The global burden of metabolic disease: Data from 2000 to 2019

Global estimates of prevalence, deaths, and disability-adjusted life years (DALYs) from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 were examined for metabolic diseases (type 2 diabetes mellitus [T2DM], hypertension, and non-alcoholic fatty liver disease [NAFLD]). For metabo...

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Vydáno v:	Cell metabolism Ročník 35; číslo 3; s. 414
Hlavní autoři:	Chew, Nicholas W S, Ng, Cheng Han, Tan, Darren Jun Hao, Kong, Gwyneth, Lin, Chaoxing, Chin, Yip Han, Lim, Wen Hui, Huang, Daniel Q, Quek, Jingxuan, Fu, Clarissa Elysia, Xiao, Jieling, Syn, Nicholas, Foo, Roger, Khoo, Chin Meng, Wang, Jiong-Wei, Dimitriadis, Georgios K, Young, Dan Yock, Siddiqui, Mohammad Shadab, Lam, Carolyn S P, Wang, Yibin, Figtree, Gemma A, Chan, Mark Y, Cummings, David E, Noureddin, Mazen, Wong, Vincent Wai-Sun, Ma, Ronald Ching Wan, Mantzoros, Christos S, Sanyal, Arun, Muthiah, Mark Dhinesh
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 07.03.2023
Témata:	Diabetes Mellitus, Type 2 - epidemiology Global Burden of Disease Humans Hypertension Metabolic Diseases - epidemiology Non-alcoholic Fatty Liver Disease Obesity - epidemiology Quality-Adjusted Life Years Risk Factors non-alcoholic fatty liver disease disparity disability-adjusted life years global burden of disease mortality diabetes mellitus metabolic disease hypertension global burden obesity
ISSN:	1932-7420, 1932-7420
On-line přístup:	Zjistit podrobnosti o přístupu
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Popis
Shrnutí:	Global estimates of prevalence, deaths, and disability-adjusted life years (DALYs) from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 were examined for metabolic diseases (type 2 diabetes mellitus [T2DM], hypertension, and non-alcoholic fatty liver disease [NAFLD]). For metabolic risk factors (hyperlipidemia and obesity), estimates were limited to mortality and DALYs. From 2000 to 2019, prevalence rates increased for all metabolic diseases, with the greatest increase in high socio-demographic index (SDI) countries. Mortality rates decreased over time in hyperlipidemia, hypertension, and NAFLD, but not in T2DM and obesity. The highest mortality was found in the World Health Organization Eastern Mediterranean region, and low to low-middle SDI countries. The global prevalence of metabolic diseases has risen over the past two decades regardless of SDI. Urgent attention is needed to address the unchanging mortality rates attributed to metabolic disease and the entrenched sex-regional-socioeconomic disparities in mortality.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1932-7420 1932-7420
DOI:	10.1016/j.cmet.2023.02.003