Pulsed electromagnetic field therapy in the treatment of pain and other symptoms in fibromyalgia: A randomized controlled study
Low‐energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with f...
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| Vydané v: | Bioelectromagnetics Ročník 39; číslo 5; s. 405 - 413 |
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| Hlavní autori: | , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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01.07.2018
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| ISSN: | 0197-8462, 1521-186X, 1521-186X |
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| Abstract | Low‐energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12‐week treatment period with an active Bio‐Electro‐Magnetic‐Energy‐Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order. Pain and stiffness were assessed on a visual analog scale (VAS, scale 0–100 mm), and functional status was assessed by the Fibromyalgia Impact Questionnaire (FIQ). Mean VAS pain scores before the active and sham treatment periods were 66 (SD 22) and 63 (SD 22), respectively. After treatment periods, mean VAS pain scores had decreased significantly in active treatment, −12, 95% CI [−18, −6], and in sham treatment, −11, 95% CI [−17, −5]. Similarly, the decrease in stiffness and FIQ index after both treatments was statistically significant. However, per‐protocol analysis showed no differences between active and sham treatments at any of the outcomes. This study demonstrated that low‐energy PEMF therapy was not efficient in reducing pain and stiffness or in improving functioning in women with fibromyalgia. Bioelectromagnetics. 39:405–413, 2018. © 2018 Wiley Periodicals, Inc. |
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| AbstractList | Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12-week treatment period with an active Bio-Electro-Magnetic-Energy-Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order. Pain and stiffness were assessed on a visual analog scale (VAS, scale 0-100 mm), and functional status was assessed by the Fibromyalgia Impact Questionnaire (FIQ). Mean VAS pain scores before the active and sham treatment periods were 66 (SD 22) and 63 (SD 22), respectively. After treatment periods, mean VAS pain scores had decreased significantly in active treatment, -12, 95% CI [-18, -6], and in sham treatment, -11, 95% CI [-17, -5]. Similarly, the decrease in stiffness and FIQ index after both treatments was statistically significant. However, per-protocol analysis showed no differences between active and sham treatments at any of the outcomes. This study demonstrated that low-energy PEMF therapy was not efficient in reducing pain and stiffness or in improving functioning in women with fibromyalgia. Bioelectromagnetics. 39:405-413, 2018. © 2018 Wiley Periodicals, Inc.Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12-week treatment period with an active Bio-Electro-Magnetic-Energy-Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order. Pain and stiffness were assessed on a visual analog scale (VAS, scale 0-100 mm), and functional status was assessed by the Fibromyalgia Impact Questionnaire (FIQ). Mean VAS pain scores before the active and sham treatment periods were 66 (SD 22) and 63 (SD 22), respectively. After treatment periods, mean VAS pain scores had decreased significantly in active treatment, -12, 95% CI [-18, -6], and in sham treatment, -11, 95% CI [-17, -5]. Similarly, the decrease in stiffness and FIQ index after both treatments was statistically significant. However, per-protocol analysis showed no differences between active and sham treatments at any of the outcomes. This study demonstrated that low-energy PEMF therapy was not efficient in reducing pain and stiffness or in improving functioning in women with fibromyalgia. Bioelectromagnetics. 