The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril

Amyloids are ordered protein aggregates, found in all kingdoms of life, and are involved in aggregation diseases as well as in physiological activities. In microbes, functional amyloids are often key virulence determinants, yet the structural basis for their activity remains elusive. We determined t...

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Vydáno v:	Science (American Association for the Advancement of Science) Ročník 355; číslo 6327; s. 831
Hlavní autoři:	Tayeb-Fligelman, Einav, Tabachnikov, Orly, Moshe, Asher, Goldshmidt-Tran, Orit, Sawaya, Michael R, Coquelle, Nicolas, Colletier, Jacques-Philippe, Landau, Meytal
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 24.02.2017
Témata:	Amyloid - chemistry Amyloid - metabolism Bacterial Toxins - chemistry Bacterial Toxins - metabolism Cells, Cultured Crystallography, X-Ray Humans Protein Conformation Staphylococcus aureus - metabolism Staphylococcus aureus - pathogenicity T-Lymphocytes - microbiology
ISSN:	1095-9203, 1095-9203
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