Lupin kernel fiber consumption modifies fecal microbiota in healthy men as determined by rRNA gene fluorescent in situ hybridization

Changes in the composition of gastrointestinal microbiota by dietary interventions using pro- and prebiotics provide opportunity for improving health and preventing disease. However, the capacity of lupin kernel fiber (LKFibre), a novel legume-derived food ingredient, to act as a prebiotic and modul...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of nutrition Jg. 45; H. 6; S. 335 - 341
Hauptverfasser:	Smith, Stuart C., Choy, Rachel, Johnson, Stuart K., Hall, Ramon S., Wildeboer-Veloo, Alida C.M., Welling, Gjalt W.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Heidelberg Springer 01.09.2006 Springer Nature B.V
Schlagworte:	Adult Bifidobacterium - growth & development Bifidobacterium - metabolism Biological and medical sciences Clostridium - growth & development Clostridium - metabolism Colon - microbiology Cross-Over Studies Dietary Fiber - administration & dosage Feces - microbiology Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Humans In Situ Hybridization, Fluorescence - methods Lupinus - chemistry Male Middle Aged Probiotics RNA, Ribosomal, 16S - metabolism Single-Blind Method Vertebrates: anatomy and physiology, studies on body, several organs or systems Human Actinomycetaceae Nutrition human diet Lupin Microflora prebiotic Feeding Prebiotics Actinomycetales fecal microbiota Diet Food intake FISH Bacteria Actinomycetes Feces Dietary fiber Bifidobacterium bifidum lupin kernel fiber
ISSN:	1436-6207, 1436-6215
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Abstract	Changes in the composition of gastrointestinal microbiota by dietary interventions using pro- and prebiotics provide opportunity for improving health and preventing disease. However, the capacity of lupin kernel fiber (LKFibre), a novel legume-derived food ingredient, to act as a prebiotic and modulate the colonic microbiota in humans needed investigation. The present study aimed to determine the effect of LKFibre on human intestinal microbiota by quantitative fluorescent in situ hybridization (FISH) analysis. A total of 18 free-living healthy males between the ages of 24 and 64 years consumed a control diet and a LKFibre diet (containing an additional 17-30 g/day fiber beyond that of the control-incorporated into daily food items) for 28 days with a 28-day washout period in a single-blind, randomized, crossover dietary intervention design. Fecal samples were collected for 3 days towards the end of each diet and microbial populations analyzed by FISH analysis using 16S rRNA gene-based oligonucleotide probes targeting total and predominant microbial populations. Significantly higher levels of Bifidobacterium spp. (P = 0.001) and significantly lower levels of the clostridia group of C. ramosum, C. spiroforme and C. cocleatum (P = 0.039) were observed on the LKFibre diet compared with the control. No significant differences between the LKFibre and the control diet were observed for total bacteria, Lactobacillus spp., the Eubacterium spp., the C. histolyticum/C. lituseburense group and the Bacteroides-Prevotella group. Ingestion of LKFibre stimulated colonic bifidobacteria growth, which suggests that this dietary fiber may be considered as a prebiotic and may beneficially contribute to colon health.
AbstractList	Changes in the composition of gastrointestinal microbiota by dietary interventions using pro- and prebiotics provide opportunity for improving health and preventing disease. However, the capacity of lupin kernel fiber (LKFibre), a novel legume-derived food ingredient, to act as a prebiotic and modulate the colonic microbiota in humans needed investigation. The present study aimed to determine the effect of LKFibre on human intestinal microbiota by quantitative fluorescent in situ hybridization (FISH) analysis. A total of 18 free-living healthy males between the ages of 24 and 64 years consumed a control diet and a LKFibre diet (containing an additional 17-30 g/day fiber beyond that of the control-incorporated into daily food items) for 28 days with a 28-day washout period in a single-blind, randomized, crossover dietary intervention design. Fecal samples were collected for 3 days towards the end of each diet and microbial populations analyzed by FISH analysis using 16S rRNA gene-based oligonucleotide probes targeting total and predominant microbial populations. Significantly higher levels of Bifidobacterium spp. (P = 0.001) and significantly lower levels of the clostridia group of C. ramosum, C. spiroforme and C. cocleatum (P = 0.039) were observed on the LKFibre diet compared with the control. No significant differences between the LKFibre and the control diet were observed for total bacteria, Lactobacillus spp., the Eubacterium spp., the C. histolyticum/C. lituseburense group and the Bacteroides-Prevotella group. Ingestion of LKFibre stimulated colonic bifidobacteria growth, which suggests that this dietary fiber may be considered as a prebiotic and may beneficially contribute to colon health. Changes in the composition of gastrointestinal microbiota by dietary interventions using pro- and prebiotics provide opportunity for improving health and preventing disease. However, the capacity of lupin kernel fiber (LKFibre), a novel legume-derived food ingredient, to act as a prebiotic and modulate the colonic microbiota in humans needed