39:405-413, 2018. © 2018 Wiley Periodicals, Inc. Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12-week treatment period with an active Bio-Electro-Magnetic-Energy-Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order. Pain and stiffness were assessed on a visual analog scale (VAS, scale 0-100 mm), and functional status was assessed by the Fibromyalgia Impact Questionnaire (FIQ). Mean VAS pain scores before the active and sham treatment periods were 66 (SD 22) and 63 (SD 22), respectively. After treatment periods, mean VAS pain scores had decreased significantly in active treatment, -12, 95% CI [-18, -6], and in sham treatment, -11, 95% CI [-17, -5]. Similarly, the decrease in stiffness and FIQ index after both treatments was statistically significant. However, per-protocol analysis showed no differences between active and sham treatments at any of the outcomes. This study demonstrated that low-energy PEMF therapy was not efficient in reducing pain and stiffness or in improving functioning in women with fibromyalgia. Bioelectromagnetics. 39:405-413, 2018. © 2018 Wiley Periodicals, Inc. Low‐energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12‐week treatment period with an active Bio‐Electro‐Magnetic‐Energy‐Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order. Pain and stiffness were assessed on a visual analog scale (VAS, scale 0–100 mm), and functional status was assessed by the Fibromyalgia Impact Questionnaire (FIQ). Mean VAS pain scores before the active and sham treatment periods were 66 (SD 22) and 63 (SD 22), respectively. After treatment periods, mean VAS pain scores had decreased significantly in active treatment, −12, 95% CI [−18, −6], and in sham treatment, −11, 95% CI [−17, −5]. Similarly, the decrease in stiffness and FIQ index after both treatments was statistically significant. However, per‐protocol analysis showed no differences between active and sham treatments at any of the outcomes. This study demonstrated that low‐energy PEMF therapy was not efficient in reducing pain and stiffness or in improving functioning in women with fibromyalgia. Bioelectromagnetics. 39:405–413, 2018. © 2018 Wiley Periodicals, Inc. |
| Author | Heikkinen, Pauli Multanen, Juhani Mustalampi, Sirpa Häkkinen, Arja Kautiainen, Hannu Ylinen, Jari |
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| Cites_doi | 10.1515/jcim-2013-0035 10.1186/1745-6215-10-27 10.1017/S0033291700009934 10.2340/16501977-0168 10.1097/PSY.0b013e3181a32da0 10.3109/15368378.2015.1077338 10.1016/j.sjpain.2011.10.004 10.1002/jor.1100080217 10.1002/bem.21983 10.1002/art.10225 10.1136/annrheumdis-2016-209724 10.1097/BOR.0b013e328333b9cc 10.1016/j.pnpbp.2010.07.030 10.1002/acr.21896 10.1067/mem.2001.118012 10.4103/0028-3886.57820 10.1016/j.semarthrit.2006.12.009 10.1093/rheumatology/kev426 10.1136/bjsm.2009.059808 10.1155/2006/842162 10.1111/j.1600-079X.2010.00836.x 10.1155/2012/741746 10.4070/kcj.2011.41.10.596 10.1186/ar1459 10.1093/rheumatology/keh027 10.36076/ppj/2017/25 10.1007/s11916-015-0527-7 10.1155/2013/485272 10.4065/mcp.2011.0206 10.1097/AJP.0b013e3181a68a6c 10.1002/art.1780400905 10.3904/kjim.2015.30.4.531 10.1155/2007/626072 10.1089/107555301300004538 10.1016/j.yexmp.2006.09.008 10.1016/j.jspi.2007.05.005 10.1515/jcim-2013-0037 10.1682/JRRD.2015.04.0061 10.1016/j.neubiorev.2007.01.003 10.1007/s00296-012-2390-8 10.1016/j.jneuroim.2011.10.013 10.1016/S0304-3959(03)00139-8 10.1002/bem.20703 10.1186/ar4079 10.1016/j.pain.2013.07.043 10.1016/j.ejim.2007.10.006 |
