Effect of intranasal insulin on perioperative cognitive function in older adults: a randomized, placebo-controlled, double-blind clinical trial

Postoperative cognitive impairment are common neural complications in older surgical patients and exacerbate the burden of medical care on families and society. A total of 140 older patients who were scheduled for elective orthopaedic surgery or pancreatic surgery with general anaesthesia were rando...

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Bibliographic Details
Published in:	Age and ageing Vol. 53; no. 9
Main Authors:	Sun, Miao, Ruan, Xianghan, Zhou, Zhikang, Huo, Yuting, Liu, Min, Liu, Siyuan, Cao, Jiangbei, Liu, Yan-Hong, Zhang, Xiaoying, Ma, Yu-Long, Mi, Weidong
Format:	Journal Article
Language:	English
Published:	England 01.09.2024
Subjects:	Administration, Intranasal Aged Aged, 80 and over Biomarkers - blood Cognition - drug effects Double-Blind Method Female Humans Hypoglycemic Agents - administration & dosage Hypoglycemic Agents - adverse effects Insulin - administration & dosage Male Mental Status and Dementia Tests Orthopedic Procedures - adverse effects Postoperative Cognitive Complications - diagnosis Postoperative Cognitive Complications - epidemiology Postoperative Cognitive Complications - etiology Postoperative Cognitive Complications - prevention & control Time Factors Treatment Outcome older people insulin resistance intranasal insulin older surgical patient postoperative cognitive function postoperative delirium (POD)
ISSN:	1468-2834, 1468-2834
Online Access:	Get more information
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