Exploring the bioactivity potential of indigenous Ganoderma species from Northern Serbia: insights into antioxidant and anti-acetylcholinesterase properties
This study explores the bioactivity potential of four indigenous species from northern Serbia ( , , , and ), comparing antioxidant and anti-acetylcholinesterase (anti-AChE) properties. The mycochemical profile, including ethanol (EtOH), water (H O), and chloroform (CHCl ) extracts, was analysed, rev...
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| Published in: | Natural product research pp. 1 - 12 |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
15.10.2024
|
| Subjects: | |
| ISSN: | 1478-6419, 1478-6427, 1478-6427 |
| Online Access: | Get full text |
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| Summary: | This study explores the bioactivity potential of four indigenous
species from northern Serbia (
,
,
, and
), comparing antioxidant and anti-acetylcholinesterase (anti-AChE) properties. The mycochemical profile, including ethanol (EtOH), water (H
O), and chloroform (CHCl
) extracts, was analysed, revealing significant phenolic compounds, such as 2,5-dihydroxybenzoic acid. Highest total phenolic content (TP) was in EtOH extracts (205 - 380 mg GAE/g d.w.), and total carbohydrate content peaked in
CHCl
extracts (1895 ± 0.29 mg GluE/g d.w., 439 ± 0.42 mg FruE/g d.w.). DPPH and FRAP activities were prominent in
H
O extracts, while CHCl
extracts excelled in the NO assay, and EtOH extracts were superior in the ABTS assay. The most effective AChE inhibitors were polar extracts from
. These findings emphasise the potential therapeutic use of
species, particularly
in combating oxidative stress and acetylcholine deficiencies. |
|---|---|
| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 1478-6419 1478-6427 1478-6427 |
| DOI: | 10.1080/14786419.2024.2415437 |