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| References | 2015; 34 1991; 18 2012; 242 1997; 40 2009; 43 2013; 65 2015; 30 2007; 31 2012; 14 2016; 37 2007; 36 2010; 22 2009; 57 2009; 10 2013; 10 2002; 46 2017; 76 2013; 154 2004; 43 2017; 20 2009; 25 2015; 19 2013; 49 2012 1988; 18 2006; 11 2008; 19 2016; 53 2007 2011; 35 1991 2012; 33 2007; 12 2016; 55 2012; 3 2001; 7 2013; 33 2009; 71 2011; 50 2011; 86 2011; 41 2005; 7 2008; 138 2001; 38 2009; 6 2007; 83 2014 2013 2003; 104 2008; 40 1990; 8 e_1_2_7_3_1 e_1_2_7_7_1 e_1_2_7_19_1 e_1_2_7_17_1 e_1_2_7_15_1 e_1_2_7_41_1 Salazar AP (e_1_2_7_44_1) 2017; 20 e_1_2_7_43_1 e_1_2_7_11_1 e_1_2_7_45_1 e_1_2_7_47_1 e_1_2_7_26_1 e_1_2_7_49_1 e_1_2_7_28_1 Busch AJ (e_1_2_7_12_1) 2007 Burckhardt CS (e_1_2_7_10_1) 1991; 18 Altman DG (e_1_2_7_5_1) 1991 e_1_2_7_50_1 Cuatrecasas G (e_1_2_7_18_1) 2009; 6 e_1_2_7_25_1 e_1_2_7_31_1 e_1_2_7_52_1 e_1_2_7_23_1 e_1_2_7_54_1 Busch AJ (e_1_2_7_13_1) 2013 e_1_2_7_21_1 e_1_2_7_35_1 e_1_2_7_37_1 e_1_2_7_39_1 e_1_2_7_6_1 e_1_2_7_4_1 e_1_2_7_8_1 e_1_2_7_16_1 e_1_2_7_40_1 e_1_2_7_2_1 e_1_2_7_42_1 Carbonario F (e_1_2_7_14_1) 2013; 49 e_1_2_7_46_1 e_1_2_7_48_1 e_1_2_7_27_1 e_1_2_7_29_1 Li S (e_1_2_7_33_1) 2013 e_1_2_7_51_1 e_1_2_7_30_1 e_1_2_7_53_1 Bohn W (e_1_2_7_9_1) 2013; 10 e_1_2_7_24_1 e_1_2_7_32_1 e_1_2_7_55_1 e_1_2_7_22_1 e_1_2_7_34_1 e_1_2_7_20_1 e_1_2_7_36_1 e_1_2_7_38_1 |
| References_xml | – volume: 57 start-page: 622 year: 2009 end-page: 626 article-title: Efficacy of pulsed electromagnetic field therapy in healing of pressure ulcers: a randomized control trial publication-title: Neurol India – volume: 36 start-page: 339 year: 2007 end-page: 356 article-title: Fibromyalgia and overlapping disorders: the unifying concept of central sensitivity syndromes publication-title: Semin Arthritis Rheum – volume: 8 start-page: 276 year: 1990 end-page: 282 article-title: Effect of low frequency pulsing electromagnetic fields on skin ulcers of venous origin in humans: a double‐blind study publication-title: J Orthop Res – volume: 37 start-page: 290 year: 2016 end-page: 297 article-title: Effects of pulsed electromagnetic fields on peripheral blood circulation in people with diabetes: a randomized controlled trial publication-title: Bioelectromagnetics – volume: 7 start-page: R209 year: 2005 end-page: R216 article-title: Microcirculation abnormalities in patients with fibromyalgia—measured by capillary microscopy and laser fluxmetry publication-title: Arthritis Res Ther – volume: 10 year: 2009 article-title: Design, analysis, and presentation of crossover trials publication-title: Trials – volume: 35 start-page: 730 year: 2011 end-page: 743 article-title: Beyond the serotonin hypothesis: mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders publication-title: Prog Neuropsychopharmacol Biol Psychiatry – volume: 31 start-page: 619 year: 2007 end-page: 642 article-title: Pain perception and electromagnetic fields publication-title: Neurosci Biobehav Rev – year: 2012 article-title: Dysfunctional neurotransmitter systems in fibromyalgia, their role in central stress circuitry and pharmacological actions on these systems publication-title: Pain Res Treat – volume: 14 start-page: R236 year: 2012 article-title: Noninvasive optical characterization of muscle blood flow, oxygenation, and metabolism in women with fibromyalgia publication-title: Arthritis Res Ther – year: 2014 – volume: 43 start-page: 550 year: 2009 end-page: 555 article-title: Evidence on the effects of exercise therapy in the treatment of chronic disease publication-title: Br J Sports Med – volume: 3 start-page: 15 year: 2012 end-page: 20 article-title: Validation of a finnish version of the fibromyalgia impact questionnaire (Finn‐FIQ) publication-title: Scand J Pain – volume: 19 start-page: 