IFNγ‐mediated repression of system xc− drives vulnerability to induced ferroptosis in hepatocellular carcinoma cells

IFNγ released from CD8+ T cells or natural killer cells plays a crucial role in antitumor host immunity. Several studies have found that IFNγ is involved in regulating tumor cell proliferation and apoptosis. However, few studies have examined its role in cell ferroptosis. Here, we found that IFNγ tr...

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Veröffentlicht in:Journal of leukocyte biology Jg. 110; H. 2; S. 301 - 314
Hauptverfasser: Kong, Rui, Wang, Nan, Han, Wei, Bao, Wen, Lu, Jie
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Bethesda Oxford University Press 01.08.2021
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ISSN:0741-5400, 1938-3673, 1938-3673
Online-Zugang:Volltext
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