Effectiveness of cognitive behavioral therapy for perinatal maternal depression, anxiety and stress: A systematic review and meta-analysis of randomized controlled trials

Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This meta-analysis aims to comprehensively evaluate CBT efficacy for perinatal depression, anxiety and stress in the short term (from baseline to immediately...

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Veröffentlicht in:	Clinical psychology review Jg. 92; S. 102129
Hauptverfasser:	Li, Xinyuan, Laplante, David P., Paquin, Vincent, Lafortune, Sandra, Elgbeili, Guillaume, King, Suzanne
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Elsevier Ltd 01.03.2022
Schlagworte:	Anxiety Anxiety - therapy Anxiety Disorders - therapy Cognitive Behavioral Therapy Depression Depression - therapy Female Humans Meta-analysis Perinatal Randomized Controlled Trials as Topic Stress Perinatal Depression Anxiety Stress Cognitive behavioral therapy Meta-analysis
ISSN:	0272-7358, 1873-7811, 1873-7811
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Abstract	Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This meta-analysis aims to comprehensively evaluate CBT efficacy for perinatal depression, anxiety and stress in the short term (from baseline to immediately post-intervention) and in the long term (from baseline to the end of follow-up). Five databases were searched. We included 79 randomized controlled trials (RCTs) and quasi-RCTs assessing the efficacy of CBT during pregnancy and the first year postpartum. Primary outcome was the mean score change in depression, anxiety and stress. CBT-only and CBT plus other interventions were effective for perinatal maternal depression in the short term (SMD −0.69, 95% CI: −0.83, −0.55) and long term (SMD −0.59, 95% CI −0.75, −0.42). CBT-only had both short- and long-term efficacy for perinatal anxiety (short term: SMD −0.63, 95% CI −0.85, −0.42; long term: SMD −0.71, 95% CI −1.02, −0.39) and short-term efficacy for perinatal stress (SMD −0.96, 95% CI −1.40, −0.52). Overall, CBT was effective for perinatal maternal depression, anxiety and stress. CBT-only exhibited short-term efficacy for perinatal depression, anxiety and stress, and long-term efficacy for perinatal depression and anxiety. Subgroup analyses suggested that CBT-only was effective across a wide variety of modalities. •Overall, CBT is effective for perinatal maternal depression, anxiety and stress.•CBT-only is effective for perinatal depression in low-income women.•Partner-inclusive CBT-only is effective for depression, anxiety and stress.•CBT-only is effective in treating and preventing depression, anxiety and stress.•CBT plus other interventions showed short- and long-term efficacy for depression.
AbstractList	Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This meta-analysis aims to comprehensively evaluate CBT efficacy for perinatal depression, anxiety and stress in the short term (from baseline to immediately post-intervention) and in the long term (from baseline to the end of follow-up). Five databases were searched. We included 79 randomized controlled trials (RCTs) and quasi-RCTs assessing the efficacy of CBT during pregnancy and the first year postpartum. Primary outcome was the mean score change in depression, anxiety and stress. CBT-only and CBT plus other interventions were effective for perinatal maternal depression in the short term (SMD −0.69, 95% CI: −0.83, −0.55) and long term (SMD −0.59, 95% CI −0.75, −0.42). CBT-only had both short- and long-term efficacy for perinatal anxiety (short term: SMD −0.63, 95% CI −0.85, −0.42; long term: SMD −0.71, 95% CI −1.02, −0.39) and short-term efficacy for perinatal stress (SMD −0.96, 95% CI −1.40, −0.52). Overall, CBT was effective for perinatal maternal depression, anxiety and stress. CBT-only exhibited short-term efficacy for perinatal depression, anxiety and stress, and long-term efficacy for perinatal depression and anxiety. Subgroup analyses suggested that CBT-only was effective across a wide variety of modalities. •Overall, CBT is effective for perinatal maternal depression, anxiety and stress.•CBT-only is effective for perinatal depression in low-income women.•Partner-inclusive CBT-only is effective for depression, anxiety and stress.•CBT-only is effective in treating and preventing depression, anxiety and stress.•CBT plus other interventions showed short- and long-term efficacy for depression. Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This meta-analysis aims to comprehensively evaluate CBT efficacy for perinatal depression, anxiety and stress in the short term (from baseline to immediately post-intervention) and in the long term (from baseline to the end of follow-up). Five databases were searched. We included 79 randomized controlled trials (RCTs) and quasi-RCTs assessing the efficacy of CBT during pregnancy and the first year postpartum. Primary outcome was the mean score change in depression, anxiety and stress. CBT-only and CBT plus other interventions were effective for perinatal maternal depression in the short term (SMD -0.69, 95% CI: -0.83, -0.55) and long term (SMD -0.59, 95% CI -0.75, -0.42). CBT-only had both short- and long-term efficacy for perinatal anxiety (short term: SMD -0.63, 95% CI -0.85, -0.42; long term: SMD -0.71, 95% CI -1.02, -0.39) and short-term efficacy for perinatal stress (SMD -0.96, 95% CI -1.40, -0.52). Overall, CBT was effective for perinatal maternal depression, anxiety and stress. CBT-only exhibited short-term efficacy for perinatal depression, anxiety and stress, and long-term efficacy for perinatal depression and anxiety. Subgroup analyses suggested that CBT-only was effective across a wide variety of modalities.Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This meta-analysis aims to comprehensively evaluate CBT efficacy for perinatal depression, anxiety and stress in the short term (from baseline to immediately post-intervention) and in the long term (from baseline to the end of follow-up). Five databases were searched. We included 79 randomized controlled trials (RCTs) and quasi-RCTs assessing the efficacy of CBT during pregnancy and the first year postpartum. Primary outcome was the mean score change in depression, anxiety and stress. CBT-only and CBT plus other interventions were effective for perinatal maternal depression in the short term (SMD -0.69, 95% CI: -0.83, -0.55) and long term (SMD -0.59, 95% CI -0.75, -0.42). CBT-only had both short- and long-term efficacy for perinatal anxiety (short term: SMD -0.63, 95% CI -0.85, -0.42; long term: SMD -0.71, 95% CI -1.02, -0.39) and short-term efficacy for perinatal stress (SMD -0.96, 95% CI -1.40, -0.52). Overall, CBT was effective for perinatal maternal depression, anxiety and stress. CBT-only exhibited short-term efficacy for perinatal depression, anxiety and stress, and long-term efficacy for perinatal depression and anxiety. Subgroup analyses suggested that CBT-only was effective across a wide variety of modalities. Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This meta-analysis aims to comprehensively evaluate CBT efficacy for perinatal depression, anxiety and stress in the short term (from baseline to immediately post-intervention) and in the long term (from baseline to the end of follow-up). Five databases were searched. We included 79 randomized controlled trials (RCTs) and quasi-RCTs assessing the efficacy of CBT during pregnancy and the first year postpartum. Primary outcome was the mean score change in depression, anxiety and stress. CBT-only and CBT plus other interventions were effective for perinatal maternal depression in the short term (SMD -0.69, 95% CI: -0.83, -0.55) and long term (SMD -0.59, 95% CI -0.75, -0.42). CBT-only had both short- and long-term efficacy for perinatal anxiety (short term: SMD -0.63, 95% CI -0.85, -0.42; long term: SMD -0.71, 95% CI -1.02, -0.39) and short-term efficacy for perinatal stress (SMD -0.96, 95% CI -1.40, -0.52). Overall, CBT was effective for perinatal maternal depression, anxiety and stress. CBT-only exhibited short-term efficacy for perinatal depression, anxiety and stress, and long-term efficacy for perinatal depression and anxiety. Subgroup analyses suggested that CBT-only was effective across a wide variety of modalities.
ArticleNumber	102129
Author	Li, Xinyuan Paquin, Vincent King, Suzanne Laplante, David P. Elgbeili, Guillaume Lafortune, Sandra
Author_xml	– sequence: 1 givenname: Xinyuan surname: Li fullname: Li, Xinyuan organization: Integrated Program in Neuroscience, McGill University, Montreal, Canada – sequence: 2 givenname: David P. surname: Laplante fullname: Laplante, David P. organization: Centre for Child Development and Mental Health, Lady Davis Institute-Jewish General Hospital, Montreal, Canada – sequence: 3 givenname: Vincent surname: Paquin fullname: Paquin, Vincent organization: Department of Psychiatry, McGill University, Montreal, Canada – sequence: 4 givenname: Sandra surname: Lafortune fullname: Lafortune, Sandra organization: Department of Psychology, Université de Montréal, Montreal, Canada – sequence: 5 givenname: Guillaume surname: Elgbeili fullname: Elgbeili, Guillaume organization: Douglas Mental Health University Institute, Montreal, Canada – sequence: 6 givenname: Suzanne surname: King fullname: King, Suzanne email: suzanne.king@mcgill.ca organization: Department of Psychiatry, McGill University, Montreal, Canada
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/35123346$$D View this record in MEDLINE/PubMed
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Keywords	Perinatal Depression Anxiety Stress Cognitive behavioral therapy Meta-analysis
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Australian and New Zealand Journal of Psychiatry doi: 10.3109/00048679609065055
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Snippet	Cognitive behavioral therapy (CBT) has been widely studied in prenatal or postnatal depression, with much less research on anxiety and stress. This...
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SubjectTerms	Anxiety Anxiety - therapy Anxiety Disorders - therapy Cognitive Behavioral Therapy Depression Depression - therapy Female Humans Meta-analysis Perinatal Randomized Controlled Trials as Topic Stress
Title	Effectiveness of cognitive behavioral therapy for perinatal maternal depression, anxiety and stress: A systematic review and meta-analysis of randomized controlled trials
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