investigation.BACKGROUNDChanges in the composition of gastrointestinal microbiota by dietary interventions using pro- and prebiotics provide opportunity for improving health and preventing disease. However, the capacity of lupin kernel fiber (LKFibre), a novel legume-derived food ingredient, to act as a prebiotic and modulate the colonic microbiota in humans needed investigation.The present study aimed to determine the effect of LKFibre on human intestinal microbiota by quantitative fluorescent in situ hybridization (FISH) analysis.AIM OF THE STUDYThe present study aimed to determine the effect of LKFibre on human intestinal microbiota by quantitative fluorescent in situ hybridization (FISH) analysis.A total of 18 free-living healthy males between the ages of 24 and 64 years consumed a control diet and a LKFibre diet (containing an additional 17-30 g/day fiber beyond that of the control-incorporated into daily food items) for 28 days with a 28-day washout period in a single-blind, randomized, crossover dietary intervention design.DESIGNA total of 18 free-living healthy males between the ages of 24 and 64 years consumed a control diet and a LKFibre diet (containing an additional 17-30 g/day fiber beyond that of the control-incorporated into daily food items) for 28 days with a 28-day washout period in a single-blind, randomized, crossover dietary intervention design.Fecal samples were collected for 3 days towards the end of each diet and microbial populations analyzed by FISH analysis using 16S rRNA gene-based oligonucleotide probes targeting total and predominant microbial populations.METHODSFecal samples were collected for 3 days towards the end of each diet and microbial populations analyzed by FISH analysis using 16S rRNA gene-based oligonucleotide probes targeting total and predominant microbial populations.Significantly higher levels of Bifidobacterium spp. (P = 0.001) and significantly lower levels of the clostridia group of C. ramosum, C. spiroforme and C. cocleatum (P = 0.039) were observed on the LKFibre diet compared with the control. No significant differences between the LKFibre and the control diet were observed for total bacteria, Lactobacillus spp., the Eubacterium spp., the C. histolyticum/C. lituseburense group and the Bacteroides-Prevotella group.RESULTSSignificantly higher levels of Bifidobacterium spp. (P = 0.001) and significantly lower levels of the clostridia group of C. ramosum, C. spiroforme and C. cocleatum (P = 0.039) were observed on the LKFibre diet compared with the control. No significant differences between the LKFibre and the control diet were observed for total bacteria, Lactobacillus spp., the Eubacterium spp., the C. histolyticum/C. lituseburense group and the Bacteroides-Prevotella group.Ingestion of LKFibre stimulated colonic bifidobacteria growth, which suggests that this dietary fiber may be considered as a prebiotic and may beneficially contribute to colon health.CONCLUSIONSIngestion of LKFibre stimulated colonic bifidobacteria growth, which suggests that this dietary fiber may be considered as a prebiotic and may beneficially contribute to colon health. Changes in the composition of gastrointestinal microbiota by dietary interventions using pro- and prebiotics provide opportunity for improving health and preventing disease. However, the capacity of lupin kernel fiber (LKFibre), a novel legume-derived food ingredient, to act as a prebiotic and modulate the colonic microbiota in humans needed investigation. The present study aimed to determine the effect of LKFibre on human intestinal microbiota by quantitative fluorescent in situ hybridization (FISH) analysis. A total of 18 free-living healthy males between the ages of 24 and 64 years consumed a control diet and a LKFibre diet (containing an additional 17-30 g/day fiber beyond that of the control-incorporated into daily food items) for 28 days with a 28-day washout period in a single-blind, randomized, crossover dietary intervention design. Fecal samples were collected for 3 days towards the end of each diet and microbial populations analyzed by FISH analysis using 16S rRNA gene-based oligonucleotide probes targeting total and predominant microbial populations. Significantly higher levels of Bifidobacterium spp. (P = 0.001) and significantly lower levels of the clostridia group of C. ramosum, C. spiroforme and C. cocleatum (P = 0.039) were observed on the LKFibre diet compared with the control. No significant differences between the LKFibre and the control diet were observed for total bacteria, Lactobacillus spp., the Eubacterium spp., the C. histolyticum/C. lituseburense group and the Bacteroides-Prevotella group. Ingestion of LKFibre stimulated colonic bifidobacteria growth, which suggests that this dietary fiber may be considered as a prebiotic and may beneficially contribute to colon health.
Author	Choy, Rachel Johnson, Stuart K. Welling, Gjalt W. Smith, Stuart C. Hall, Ramon S. Wildeboer-Veloo, Alida C.M.
Author_xml	– sequence: 1 givenname: Stuart C. surname: Smith fullname: Smith, Stuart C. – sequence: 2 givenname: Rachel surname: Choy fullname: Choy, Rachel – sequence: 3 givenname: Stuart K. surname: Johnson fullname: Johnson, Stuart K. – sequence: 4 givenname: Ramon S. surname: Hall fullname: Hall, Ramon S. – sequence: 5 givenname: Alida C.M. surname: Wildeboer-Veloo fullname: Wildeboer-Veloo, Alida C.M. – sequence: 6 givenname: Gjalt W. surname: Welling fullname: Welling, Gjalt W.
