Enoxaparin improves COVID-19 by reducing Neutrophils Extracellular Traps (NETs) production

COVID-19 causes consequences such as imbalance of the immune system and thrombotic events. During the infection process, NETs in excess induce a pro-inflammatory response and disseminated intravascular coagulation. We evaluated the role of enoxaparin as a potential inhibitor of NETs. K18-hACE2 anima...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Jg. 257; S. 109836
Hauptverfasser:	Córneo, Emily S., Veras, Flavio Protasio, Gomes, Giovanni F., Schneider, Ayda H., Manuella, Bruna, Almeida, Cicero J.L.R., Silva, Camila M., Martins, Ronaldo B., Batah, Sabrina S., Simon, Carla S., Prestes, Gabriele da S., Alves-Filho, José Carlos, Arruda, Eurico, Louzada-Junior, Paulo, de Oliveira, Renê D.R., Fabro, Alexandre T., Cunha, Thiago M., Cunha, Fernando Queiroz, Dal-Pizzol, Felipe
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Inc 01.12.2023
Schlagworte:	Animals COVID-19 Enoxaparin Enoxaparin - pharmacology Extracellular Traps Humans Inflammatory markers Lung injury NETs Neutrophils SARS-CoV-2 PBS Enoxaparin Inflammatory markers PFA MPO H3Cit COVID-19 SOFA SARS-CoV-2 NETs Enox NE Lung injury PAD-4
ISSN:	1521-6616, 1521-7035, 1521-7035
Online-Zugang:	Volltext
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