Development of the nephrotic syndrome during treatment of Crohn's disease with adalimumab

We report a patient with Crohn's disease who presented with renal insufficiency and the nephrotic syndrome after initiating therapy with adalimumab. Renal biopsy showed stages 2 to 3 membranous glomerulonephritis, and immunostaining showed glomerular deposition of immunoglobulin G and C3. The p...

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Veröffentlicht in:	Journal of clinical gastroenterology Jg. 45; H. 3; S. e30
Hauptverfasser:	Gupta, Alok, Pendyala, Prashant, Arora, Pradeep, Sitrin, Michael D
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.03.2011
Schlagworte:	Adalimumab Anti-Inflammatory Agents - adverse effects Anti-Inflammatory Agents - therapeutic use Antibodies, Monoclonal - adverse effects Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized Crohn Disease - complications Crohn Disease - drug therapy Humans Male Middle Aged Nephrotic Syndrome - chemically induced Nephrotic Syndrome - physiopathology
ISSN:	1539-2031, 1539-2031
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