BackLink	http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18093035$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/16763747$$D View this record in MEDLINE/PubMed
BookMark	eNp9kc1v1DAQxS3Uin7AH8AFWUhwSxnHiZMcq4ovaVUkBGfLdsasS2IvtnNYzvzhOOxCpR56mjn83rzRexfkxAePhLxgcMUAurcJgA9NBSAqEMAr9oScs4aLStSsPfm_Q3dGLlK6A4CaC_aUnDHRCd413Tn5vVl2ztMfGD1O1DqNkZrg0zLvsguezmF01mGiFo2a6OxMDNqFrGhRbVFNebunM3qqEh0xY5ydx5HqPY1fbq_pd_RI7bSEiMmgz6squbzQ7V5HN7pfanV5Rk6tmhI-P85L8u39u683H6vN5w-fbq43leGtyJXWrLEj6n4wWhloGXDVqbE1IISpeyGYam1BONRWNbzVomGqFkPLBoR2RH5J3hzu7mL4uWDKcnblrWlSHsOSpOj7RtTNUMBXD8C7sERffpM1a_quOLACvTxCi55xlLvoZhX38l-4BXh9BFQq4dmovHHpnuth4MDbwrEDV7JNKaK9R0CuRctD0bIULdei5WrePdAYl_-GmaNy0yPKPznOrTE
CitedBy_id	crossref_primary_10_3390_molecules26082395 crossref_primary_10_1016_j_foodchem_2020_126238 crossref_primary_10_1093_ajcn_nqy041 crossref_primary_10_1016_j_indcrop_2015_06_028 crossref_primary_10_1111_jam_14424 crossref_primary_10_1016_j_foodchem_2018_02_111 crossref_primary_10_1111_j_1574_6941_2011_01155_x crossref_primary_10_1111_1574_6941_12157 crossref_primary_10_1016_j_jprot_2016_04_033 crossref_primary_10_1186_1475_2891_12_101 crossref_primary_10_17221_252_2009_CJFS crossref_primary_10_1016_j_appet_2010_06_004 crossref_primary_10_3390_jpm10040175 crossref_primary_10_1039_C7FO00302A crossref_primary_10_1016_j_tifs_2023_104281 crossref_primary_10_1016_j_aquaculture_2013_11_011 crossref_primary_10_1016_j_fbio_2018_10_008 crossref_primary_10_1016_j_foodchem_2011_11_145 crossref_primary_10_1016_j_tins_2019_08_006 crossref_primary_10_1016_j_ajcnut_2025_06_026 crossref_primary_10_1017_S0029665113000025 crossref_primary_10_1016_j_anifeedsci_2016_08_026 crossref_primary_10_3390_nu14142845 crossref_primary_10_1080_19490976_2024_2350785 crossref_primary_10_3390_molecules27238557 crossref_primary_10_1080_10408398_2013_814044 crossref_primary_10_3390_nu8120779 crossref_primary_10_2337_dc15_0628 crossref_primary_10_1007_s13205_012_0044_x crossref_primary_10_1016_j_clnesp_2024_06_051 crossref_primary_10_3920_QAS2012_0189 crossref_primary_10_1016_j_chempr_2023_02_021 crossref_primary_10_1007_s10620_020_06106_8 crossref_primary_10_3390_nu14020327 crossref_primary_10_1016_j_jafr_2025_101926 crossref_primary_10_1016_j_heliyon_2023_e20503 crossref_primary_10_1128_msystems_00115_21 crossref_primary_10_3389_fpls_2019_01385 crossref_primary_10_1002_jsfa_6249 crossref_primary_10_3945_jn_109_108191 crossref_primary_10_1016_j_ejbt_2014_07_004 crossref_primary_10_1080_10408398_2024_2434725 crossref_primary_10_3920_QAS2013_0347 crossref_primary_10_3389_fmolb_2022_1038830 crossref_primary_10_1097_MPG_0000000000000443 crossref_primary_10_3390_molecules27185947 crossref_primary_10_3389_fagro_2021_661295 crossref_primary_10_3390_microorganisms8030379 crossref_primary_10_3390_nu17111749 crossref_primary_10_1111_j_1574_6941_2008_00527_x
Cites_doi	10.1006/anae.2001.0368 10.1080/089106001750462669 10.1111/j.1365-2621.2002.tb11410.x 10.3109/08910609509140086 10.1046/j.1467-3010.2000.00050.x 10.1093/ajcn/69.5.1052s 10.1080/089106099435754 10.1079/BJN2001394 10.1038/sj.ejcn.1602077 10.1136/gut.2003.037580 10.1099/00207713-44-4-812 10.1079/NRR200479 10.1002/jsfa.2740610209 10.1128/IAI.62.11.5191-5194.1994 10.1016/0016-5085(95)90192-2 10.1016/S0271-5317(01)00284-6 10.1093/jn/131.6.1862 10.1128/AEM.64.9.3336-3345.1998 10.1080/08910600310018823 10.1128/AEM.68.6.2982-2990.2002 10.1079/BJN20051648 10.1097/00005176-200001000-00019 10.1111/j.1365-2672.1994.tb03443.x 10.1078/072320203322337399
ContentType	Journal Article
Copyright	2006 INIST-CNRS Steinkopff Verlag Darmstadt 2006
Copyright_xml	– notice: 2006 INIST-CNRS – notice: Steinkopff Verlag Darmstadt 2006