350 year: 2008 end-page: 355 article-title: Efficacy of Raloxifen in treatment of fibromyalgia in menopausal women publication-title: Eur J Intern Med – volume: 33 start-page: 95 year: 2012 end-page: 105 article-title: Therapeutic effects of whole‐body devices applying pulsed electromagnetic fields (PEMF): a systematic literature review publication-title: Bioelectromagnetics – volume: 7 start-page: 53 year: 2001 end-page: 64 article-title: Static magnetic fields for treatment of fibromyalgia: a randomized controlled trial publication-title: J Altern Complement Med – volume: 6 start-page: 529 year: 2009 end-page: 533 article-title: Fibromyalgic syndromes: could growth hormone therapy be beneficial publication-title: Pediatr Endocrinol Rev – volume: 34 start-page: 190 year: 2015 end-page: 196 article-title: XXIst century magnetotherapy publication-title: Electromagn Biol Med – volume: 18 start-page: 1007 year: 1988 end-page: 1019 article-title: Clinical applications of visual analogue scales: a critical review publication-title: Psychol Med – volume: 22 start-page: 59 year: 2010 end-page: 63 article-title: Rheumatic manifestations of sleep disorders publication-title: Curr Opin Rheumatol – volume: 19 start-page: 55‐015‐0527‐7 year: 2015 article-title: The role and importance of small fiber neuropathy in fibromyalgia pain publication-title: Curr Pain Headache Rep – volume: 86 start-page: 907 year: 2011 end-page: 911 article-title: The science of fibromyalgia publication-title: Mayo Clin Proc – volume: 33 start-page: 649 year: 2013 end-page: 655 article-title: Efficacy of supervised exercise combined with transcutaneous electrical nerve stimulation in women with fibromyalgia: a prospective controlled study publication-title: Rheumatol Int – volume: 11 start-page: 85 year: 2006 end-page: 90 article-title: Exposure to a specific pulsed low‐frequency magnetic field: a double‐blind placebo‐controlled study of effects on pain ratings in rheumatoid arthritis and fibromyalgia patients publication-title: Pain Res Manag – volume: 138 start-page: 278 year: 2008 end-page: 285 article-title: Optimal and efficient crossover designs for comparing test treatments to a control treatment under various models publication-title: J Stat Plan Inference – volume: 104 start-page: 665 year: 2003 end-page: 672 article-title: The effect of combined therapy (ultrasound and interferential current) on pain and sleep in fibromyalgia publication-title: Pain – volume: 41 start-page: 596 year: 2011 end-page: 602 article-title: Arterial stiffness in female patients with fibromyalgia and its relationship to chronic emotional and physical stress publication-title: Korean Circ J – volume: 50 start-page: 267 year: 2011 end-page: 271 article-title: Adjuvant use of melatonin for treatment of fibromyalgia publication-title: J Pineal Res – volume: 38 start-page: 639 year: 2001 end-page: 643 article-title: Clinically significant changes in pain along the visual analog scale publication-title: Ann Emerg Med – volume: 25 start-page: 722 year: 2009 end-page: 728 article-title: Low‐frequency pulsed electromagnetic field therapy in fibromyalgia: a randomized, double‐blind, sham‐controlled clinical study publication-title: Clin J Pain – start-page: 447 year: 1991 end-page: 448 – volume: 43 start-page: 225 year: 2004 end-page: 228 article-title: Changes in knee extension and flexion force, EMG and functional capacity during strength training in older females with fibromyalgia and healthy controls publication-title: Rheumatology (Oxford) – volume: 53 start-page: 1023 year: 2016 end-page: 1034 article-title: Efficacy of extremely low‐frequency magnetic field in fibromyalgia pain: a pilot study publication-title: J Rehabil