Clinical and cost‐effectiveness of eye movement desensitization and reprocessing for treatment and prevention of post‐traumatic stress disorder in adults: A systematic review and meta‐analysis

The objective was to provide up‐to‐date clinical and cost‐effectiveness evidence investigating eye movement desensitization and reprocessing (EMDR) for treatment or prevention of adult post‐traumatic stress disorder (PTSD). We conducted a systematic review of randomized controlled trials (RCTs) and...

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Veröffentlicht in:The British journal of psychology Jg. 116; H. 4; S. 1128 - 1149
Hauptverfasser: Simpson, Emma, Carroll, Christopher, Sutton, Anthea, Forsyth, Jessica, Rayner, Annabel, Ren, Shijie, Franklin, Matthew, Wood, Emily
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England British Psychological Society 01.11.2025
Schlagworte:
Adult
Adults
Bayesian analysis
Bias
Clinical trials
Cognitive behavioral therapy
Cognitive Behavioral Therapy - economics
Cognitive-behavioral factors
Cost analysis
Cost-Benefit Analysis
Costs
Data
Desensitization
Effectiveness
Eye movement desensitization
eye movement desensitization and reprocessing
Eye Movement Desensitization Reprocessing - economics
Eye Movement Desensitization Reprocessing - methods
Eye movements
Humans
Medical research
Medical treatment
Meta-analysis
Post traumatic stress disorder
Prevention
Randomized Controlled Trials as Topic
Risk assessment
Stress Disorders, Post-Traumatic - economics
Stress Disorders, Post-Traumatic - prevention & control
Stress Disorders, Post-Traumatic - therapy
Symptoms
Systematic review
Trauma
Treatment outcomes
meta‐analysis
eye movement desensitization and reprocessing
systematic review
post‐traumatic stress disorder
ISSN:0007-1269, 2044-8295, 2044-8295
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Zusammenfassung:The objective was to provide up‐to‐date clinical and cost‐effectiveness evidence investigating eye movement desensitization and reprocessing (EMDR) for treatment or prevention of adult post‐traumatic stress disorder (PTSD). We conducted a systematic review of randomized controlled trials (RCTs) and cost‐effectiveness studies assessing PTSD symptoms in adults, published since the NICE 2018 guidelines. EMDR was compared with trauma‐focused‐cognitive behavioural therapy (TF‐CBT), waitlist or usual care. Six databases were searched in September 2023. Risk of bias was assessed. Data synthesis included Bayesian meta‐analyses of standardized mean differences if sufficient data were available from at least three RCTs. From 2038 records, 17 studies met the eligibility criteria. One modelling‐based study reported cost‐effectiveness, finding EMDR the most cost‐effective intervention compared to 10 others, including TF‐CBT. Sixteen RCTs (n = 1031) providing clinical PTSD outcome data were identified. Most studies had small sample sizes, and all but one was at high/moderate risk of bias. Additionally, 13 RCTs from NICE 2018 guidelines contributed to meta‐analyses. EMDR treatment was generally of shorter duration with a lower burden on patient time. Meta‐analyses found EMDR was statistically significantly better than waitlist/usual care. There was no significant difference in treatment effect between EMDR and TF‐CBT, both reported significantly improved PTSD symptoms.
Bibliographie:PROSPERO prospective register of systematic reviews CRD42023463360.
Registration
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0007-1269
2044-8295
2044-8295
DOI:10.1111/bjop.70005