Legacy Data Confound Genomics Studies

Recent reports have identified differences in the mutational spectra across human populations. Although some of these reports have been replicated in other cohorts, most have been reported only in the 1000 Genomes Project (1kGP) data. While investigating an intriguing putative population stratificat...

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Veröffentlicht in:	Molecular biology and evolution Jg. 37; H. 1; S. 2 - 10
Hauptverfasser:	Anderson-Trocmé, Luke, Farouni, Rick, Bourgey, Mathieu, Kamatani, Yoichiro, Higasa, Koichiro, Seo, Jeong-Sun, Kim, Changhoon, Matsuda, Fumihiko, Gravel, Simon
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Oxford University Press 01.01.2020
Schlagworte:	Consortia Genetics Genome-Wide Association Study Genomes Genomics Human Genome Project Human populations Humans Japan Mutation Stratification Japan batch effect population genetics statistical genetics imputation reference cohorts mutational signature
ISSN:	0737-4038, 1537-1719, 1537-1719
Online-Zugang:	Volltext
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