Role of PI3K/Akt/mTOR pathway in mediating endocrine resistance: concept to clinic

The majority of breast cancers express the estrogen receptor (ER) and for this group of patients, endocrine therapy is the cornerstone of systemic treatment. However, drug resistance is common and a focus for breast cancer preclinical and clinical research. Over the past 2 decades, the PI3K/Akt/mTOR...

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Bibliographic Details

Published in:	Exploration of targeted anti-tumor therapy Vol. 3; no. 2; pp. 172 - 199
Main Authors:	Skolariki, Aglaia, D’Costa, Jamie, Little, Martin, Lord, Simon
Format:	Journal Article
Language:	English
Published:	Open Exploration 2022 Open Exploration Publishing Inc
Subjects:	breast cancer endocrine therapy pi3k/akt/mtor pathway Review
ISSN:	2692-3114, 2692-3114
Online Access:	Get full text
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