DBID	AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 3V. 7QP 7RQ 7RV 7TS 7X7 7XB 88E 8AO 8C1 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH K9- K9. KB0 M0R M0S M1P NAPCQ PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS Q9U 7X8
DOI	10.1007/s00394-006-0603-1
DatabaseName	CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Calcium & Calcified Tissue Abstracts Career & Technical Education Database ProQuest Nursing & Allied Health Database Physical Education Index Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Public Health Database Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) Consumer Health Database ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) ProQuest Consumer Health Database ProQuest Health & Medical Collection Medical Database Nursing & Allied Health Premium ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Pharma Collection ProQuest Family Health (Alumni Edition) ProQuest Central China Physical Education Index ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Public Health ProQuest Central Basic ProQuest Family Health ProQuest One Academic Eastern Edition ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Career and Technical Education ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic
DatabaseTitleList	ProQuest One Academic Middle East (New) MEDLINE - Academic MEDLINE
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7RV name: Nursing & Allied Health Database url: https://search.proquest.com/nahs sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Anatomy & Physiology Diet & Clinical Nutrition
EISSN	1436-6215
EndPage	341
ExternalDocumentID	1130793261 16763747 18093035 10_1007_s00394_006_0603_1
Genre	Randomized Controlled Trial Research Support, Non-U.S. Gov't Journal Article
GroupedDBID	--- -Y2 -~C .86 .VR 04C 06C 06D 0R~ 0VY 1N0 2.D 203 29G 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2QV 2VQ 2~H 30V 36B 4.4 406 408 409 40D 40E 53G 5GY 5VS 67Z 6NX 6PF 7RQ 7RV 7X7 88E 8AO 8C1 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X A8Z AABHQ AACDK AAHBH AAHNG AAIAL AAIKT AAJBT AAJKR AANZL AAPKM AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAWTL AAYIU AAYQN AAYTO AAYXX ABAKF ABBBX ABBRH ABBXA ABDBE ABDBF ABDZT ABECU ABFSG ABFTV ABHLI ABHQN ABJNI ABJOX ABKCH ABKTR ABMNI ABMQK ABNWP ABQBU ABQSL ABRTQ ABSXP ABTEG ABTHY ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACAOD ACBXY ACDTI ACGFS ACHSB ACHXU ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACPRK ACSNA ACSTC ACUHS ACZOJ ADBBV ADHIR ADHKG ADIMF ADKNI ADKPE ADOJX ADPHR ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AETLH AEVLU AEXYK AEZWR AFBBN AFDZB AFEXP AFFHD AFGCZ AFHIU AFKRA AFLOW AFOHR AFQWF AFWTZ AFZKB AGAYW AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGQPQ AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHKAY AHMBA AHPBZ AHSBF AHWEU AHYZX AIAKS AIGIU AIIXL AILAN AITGF AIXLP AJBLW AJRNO AJZVZ ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AOCGG ARMRJ ASPBG ATHPR AVWKF AXYYD AYFIA AYJHY AZFZN AZQEC B-. B0M BA0 BDATZ BENPR BGNMA BKEYQ BKNYI BMSDO BPHCQ BSONS BVXVI CAG CCPQU CITATION COF CS3 CSCUP DDRTE DL5 DNIVK DPUIP DU5 DWQXO DXH EAD EAP EAS EBB EBC EBD EBLON EBS EBX ECF ECGQY ECT EHN EIHBH EIOEI EJD EMB EMK EMOBN EPL EPT ESBYG ESTFP ESX EX3 F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ7 GQ8 GXS H13 HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ IHE IJ- IKXTQ ITM IWAJR IXC IXE IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ K9- KDC KOV LAS LLZTM M0R M1P M4Y MA- N2Q N9A NAPCQ NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM P19 P9N PCD PF0 PHGZM PHGZT PJZUB PPXIY PQQKQ PROAC PSQYO PT4 PT5 Q2X QOR QOS Q~Q R89 R9I RNI ROL RPX RRX RSV RZK S16 S1Z S26 S27 S28 S3B SAP SCLPG SCM SDH SHX SISQX SJYHP SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW STPWE SV3 SZN T13 T16 TSG TSK TSV TUC TUS U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WJK WK8 WOW Y6R YLTOR Z45 ZMTXR ~8M ~KM AAYZH AESKC ALIPV IQODW RIG CGR CUY CVF ECM EIF NPM 3V. 7QP 7TS 7XB 8FK K9. PKEHL PQEST PQUKI PRINS Q9U 7X8
