Role of PI3K/Akt/mTOR pathway in mediating endocrine resistance: concept to clinic

The majority of breast cancers express the estrogen receptor (ER) and for this group of patients, endocrine therapy is the cornerstone of systemic treatment. However, drug resistance is common and a focus for breast cancer preclinical and clinical research. Over the past 2 decades, the PI3K/Akt/mTOR...

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Vydané v:	Exploration of targeted anti-tumor therapy Ročník 3; číslo 2; s. 172 - 199
Hlavní autori:	Skolariki, Aglaia, D’Costa, Jamie, Little, Martin, Lord, Simon
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Open Exploration 2022 Open Exploration Publishing Inc
Predmet:	breast cancer endocrine therapy pi3k/akt/mtor pathway Review
ISSN:	2692-3114, 2692-3114
On-line prístup:	Získať plný text
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