Res Dev – volume: 65 start-page: 786 year: 2013 end-page: 792 article-title: Prevalence of fibromyalgia: a population‐based study in olmsted county, minnesota, utilizing the Rochester epidemiology project publication-title: Arthritis Care Res (Hoboken) – volume: 40 start-page: 248 year: 2008 end-page: 252 article-title: Eight months of physical training in warm water improves physical and mental health in women with fibromyalgia: a randomized controlled trial publication-title: J Rehabil Med – start-page: CD003786 year: 2007 article-title: Exercise for treating fibromyalgia syndrome publication-title: Cochrane Database Syst Rev – volume: 30 start-page: 531 year: 2015 end-page: 537 article-title: Quantitative analysis of nailfold capillary morphology in patients with fibromyalgia publication-title: Korean J Intern Med – volume: 18 start-page: 728 year: 1991 end-page: 733 article-title: The fibromyalgia impact questionnaire: development and validation publication-title: J Rheumatol – volume: 49 start-page: 197 year: 2013 end-page: 204 article-title: Effectiveness of high‐frequency transcutaneous electrical nerve stimulation at tender points as adjuvant therapy for patients with fibromyalgia publication-title: Eur J Phys Rehabil Med – volume: 76 start-page: 318 year: 2017 end-page: 328 article-title: EULAR revised recommendations for the management of fibromyalgia publication-title: Ann Rheum Dis – volume: 71 start-page: 566 year: 2009 end-page: 573 article-title: Decreased gray matter volumes in the cingulo‐frontal cortex and the amygdala in patients with fibromyalgia publication-title: Psychosom Med – volume: 12 start-page: 249 year: 2007 end-page: 258 article-title: A randomized, double‐blind, placebo‐controlled clinical trial using a low‐frequency magnetic field in the treatment of musculoskeletal chronic pain publication-title: Pain Res Manag – volume: 46 start-page: 1333 year: 2002 end-page: 1343 article-title: Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia publication-title: Arthritis Rheum – volume: 10 start-page: S5‐12 year: 2013 article-title: The effects of the “physical BEMER® vascular therapy”, a method for the physical stimulation of the vasomotion of precapillary microvessels in case of impaired microcirculation, on sleep, pain and quality of life of patients with different clinical pictures on the basis of three scientifically validated scales publication-title: J Complement Integr Med – start-page: CD003523 year: 2013 article-title: Electromagnetic fields for treating osteoarthritis publication-title: Cochrane Database Syst Rev – start-page: CD010884 year: 2013 article-title: Resistance exercise training for fibromyalgia publication-title: Cochrane Database Syst Rev – volume: 10 start-page: S39‐46 year: 2013 article-title: Effects of various physical treatment methods on arteriolar vasomotion and microhemodynamic functional characteristics in case of deficient regulation of organ blood flow. Results of a placebo‐controlled, double‐blind study publication-title: J Complement Integr Med – volume: 55 start-page: 755 year: 2016 end-page: 762 article-title: Pulsed electromagnetic fields in knee osteoarthritis: a double blind, placebo‐controlled, randomized clinical trial publication-title: Rheumatology (Oxford) – year: 2013 article-title: Treatment of fibromyalgia syndrome: recommendations of recent evidence‐based interdisciplinary guidelines with special emphasis on complementary and alternative therapies publication-title: Evid Based Complement Alternat Med – volume: 40 start-page: 1571 year: 1997 end-page: 1579 article-title: Health status and disease severity in fibromyalgia: results of a six‐center longitudinal study publication-title: Arthritis