Genetic Determined Iron Starvation Signature in Friedreich's Ataxia

Background Early studies in cellular models suggested an iron accumulation in Friedreich's ataxia (FA), yet findings from patients are lacking. Objectives The objective is to characterize systemic iron metabolism, body iron storages, and intracellular iron regulation in FA patients. Methods In...

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Vydané v:	Movement disorders Ročník 39; číslo 7; s. 1088 - 1098
Hlavní autori:	Grander, Manuel, Haschka, David, Indelicato, Elisabetta, Kremser, Christian, Amprosi, Matthias, Nachbauer, Wolfgang, Henninger, Benjamin, Stefani, Ambra, Högl, Birgit, Fischer, Christine, Seifert, Markus, Kiechl, Stefan, Weiss, Günter, Boesch, Sylvia
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Hoboken, USA John Wiley & Sons, Inc 01.07.2024 Wiley Subscription Services, Inc
Predmet:	Ataxia Divalent metal transporter-1 Down-regulation Erythropoiesis Ferritin Friedreich's ataxia Hemoglobin Hepatocytes Hepcidin Intracellular Iron Iron deficiency Leukocytes (mononuclear) Liver Magnetic resonance imaging Movement disorders MRI relaxometry mRNA Peripheral blood mononuclear cells Regulatory proteins Spleen Transferrins Friedreich's ataxia iron hepcidin MRI relaxometry liver
ISSN:	0885-3185, 1531-8257, 1531-8257
On-line prístup:	Získať plný text
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