ID	FETCH-LOGICAL-c356t-bb14fdeb89cbac05103a7ad5c066c28661a5f14f302fa435b641a269519e05de3
IEDL.DBID	BENPR
ISICitedReferencesCount	64
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000240482400004&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	1436-6207
IngestDate	Sun Nov 09 09:52:08 EST 2025 Tue Dec 02 15:57:52 EST 2025 Fri Dec 05 04:53:20 EST 2025 Mon Jul 21 09:16:38 EDT 2025 Sat Nov 29 04:10:27 EST 2025 Tue Nov 18 21:49:37 EST 2025
IsPeerReviewed	true
IsScholarly	true
Issue	6
Keywords	Human Actinomycetaceae Nutrition human diet Lupin Microflora prebiotic Feeding Prebiotics Actinomycetales fecal microbiota Diet Food intake FISH Bacteria Actinomycetes Feces Dietary fiber Bifidobacterium bifidum lupin kernel fiber
Language	English
License	http://www.springer.com/tdm CC BY 4.0
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c356t-bb14fdeb89cbac05103a7ad5c066c28661a5f14f302fa435b641a269519e05de3
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Undefined-3
PMID	16763747
PQID	214873021
PQPubID	34175
PageCount	7
ParticipantIDs	proquest_miscellaneous_68846249 proquest_journals_214873021 pubmed_primary_16763747 pascalfrancis_primary_18093035 crossref_primary_10_1007_s00394_006_0603_1 crossref_citationtrail_10_1007_s00394_006_0603_1
PublicationCentury	2000
PublicationDate	2006-09-01
PublicationDateYYYYMMDD	2006-09-01
PublicationDate_xml	– month: 09 year: 2006 text: 2006-09-01 day: 01
PublicationDecade	2000
PublicationPlace	Heidelberg
PublicationPlace_xml	– name: Heidelberg – name: Germany
PublicationTitle	European journal of nutrition
PublicationTitleAlternate	Eur J Nutr
PublicationYear	2006
Publisher	Springer Springer Nature B.V
Publisher_xml	– name: Springer – name: Springer Nature B.V
References	HJM Harmsen (603_CR7) 2003; 14 AJ Evans (603_CR11) 1993; 61 HJ Harmsen (603_CR5) 2000; 30 ACM Wildeboer-Veloo (603_CR16) 2003; 15 RS Hall (603_CR10) 2005; 59 GR Gibson (603_CR19) 1994; 77 S Kolida (603_CR1) 2000; 25 VJ McCracken (603_CR8) 2001; 131 EG Zoetendal (603_CR22) 2001; 13 MD Collins (603_CR3) 1999; 69 LKL Poulsen (603_CR14) 1994; 62 HJM Harmsen (603_CR15) 2002; 68 VA Rao (603_CR4) 2001; 21 RL Clark (603_CR9) 2002; 67 L Gois-Rigottier (603_CR25) 2003; 26 SJ Langlands (603_CR20) 2005; 53 MD Collins (603_CR13) 1994; 44 S Pathmakanthan (603_CR18) 1999; 11 LA Rubio (603_CR21) 1995; 8 SK Johnson (603_CR24) 2006; 95 KM Tuohy (603_CR6) 2001a; 7 AH Franks (603_CR12) 1998; 64 KM Tuohy (603_CR23) 2001; 86 GR Gibson (603_CR17) 1995; 108 GR Gibson (603_CR2) 2004; 17 11570986 - Br J Nutr. 2001 Sep;86(3):341-8 11385080 - J Nutr. 2001 Jun;131(6):1862-70 7698613 - Gastroenterology. 1995 Apr;108(4):975-82 15479681 - Gut. 2004 Nov;53(11):1610-6 16469156 - Br J Nutr. 2006 Feb;95(2):372-8 12039758 - Appl Environ Microbiol. 2002 Jun;68(6):2982-90 7927805 - Infect Immun. 1994 Nov;62(11):5191-4 7981107 - Int J Syst Bacteriol. 1994 Oct;44(4):812-26 7989269 - J Appl Bacteriol. 1994 Oct;77(4):412-20 19079930 - Nutr Res Rev. 2004 Dec;17(2):259-75 9726880 - Appl Environ Microbiol. 1998 Sep;64(9):3336-45 10232648 - Am J Clin Nutr. 1999 May;69(5):1052S-1057S 12747418 - Syst Appl Microbiol. 2003 Mar;26(1):110-8 10630441 - J Pediatr Gastroenterol Nutr. 2000 Jan;30(1):61-7 15508014 - Eur J Clin Nutr. 2005 Mar;59(3):325-33
