Prenatally detected umbilical cord tumor as a sign of diffuse neonatal hemangiomatosis
We report a case of a prenatally detected hemangioma of the umbilical cord as an early sign of diffuse neonatal hemangiomatosis (DNH). The newborn was diagnosed with multiple hemangiomas in the liver, intestines, skin, and brain. Prenatal ultrasound findings, neonatal appearance of the hemangiomas,...
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| Published in: | Journal of clinical ultrasound Vol. 47; no. 6; pp. 366 - 368 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
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Hoboken, USA
John Wiley & Sons, Inc
01.07.2019
Wiley Subscription Services, Inc |
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| ISSN: | 0091-2751, 1097-0096, 1097-0096 |
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| Abstract | We report a case of a prenatally detected hemangioma of the umbilical cord as an early sign of diffuse neonatal hemangiomatosis (DNH). The newborn was diagnosed with multiple hemangiomas in the liver, intestines, skin, and brain. Prenatal ultrasound findings, neonatal appearance of the hemangiomas, and the associated complications are illustrated. Interdisciplinary investigations as well as operative and systemic treatment approaches proved to be challenging. This case illustrates how prenatal ultrasound with color Doppler facilitates the early diagnosis of DNH and can help through the early referral to specialized centers for appropriate treatment. |
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| AbstractList | We report a case of a prenatally detected hemangioma of the umbilical cord as an early sign of diffuse neonatal hemangiomatosis (DNH). The newborn was diagnosed with multiple hemangiomas in the liver, intestines, skin, and brain. Prenatal ultrasound findings, neonatal appearance of the hemangiomas, and the associated complications are illustrated. Interdisciplinary investigations as well as operative and systemic treatment approaches proved to be challenging. This case illustrates how prenatal ultrasound with color Doppler facilitates the early diagnosis of DNH and can help through the early referral to specialized centers for appropriate treatment. We report a case of a prenatally detected hemangioma of the umbilical cord as an early sign of diffuse neonatal hemangiomatosis (DNH). The newborn was diagnosed with multiple hemangiomas in the liver, intestines, skin, and brain. Prenatal ultrasound findings, neonatal appearance of the hemangiomas, and the associated complications are illustrated. Interdisciplinary investigations as well as operative and systemic treatment approaches proved to be challenging. This case illustrates how prenatal ultrasound with color Doppler facilitates the early diagnosis of DNH and can help through the early referral to specialized centers for appropriate treatment.We report a case of a prenatally detected hemangioma of the umbilical cord as an early sign of diffuse neonatal hemangiomatosis (DNH). The newborn was diagnosed with multiple hemangiomas in the liver, intestines, skin, and brain. Prenatal ultrasound findings, neonatal appearance of the hemangiomas, and the associated complications are illustrated. Interdisciplinary investigations as well as operative and systemic treatment approaches proved to be challenging. This case illustrates how prenatal ultrasound with color Doppler facilitates the early diagnosis of DNH and can help through the early referral to specialized centers for appropriate treatment. |
| Author | Henrich, Wolfgang Seeger, Karl‐Heinz Schwickert, Alexander Rancourt, Rebecca C. |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30673136$$D View this record in MEDLINE/PubMed |
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| Keywords | umbilical cord hemangioma diffuse neonatal hemangiomatosis color Doppler ultrasonography |
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| References_xml | – volume: 88 start-page: 93 year: 1999 end-page: 97 article-title: Diffuse neonatal haemangiomatosis: new views on diagnostic criteria and prognosis publication-title: Acta Paediatr – volume: 99 start-page: 58 year: 2007 article-title: Umbilical cord hemangioma associated with multiple cutaneous hemangiomas in a newborn publication-title: Int J Gynaecol Obstet – volume: 14 start-page: 68 year: 1999 end-page: 70 article-title: Pathophysiology and treatment of fetal anemia due to placental chorioangioma publication-title: Ultrasound Obstet Gynecol – volume: 25 start-page: 300 year: 2005 end-page: 303 article-title: The association of umbilical cord hemangioma with fetal vascular birthmarks publication-title: Prenat Diagn – volume: 46 start-page: 239 year: 2006 end-page: 242 article-title: Two infants with life‐threatening diffuse neonatal hemangiomatosis treated with cyclophosphamide publication-title: Pediatr Blood Cancer – volume: 44 start-page: 455 year: 2016 end-page: 458 article-title: The natural history of an umbilical cord hemangioma publication-title: J Clin Ultrasound – volume: 106 start-page: 83 year: 2003 end-page: 85 article-title: Benign multiple diffuse neonatal hemangiomatosis after a pregnancy complicated by polyhydramnios and a placental chorioangioma publication-title: Eur J Obstet Gynecol Reprod Biol – volume: 38 start-page: 246 year: 2009 end-page: 249 article-title: A rare case of placental chorioangioma associated with neonatal disseminated hemangiomatosis [in French] publication-title: J Gynecol Obstet Biol Reprod (Paris) – volume: 22 start-page: 520 year: 2008 end-page: 529 article-title: Haemangiomas and associated congenital malformations in a large population‐based sample of infants publication-title: Paediatr Perinat Epidemiol – ident: e_1_2_4_3_1 doi: 10.1002/pbc.20522 – ident: e_1_2_4_4_1 doi: 10.1111/j.1365-3016.2008.00957.x – ident: e_1_2_4_8_1 doi: 10.1016/j.ijgo.2007.02.016 – ident: e_1_2_4_6_1 doi: 10.1016/S0301-2115(02)00163-X – ident: e_1_2_4_9_1 doi: 10.1046/j.1469-0705.1999.14010068.x – ident: e_1_2_4_10_1 doi: 10.1002/jcu.22346 – ident: e_1_2_4_2_1 doi: 10.1111/j.1651-2227.1999.tb01276.x – ident: e_1_2_4_5_1 doi: 10.1016/j.jgyn.2008.09.013 – ident: e_1_2_4_7_1 doi: 10.1002/pd.1109 |
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| SubjectTerms | Adult Brain Case reports color Doppler Diagnosis, Differential diffuse neonatal hemangiomatosis Doppler effect Female Hemangioma Hemangioma - diagnostic imaging Hemangioma - embryology Hemangioma - pathology Humans Intestine Neonates Pregnancy Skin Ultrasonic imaging ultrasonography Ultrasonography, Doppler, Color Ultrasonography, Prenatal - methods Ultrasound Umbilical cord Umbilical Cord - diagnostic imaging Umbilical Cord - embryology Umbilical Cord - pathology umbilical cord hemangioma Vascular Neoplasms - diagnostic imaging Vascular Neoplasms - embryology Vascular Neoplasms - pathology |
| Title | Prenatally detected umbilical cord tumor as a sign of diffuse neonatal hemangiomatosis |
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