Expression of interleukin-10 splicing variants is a positive prognostic feature in relapsed childhood acute lymphoblastic leukemia

Biologic features of hematologic malignancies have prognostic implications and are essential elements in the design of current therapeutic trials. This study aimed to determine the expression of a splicing-derived variant of interleukin (IL) -10 in leukemic cells and its clinical relevance in childr...

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Veröffentlicht in:	Journal of clinical oncology Jg. 23; H. 13; S. 3038
Hauptverfasser:	Wu, Shuling, Gessner, Reinhard, Taube, Tillmann, von Stackelberg, Arend, Henze, Günter, Seeger, Karl
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.05.2005
Schlagworte:	Adolescent Alternative Splicing Child Child, Preschool Female Gene Expression Profiling Genetic Variation Humans Immunoblotting Infant Interleukin-10 - genetics Male Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Prognosis Recurrence Retrospective Studies Reverse Transcriptase Polymerase Chain Reaction Treatment Outcome
ISSN:	0732-183X
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