References_xml	– volume: 7 start-page: 113 year: 2001a ident: 603_CR6 publication-title: Anaerobe doi: 10.1006/anae.2001.0368 – volume: 13 start-page: 129 year: 2001 ident: 603_CR22 publication-title: Microbial Ecol Health Dis doi: 10.1080/089106001750462669 – volume: 67 start-page: 356 year: 2002 ident: 603_CR9 publication-title: J Food Sci doi: 10.1111/j.1365-2621.2002.tb11410.x – volume: 14 start-page: 211 year: 2003 ident: 603_CR7 publication-title: Microb Ecol Health Dis – volume: 8 start-page: 101 year: 1995 ident: 603_CR21 publication-title: Microb Ecol Health Dis doi: 10.3109/08910609509140086 – volume: 25 start-page: 223 year: 2000 ident: 603_CR1 publication-title: Nutr Bull doi: 10.1046/j.1467-3010.2000.00050.x – volume: 69 start-page: 1052S year: 1999 ident: 603_CR3 publication-title: Am J Clin Nutr doi: 10.1093/ajcn/69.5.1052s – volume: 11 start-page: 169 year: 1999 ident: 603_CR18 publication-title: Microbial Ecol Health Dis doi: 10.1080/089106099435754 – volume: 86 start-page: 341 year: 2001 ident: 603_CR23 publication-title: Br J Nutr doi: 10.1079/BJN2001394 – volume: 59 start-page: 325 year: 2005 ident: 603_CR10 publication-title: Eur J Clin Nutr doi: 10.1038/sj.ejcn.1602077 – volume: 53 start-page: 1610 year: 2005 ident: 603_CR20 publication-title: Gut doi: 10.1136/gut.2003.037580 – volume: 44 start-page: 812 year: 1994 ident: 603_CR13 publication-title: Int J Syst Bacteriol doi: 10.1099/00207713-44-4-812 – volume: 17 start-page: 259 year: 2004 ident: 603_CR2 publication-title: Nutr Res Rev doi: 10.1079/NRR200479 – volume: 61 start-page: 189 year: 1993 ident: 603_CR11 publication-title: J Sci Food Agric doi: 10.1002/jsfa.2740610209 – volume: 62 start-page: 5191 year: 1994 ident: 603_CR14 publication-title: Infect Immun doi: 10.1128/IAI.62.11.5191-5194.1994 – volume: 108 start-page: 975 year: 1995 ident: 603_CR17 publication-title: Gastroenterol doi: 10.1016/0016-5085(95)90192-2 – volume: 21 start-page: 843 year: 2001 ident: 603_CR4 publication-title: Nutr Res doi: 10.1016/S0271-5317(01)00284-6 – volume: 131 start-page: 1862 year: 2001 ident: 603_CR8 publication-title: J Nutr doi: 10.1093/jn/131.6.1862 – volume: 64 start-page: 3336 year: 1998 ident: 603_CR12 publication-title: Appl Environ Microbiol doi: 10.1128/AEM.64.9.3336-3345.1998 – volume: 15 start-page: 131 year: 2003 ident: 603_CR16 publication-title: Microb Ecol Health Dis doi: 10.1080/08910600310018823 – volume: 68 start-page: 2982 year: 2002 ident: 603_CR15 publication-title: Appl Environ Microbiol doi: 10.1128/AEM.68.6.2982-2990.2002 – volume: 95 start-page: 372 year: 2006 ident: 603_CR24 publication-title: Br J Nutr doi: 10.1079/BJN20051648 – volume: 30 start-page: 61 year: 2000 ident: 603_CR5 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/00005176-200001000-00019 – volume: 77 start-page: 412 year: 1994 ident: 603_CR19 publication-title: J Appl Bacteriol doi: 10.1111/j.1365-2672.1994.tb03443.x – volume: 26 start-page: 110 year: 2003 ident: 603_CR25 publication-title: Syst Appl Micr doi: 10.1078/072320203322337399 – reference: 16469156 - Br J Nutr. 2006 Feb;95(2):372-8 – reference: 12747418 - Syst Appl Microbiol. 2003 Mar;26(1):110-8 – reference: 11385080 - J Nutr. 2001 Jun;131(6):1862-70 – reference: 10630441 - J Pediatr Gastroenterol Nutr. 2000 Jan;30(1):61-7 – reference: 7698613 - Gastroenterology. 1995 Apr;108(4):975-82 – reference: 10232648 - Am J Clin Nutr. 1999 May;69(5):1052S-1057S – reference: 15508014 - Eur J Clin Nutr. 2005 Mar;59(3):325-33 – reference: 15479681 - Gut. 2004 Nov;53(11):1610-6 – reference: 19079930 - Nutr Res Rev. 2004 Dec;17(2):259-75 – reference: 11570986 - Br J Nutr. 2001 Sep;86(3):341-8 – reference: 9726880 - Appl Environ Microbiol. 1998 Sep;64(9):3336-45 – reference: 7981107 - Int J Syst Bacteriol. 1994 Oct;44(4):812-26 – reference: 7989269 - J Appl Bacteriol. 1994 Oct;77(4):412-20 – reference: 12039758 - Appl Environ Microbiol. 2002 Jun;68(6):2982-90 – reference: 7927805 - Infect Immun. 1994 Nov;62(11):5191-4
SSID	ssj0002361
Score	2.0433466
Snippet	Changes in the composition of gastrointestinal microbiota by dietary interventions using pro- and prebiotics provide opportunity for improving health and...
