Additive manufacturing of biomedical implants: A feasibility assessment via supply-chain cost analysis

The adoption of additive manufacturing (AM) for fabricating biomedical implants at hospitals provides many potential benefits. Relative to biomedical implants fabricated via traditional manufacturing (TM), typically available by suppliers out of the immediate region, biomedical implants fabricated t...

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Published in:Additive manufacturing Vol. 11; pp. 97 - 113
Main Authors: Emelogu, Adindu, Marufuzzaman, Mohammad, Thompson, Scott M., Shamsaei, Nima, Bian, Linkan
Format: Journal Article
Language:English
Published: Elsevier B.V 01.07.2016
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ISSN:2214-8604, 2214-7810
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Abstract The adoption of additive manufacturing (AM) for fabricating biomedical implants at hospitals provides many potential benefits. Relative to biomedical implants fabricated via traditional manufacturing (TM), typically available by suppliers out of the immediate region, biomedical implants fabricated through AM provides an opportunity to receive more patient-specific, customized parts with faster response, a lower inventory level, and reduced delivery costs. Despite the promising features of AM technologies, the make-or-buy decisions are not straightforward and require careful investigation due to the relatively high AM machine and production costs. Most of the existing studies focus on the analysis of process-level costs, which are usually evaluated/calculated based on individual AM processes. No research efforts, to the best of our knowledge, have been dedicated to the quantitative analysis of the costs of supply chains integrated with AM facilities, e.g., inventory cost, transportation cost, product lead time, etc. In this study, we propose a stochastic cost model to quantify the supply-chain level costs associated with the production of biomedical implants using AM techniques, and investigate the economic feasibility of using such technologies to fabricate biomedical implants at the sites of hospitals. The problem is formulated in the form of a stochastic programming model, which determines the number of AM facilities to be established and volume of product flow between manufacturing facilities and hospitals. A customized Sample Average Algorithm (SAA) is developed to obtain the solutions. We apply the cost model to a real-world case study that focuses on the use of biomedical implants for hospitals in the state of Mississippi (MS), and identify the conditions and cost parameters that have significant impact on the economic feasibility of AM. We find that the ratio between the unit production costs of AM and TM (ATR), as well as product lead time and demands, are key cost parameters that determine the economic feasibility of AM.
AbstractList The adoption of additive manufacturing (AM) for fabricating biomedical implants at hospitals provides many potential benefits. Relative to biomedical implants fabricated via traditional manufacturing (TM), typically available by suppliers out of the immediate region, biomedical implants fabricated through AM provides an opportunity to receive more patient-specific, customized parts with faster response, a lower inventory level, and reduced delivery costs. Despite the promising features of AM technologies, the make-or-buy decisions are not straightforward and require careful investigation due to the relatively high AM machine and production costs. Most of the existing studies focus on the analysis of process-level costs, which are usually evaluated/calculated based on individual AM processes. No research efforts, to the best of our knowledge, have been dedicated to the quantitative analysis of the costs of supply chains integrated with AM facilities, e.g., inventory cost, transportation cost, product lead time, etc. In this study, we propose a stochastic cost model to quantify the supply-chain level costs associated with the production of biomedical implants using AM techniques, and investigate the economic feasibility of using such technologies to fabricate biomedical implants at the sites of hospitals. The problem is formulated in the form of a stochastic programming model, which determines the number of AM facilities to be established and volume of product flow between manufacturing facilities and hospitals. A customized Sample Average Algorithm (SAA) is developed to obtain the solutions. We apply the cost model to a real-world case study that focuses on the use of biomedical implants for hospitals in the state of Mississippi (MS), and identify the conditions and cost parameters that have significant impact on the economic feasibility of AM. We find that the ratio between the unit production costs of AM and TM (ATR), as well as product lead time and demands, are key cost parameters that determine the economic feasibility of AM.
Author Emelogu, Adindu
Bian, Linkan
Marufuzzaman, Mohammad
Shamsaei, Nima
Thompson, Scott M.
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  surname: Emelogu
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  givenname: Mohammad
  surname: Marufuzzaman
  fullname: Marufuzzaman, Mohammad
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  givenname: Scott M.
  surname: Thompson
  fullname: Thompson, Scott M.
  organization: Department of Mechanical Engineering, Mississippi State University, MS 39762, USA
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  surname: Shamsaei
  fullname: Shamsaei, Nima
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  givenname: Linkan
  surname: Bian
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  email: bian@ise.msstate.edu
  organization: Analytics and Optimization Laboratory, Department of Industrial and Systems Engineering, Mississippi State University, MS 39762, USA
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Additive manufacturing
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Cost analysis
Biomedical implants
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Snippet The adoption of additive manufacturing (AM) for fabricating biomedical implants at hospitals provides many potential benefits. Relative to biomedical implants...
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SubjectTerms Additive manufacturing
Biomedical implants
Cost analysis
Stochastic programming model
Supply chain
Title Additive manufacturing of biomedical implants: A feasibility assessment via supply-chain cost analysis
URI https://dx.doi.org/10.1016/j.addma.2016.04.006
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