomized clinical trials
  publication-title: Stat. Med.
  doi: 10.1002/sim.1583
– volume: 7
  start-page: 484
  year: 1979
  ident: 10.1016/j.aam.2006.12.003_bib001
  article-title: Strong consistency of least squares estimates in dynamic models
  publication-title: Ann. Statist.
  doi: 10.1214/aos/1176344670
– year: 2004
  ident: 10.1016/j.aam.2006.12.003_bib003
– year: 2005
  ident: 10.1016/j.aam.2006.12.003_bib009
– volume: 288
  start-page: 321
  year: 2002
  ident: 10.1016/j.aam.2006.12.003_bib023
  article-title: Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
  publication-title: J. Amer. Med. Assoc.
  doi: 10.1001/jama.288.3.321
– year: 2003
  ident: 10.1016/j.aam.2006.12.003_bib012
– volume: 5
  start-page: 69
  year: 1978
  ident: 10.1016/j.aam.2006.12.003_bib013
  article-title: Sampling from a finite population: A remainder term estimate
  publication-title: Scand. J. Statist.
– volume: 9
  start-page: 1218
  year: 1981
  ident: 10.1016/j.aam.2006.12.003_bib008
  article-title: Bootstrapping regression models
  publication-title: Ann. Statist.
  doi: 10.1214/aos/1176345638
– volume: 30
  start-page: 691
  year: 2006
  ident: 10.1016/j.aam.2006.12.003_bib010
  article-title: Statistical models for causation: What inferential leverage do they provide?
  publication-title: Evaluation Review
  doi: 10.1177/0193841X06293771
– volume: 121
  start-page: 151
  year: 1999
  ident: 10.1016/j.aam.2006.12.003_bib022
  article-title: Association, causation, and marginal structural models
  publication-title: Synthese
  doi: 10.1023/A:1005285815569
– year: 2002
  ident: 10.1016/j.aam.2006.12.003_bib025
– volume: 17
  start-page: 309
  year: 1971
  ident: 10.1016/j.aam.2006.12.003_bib007
  article-title: Consistency of the least squares and Gauss–Markov estimators in regression models
  publication-title: Z. Wahrscheinlichkeitstheorie
  doi: 10.1007/BF00536301
SSID ssj0009263
Score 2.3285465
Snippet Regression adjustments are often made to experimental data. Since randomization does not justify the models, almost anything can happen. Here, we evaluate...
SourceID proquest
pascalfrancis
crossref
elsevier
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 180
SubjectTerms Balance
Exact sciences and technology
General mathematics
General, history and biography
Intention-to-treat
Mathematics
Multiple regression
Numerical analysis
Numerical analysis. Scientific computation
Randomization
Sciences and techniques of general use
Title On regression adjustments to experimental data
URI https://dx.doi.org/10.1016/j.aam.2006.12.003
https://www.proquest.com/docview/33574224
Volume 40
WOSCitedRecordID wos000253878000004&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
journalDatabaseRights – providerCode: PRVESC
  databaseName: Elsevier SD Freedom Collection Journals 2021
  customDbUrl:
  eissn: 1090-2074
  dateEnd: 20180131
  omitProxy: false
  ssIdentifier: ssj0009263
  issn: 0196-8858
  databaseCode: AIEXJ
  dateStart: 19950301
  isFulltext: true
  titleUrlDefault: https://www.sciencedirect.com
  providerName: Elsevier
link http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3fa9swED66dA8bY-xXWfaj80OfVhwsS5blxzA6tkHbQVvIm5FleTS0Tqid0j-_J0uyk5WWbbAXEUwcOfpOp7N0930Ae4mgOlEkDmWKs4mpFP0gmkHIRYVoK8IKWXZiE-nRkZjNsp9Oma7p5ATSuhY3N9nyv0KN1xBsUzr7F3D3P4oX8DOCji3Cju0fAX9sClR-2fTWel-W81XT2jo2DDM3CP1dXVofnE5tPkCXIStddHrZ07quFYrgiuc2TruU-P3pZGPzQPh8Y7-j5ataNpIuDWVOKISlVJ9o6xijLMJhtoo63nNaoiVnIfGaGyRWncmtqMRqIN5x1nbfYD6R8tKeCpl92YgOK1OfL3hiHsk8ETooE2XOHsF2nCaZGMH29PvB7MfAsxxb8Tz_F_xBdpfS91tH94Uiz5aywQlSWWWTO4t0F3mcvoDn7pUhmFqoX8KWrl_B08MBmNcwOa6DAfRgDfSgXQTroAcG9Ddw9vXg9Mu30ClhhIomog072kSudCFYhS1TnMc4kWRZUM0qkTLO0kzJpCAloZWWvCwp47SSgmtqGBl3YFQvav0WAl6Vht8IQ5JCsyJiRUIjxrKokhlTktExRH5QcuVo4o1ayUXu8wHnOY6jkS_lOYkNt-wYPve3LC1HykNfZn6kcxfk2eAtR7N46LbdDVT6joxVk5jwMXzyMOXoIc2xl6z1YtXklCYpw0j13b_1_B6eDDPnA4zaq5X-CI_VdXveXO06-7sFz5aJJQ
linkProvider Elsevier
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=On+regression+adjustments+to+experimental+data&rft.jtitle=Advances+in+applied+mathematics&rft.au=Freedman%2C+David+A.&rft.date=2008-02-01&rft.pub=Elsevier+Inc&rft.issn=0196-8858&rft.eissn=1090-2074&rft.volume=40&rft.issue=2&rft.spage=180&rft.epage=193&rft_id=info:doi/10.1016%2Fj.aam.2006.12.003&rft.externalDocID=S019688580700005X
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0196-8858&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0196-8858&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0196-8858&client=summon