SourceID	proquest pubmed pascalfrancis crossref
SourceType	Aggregation Database Index Database Enrichment Source
StartPage	335
SubjectTerms	Adult Bifidobacterium - growth & development Bifidobacterium - metabolism Biological and medical sciences Clostridium - growth & development Clostridium - metabolism Colon - microbiology Cross-Over Studies Dietary Fiber - administration & dosage Feces - microbiology Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Humans In Situ Hybridization, Fluorescence - methods Lupinus - chemistry Male Middle Aged Probiotics RNA, Ribosomal, 16S - metabolism Single-Blind Method Vertebrates: anatomy and physiology, studies on body, several organs or systems
Title	Lupin kernel fiber consumption modifies fecal microbiota in healthy men as determined by rRNA gene fluorescent in situ hybridization
URI	https://www.ncbi.nlm.nih.gov/pubmed/16763747 https://www.proquest.com/docview/214873021 https://www.proquest.com/docview/68846249
Volume	45
WOSCitedRecordID	wos000240482400004&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVPQU databaseName: Career & Technical Education Database (ProQuest) customDbUrl: eissn: 1436-6215 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0002361 issn: 1436-6207 databaseCode: 7RQ dateStart: 19990101 isFulltext: true titleUrlDefault: https://search.proquest.com/career providerName: ProQuest – providerCode: PRVPQU databaseName: Consumer Health Database customDbUrl: eissn: 1436-6215 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0002361 issn: 1436-6207 databaseCode: M0R dateStart: 19990101 isFulltext: true titleUrlDefault: https://search.proquest.com/familyhealth providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1436-6215 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0002361 issn: 1436-6207 databaseCode: 7X7 dateStart: 19990101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: Nursing & Allied Health Database customDbUrl: eissn: 1436-6215 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0002361 issn: 1436-6207 databaseCode: 7RV dateStart: 19990101 isFulltext: true titleUrlDefault: https://search.proquest.com/nahs providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1436-6215 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0002361 issn: 1436-6207 databaseCode: BENPR dateStart: 19990101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Public Health Database customDbUrl: eissn: 1436-6215 dateEnd: 20171231 omitProxy: false ssIdentifier: ssj0002361 issn: 1436-6207 databaseCode: 8C1 dateStart: 19990101 isFulltext: true titleUrlDefault: https://search.proquest.com/publichealth providerName: ProQuest – providerCode: PRVAVX databaseName: SpringerLINK Contemporary 1997-Present customDbUrl: eissn: 1436-6215 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0002361 issn: 1436-6207 databaseCode: RSV dateStart: 19990101 