Characterization of signalling and regulation of common calcitonin receptor splice variants and polymorphisms

[Display omitted] The calcitonin receptor (CTR) is a class B G protein-coupled receptor that is a therapeutic target for the treatment of hypercalcaemia of malignancy, Paget’s disease and osteoporosis. In primates, the CTR is subject to alternative splicing, with a unique, primate-specific splice va...

Full description

Saved in:

Bibliographic Details
Published in:	Biochemical pharmacology Vol. 148; pp. 111 - 129
Main Authors:	Dal Maso, Emma, Just, Rasmus, Hick, Caroline, Christopoulos, Arthur, Sexton, Patrick M., Wootten, Denise, Furness, Sebastian G.B.
Format:	Journal Article
Language:	English
Published:	England Elsevier Inc 01.02.2018
Subjects:	Animals Calcitonin Calcitonin receptor Cercopithecus aethiops COS Cells G protein-coupled receptor Gene Expression Regulation HEK293 Cells Humans Polymorphism Polymorphism, Genetic Protein Isoforms Receptors, Calcitonin - genetics Receptors, Calcitonin - metabolism Signal Transduction - physiology Splice variant G protein-coupled receptor Splice variant Calcitonin receptor Calcitonin Polymorphism
ISSN:	0006-2952, 1873-2968, 1873-2968
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!