The effects of benzo(a)pyrene, nicotine, and tobacco-specific N-nitrosamines on the generation of human lymphokine-activated killer cells

The effects of four major components of snuff (fine-cut smokeless tobacco) on the development of lymphokine-activated killer cells (LAK) were measured in vitro. Of the components tested: nicotine, N'-nitrosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo(a)pyrene (BaP), on...

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Bibliographic Details

Published in:	Archives of oral biology Vol. 34; no. 4; p. 283
Main Authors:	Lindemann, R A, Park, N H
Format:	Journal Article
Language:	English
Published:	England 1989
Subjects:	Benzopyrenes - pharmacology Cytotoxicity, Immunologic DNA - biosynthesis Humans Killer Cells, Lymphokine-Activated - drug effects Killer Cells, Lymphokine-Activated - metabolism Lymphocyte Activation - drug effects Nicotine - pharmacology Nitrosamines - pharmacology Plants, Toxic Tobacco, Smokeless Tumor Cells, Cultured - drug effects
ISSN:	0003-9969
Online Access:	Get more information
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