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9NAEB7RlAMS4tHyMIWwB8QBycLPXfuEQmnFAaISoMrN2qewSOwQJ0i588OZXW9c9UAvXEbyYyw_xrPf7M58A_AqKTOeMRGHsUpNmDGtQ5GWachEmuaFUpnKuWs2wabTYj4vL3xuTufTKvc-0Tlq1Uo7R_42QdyO1pjE71a_Qts0yi6u-g4aB3BoicqyERy-P5tezAZXbJlFXHlRSkOaRGy_rBk5FtHUsuLagJra_KxrA9PdFe_wHZm-ucW_0acbhc7v_-f9P4B7Hn6SSW8vD-GWbo7geNJg6L3ckdfEJYS6mfYjCD7UeoP7PHXogkz3zP3H8OfTdlU35KdeN3pBjE07IdJVczoXRJatqg0G4cRoq7mse76nDSeo1dde7shSN4R3RPmMHK2I2JH1bDohaNWamMW2XfdsU1YLn2RLfuxshZmvHX0E38_Pvp1-DH1Dh1CmOd2EQsSZUVoUpRRcOjI_zrjKJeIemRQIFXhu8BR8TYYjjhM0i3lCEQSWOsqVTh_DqGkb_RQIy3MpclS3DkUxLijjhVFJrKmixogAov3XrKRnO7dNNxbVwNPsDKByeX1oAFUcwJtBZdVTfdx08viaiVxpFFGJsCAP4GRvB5V3C101GEEAL4ej-D_bRRre6HbbVbRARIgxcQBPekO7ujLFsQCjv2c3XvkE7vSzRDYN7jmMNuutfgG35e9N3a3HcMBmX5y8tHLOnCxQFqfx2P8-uPU5snL29fIvQyEgDw
linkProvider	ProQuest
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VggQS4tHyCIXWB-CAFJGnkxwQWlGqVl1WqCqot9SObRGxmyx5gHLn7_AfGTuPqgd664Fr4nEk-_PMODPzDcBLLwlYEHHXdoWv7CCS0uZ-4tsR9_0wFiIQITPNJqLFIj47Sz5vwJ-xFkanVY460ShqUWb6H_lbD_12RKPnvl__sHXTKB1cHTto9Kg4lt0vvLHV7472cXtfed7Bx9MPh_bQVMDO_JA2NuduoITkcZJxlhlCORYxEWZoezMvRnPFQoVD8FOKoS_BaeAyj6IjkkgnFNLHeW_ATVTjrs4gi06-Topf85iYYiaf2tRzojGI6hjOUl9z8OrrO9XZYJfM4N01q3FHVN9K49--rrF5B_f_s9V6APcG55rM-tPwEDZksQXbs4I15aojr4lJdzVxhC2w9nPZ4LOBGHVJFmNfgm34PW_XeUG-y6qQS6J0Ug3JTK2qUbBkVYpc5bImSmrJVd6zWTWMoFRfWdqRlSwIq4kY8o2kILwj1cliRvDMSqKWbVn1XFpaCleuJd86XT83VMY-gi_XslaPYbMoC_kUSBSGGQ9RXKtLETFOIxYr4bmSCqoUt8AZ0ZNmA5e7bimyTCcWagO41GQtIuBS14I3k8i6JzK5avDuJUheSMROgk5PaMHOiLt0UHp1OoHOgr3pLWorHYJihSzbOqUx-rt447fgSQ_si5kpWjq82z67cuY9uH14-mmezo8Wxztwp_8fphP-nsNmU7XyBdzKfjZ5Xe2ao0ng_LrR_RcxdHUX
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Lb9QwEB6VglAlxKMPCIXWB-CAFDVPJzkgtOqyomq1qhBIvQU7tkXEbrLkAcqdP8W_Y-wku-qB3nrgmmQcyfk8M46_-QbglZcELIi4a7vCV3YQSWlzP_HtiPt-GAsRiJCZZhPRfB5fXSWXW_BnrIXRtMrRJxpHLcpM_yM_8TBvRzR67okaWBGX09n71Q9bN5DSB61jN40eIeey-4W7t_rd2RQ_9WvPm334fPrRHhoM2Jkf0sbm3A2UkDxOMs4yIy7HIibCDONw5sUYulio8BF8rWKYV3AauMyjmJQk0gmF9HHcO3A38hHEukj9dMMu0ZomprDJpzb1nGg8UHWMfqmv9Xj1Vp5qZti1kPhgxWr8Oqpvq_HvvNfEv9mj_3jmHsPDIekmk36VPIEtWezC3qRgTbnsyBtiaLDmfGEXrGkuG7w2CKYuyHzsV7AHvy_aVV6Q77Iq5IIoTbYhmalhNY6XLEuRq1zWREltucx7lauGEbTqK047spQFYTURAw9JCsI7Un2aTwiuZUnUoi2rXmNLW-HMteRbp-vqhorZffhyK3N1ANtFWchnQKIwzHiI5tqNiohxGrFYCc-VVFCluAXOiKQ0GzTedauRRbpWpzbgSw2bEcGXuha8XZuseoGTmx4-ugbPjUXsJJgMhRYcjhhMB2dYp2sAWnC8voteTB9NsUKWbZ3SGPNgL0gseNqDfDMyxQiIe97nN458DPcR1OnF2fz8EHb632SaB_gCtpuqlS_hXvazyevqyKxSAl9vG9x_AdXmfXI
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Lupin+kernel+fiber+consumption+modifies+fecal+microbiota+in+healthy+men+as+determined+by+rRNA+gene+fluorescent+in+situ+hybridization&rft.jtitle=European+journal+of+nutrition&rft.au=Smith%2C+Stuart+C.&rft.au=Choy%2C+Rachel&rft.au=Johnson%2C+Stuart+K.&rft.au=Hall%2C+Ramon+S.&rft.date=2006-09-01&rft.issn=1436-6207&rft.eissn=1436-6215&rft.volume=45&rft.issue=6&rft.spage=335&rft.epage=341&rft_id=info:doi/10.1007%2Fs00394-006-0603-1&rft.externalDBID=n%2Fa&rft.externalDocID=10_1007_s00394_006_0603_1
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1436-6207&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1436-6207&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1436-6207&client=summon