The association of BRCA1 and BRCA2 mutations with prostate cancer risk, frequency, and mortality: A meta‐analysis

Background A prior meta‐analysis found no association between BRCA1 mutation and prostate cancer (PCa). Subsequent BRCA2 mutation studies have shown an association with PCa risk and mortality. We conducted a meta‐analysis of overall BRCA mutation carriers and in subgroups to (1) estimate PCa risk in...

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Bibliographic Details
Published in:	The Prostate Vol. 79; no. 8; pp. 880 - 895
Main Authors:	Oh, Mok, Alkhushaym, Nasser, Fallatah, Saad, Althagafi, Abdulhamid, Aljadeed, Rana, Alsowaida, Yazed, Jeter, Joanne, Martin, Jennifer R., Babiker, Hani M., McBride, Ali, Abraham, Ivo
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.06.2019
Subjects:	BRCA1 BRCA1 protein BRCA1 Protein - genetics BRCA2 BRCA2 protein BRCA2 Protein - genetics Breast cancer Case-Control Studies Cohort Studies Genes, BRCA1 Genes, BRCA2 Genotyping Humans Male Meta-analysis Mortality Mutation Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - mortality Statistical analysis Survival meta-analysis prostate cancer BRCA1 BRCA2
ISSN:	0270-4137, 1097-0045, 1097-0045
Online Access:	Get full text
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