Angiotensin-converting enzyme 2 is subject to post-transcriptional regulation by miR-421

ACE2 (angiotensin converting enzyme 2) plays a critical role in the local tissue RAS (renin-angiotensin system) by hydrolysing the potent hypertensive and mitogenic peptide AngII (angiotensin II). Changes in the levels of ACE2 have been observed in a number of pathologies, including cardiovascular d...

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Vydané v:	Clinical science (1979) Ročník 127; číslo 4; s. 243
Hlavní autori:	Lambert, Daniel W, Lambert, Louise A, Clarke, Nicola E, Hooper, Nigel M, Porter, Karen E, Turner, Anthony J
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.08.2014
Predmet:	Angiotensin II - genetics Angiotensin II - metabolism Angiotensin-Converting Enzyme 2 Cardiovascular Diseases - genetics Cardiovascular Diseases - metabolism Down-Regulation - genetics Gene Expression Regulation - genetics Humans MicroRNAs - genetics MicroRNAs - metabolism Peptidyl-Dipeptidase A - metabolism Renin-Angiotensin System - genetics Transcription, Genetic
ISSN:	1470-8736, 1470-8736
On-line prístup:	Zistit podrobnosti o prístupe
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