l-carvone decreases breast cancer cells adhesion, migration, and invasion by suppressing FAK activation

Breast cancer is one of the most common types of cancer in the world and current therapeutic strategies present severe drawbacks. l-carvone (CRV), a monoterpene found in Mentha spicata (spearmint), has been reported to have potent anti-inflammatory activity. Here, we examined the role of CRV in brea...

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Bibliographic Details
Published in:	Chemico-biological interactions Vol. 378; p. 110480
Main Authors:	Lima, Lucas Trevisan França de, Ganzella, Fernando Augusto de Oliveira, Cardoso, Gabriela Casani, Pires, Verônica dos Santos, Chequin, Andressa, Santos, Giulia Luiza, Braun-Prado, Karin, Galindo, Claudia Martins, Braz Junior, Odair, Molento, Marcelo Beltrão, Acco, Alexandra, Adami, Eliana Rezende, Costa, Erico Tosoni, Cavichiolo Franco, Célia Regina, Klassen, Giseli, Ramos, Edneia Amancio de Souza
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 01.06.2023
Subjects:	Angiogenesis Animals Antiproliferative activity Carcinoma Cell Adhesion Cell Line, Tumor Cell Movement Ehrlich solid carcinoma Focal Adhesion Kinase 1 - metabolism Focal Adhesion Protein-Tyrosine Kinases - metabolism Integrin beta1 - metabolism Mice Monoterpene Neoplasm Invasiveness Vascular Endothelial Growth Factor A - metabolism Angiogenesis Monoterpene Antiproliferative activity Ehrlich solid carcinoma
ISSN:	0009-2797, 1872-7786, 1872-7786
Online Access:	Get full text
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