Rheum – volume: 154 start-page: 2554 year: 2013 end-page: 2562 article-title: Transcutaneous electrical nerve stimulation reduces pain, fatigue and hyperalgesia while restoring central inhibition in primary fibromyalgia publication-title: Pain – volume: 83 start-page: 84 year: 2007 end-page: 92 article-title: Mitochondrial dysfunction and molecular pathways of disease publication-title: Exp Mol Pathol – volume: 242 start-page: 33 year: 2012 end-page: 38 article-title: Evidence of central inflammation in fibromyalgia‐increased cerebrospinal fluid interleukin‐8 levels publication-title: J Neuroimmunol – volume: 20 start-page: 15 year: 2017 end-page: 25 article-title: Electric stimulation for pain relief in patients with fibromyalgia: a systematic review and meta‐analysis of randomized controlled trials publication-title: Pain Physician – ident: e_1_2_7_30_1 doi: 10.1515/jcim-2013-0035 – start-page: CD003523 year: 2013 ident: e_1_2_7_33_1 article-title: Electromagnetic fields for treating osteoarthritis publication-title: Cochrane Database Syst Rev – ident: e_1_2_7_37_1 doi: 10.1186/1745-6215-10-27 – start-page: CD003786 year: 2007 ident: e_1_2_7_12_1 article-title: Exercise for treating fibromyalgia syndrome publication-title: Cochrane Database Syst Rev – start-page: CD010884 year: 2013 ident: e_1_2_7_13_1 article-title: Resistance exercise training for fibromyalgia publication-title: Cochrane Database Syst Rev – ident: e_1_2_7_36_1 doi: 10.1017/S0033291700009934 – ident: e_1_2_7_50_1 doi: 10.2340/16501977-0168 – ident: e_1_2_7_11_1 doi: 10.1097/PSY.0b013e3181a32da0 – volume: 18 start-page: 728 year: 1991 ident: e_1_2_7_10_1 article-title: The fibromyalgia impact questionnaire: development and validation publication-title: J Rheumatol – ident: e_1_2_7_35_1 doi: 10.3109/15368378.2015.1077338 – ident: e_1_2_7_22_1 doi: 10.1016/j.sjpain.2011.10.004 – ident: e_1_2_7_28_1 doi: 10.1002/jor.1100080217 – ident: e_1_2_7_47_1 doi: 10.1002/bem.21983 – ident: e_1_2_7_24_1 doi: 10.1002/art.10225 – ident: e_1_2_7_34_1 doi: 10.1136/annrheumdis-2016-209724 – ident: e_1_2_7_38_1 doi: 10.1097/BOR.0b013e328333b9cc – ident: e_1_2_7_21_1 doi: 10.1016/j.pnpbp.2010.07.030 – ident: e_1_2_7_52_1 doi: 10.1002/acr.21896 – ident: e_1_2_7_8_1 doi: 10.1067/mem.2001.118012 – ident: e_1_2_7_25_1 doi: 10.4103/0028-3886.57820 – ident: e_1_2_7_55_1 doi: 10.1016/j.semarthrit.2006.12.009 – ident: e_1_2_7_6_1 doi: 10.1093/rheumatology/kev426 – ident: e_1_2_7_31_1 doi: 10.1136/bjsm.2009.059808 – ident: e_1_2_7_46_1 doi: 10.1155/2006/842162 – ident: e_1_2_7_27_1 doi: 10.1111/j.1600-079X.2010.00836.x – ident: e_1_2_7_7_1 doi: 10.1155/2012/741746 – ident: e_1_2_7_32_1 doi: 10.4070/kcj.2011.41.10.596 – ident: e_1_2_7_39_1 doi: 10.1186/ar1459 – ident: e_1_2_7_51_1 doi: 10.1093/rheumatology/keh027 – volume: 20 start-page: 15 year: 2017 ident: e_1_2_7_44_1 article-title: Electric stimulation for pain relief in patients with fibromyalgia: a systematic review and meta‐analysis of randomized controlled trials publication-title: Pain Physician doi: 10.36076/ppj/2017/25 – ident: e_1_2_7_15_1 doi: 10.1007/s11916-015-0527-7 – ident: e_1_2_7_2_1 doi: 10.1155/2013/485272 – ident: e_1_2_7_17_1 doi: 10.4065/mcp.2011.0206 – volume: 6 start-page: 529 year: 2009 ident: e_1_2_7_18_1 article-title: Fibromyalgic syndromes: could growth hormone therapy be beneficial publication-title: Pediatr Endocrinol Rev – ident: e_1_2_7_48_1 doi: 10.1097/AJP.0b013e3181a68a6c – ident: e_1_2_7_53_1 doi: 10.1002/art.1780400905 – ident: e_1_2_7_16_1 doi: 10.3904/kjim.2015.30.4.531 – ident: e_1_2_7_49_1 doi: 10.1155/2007/626072 – ident: e_1_2_7_3_1 doi: 10.1089/107555301300004538 – ident: e_1_2_7_42_1 doi: 10.1016/j.yexmp.2006.09.008 – ident: e_1_2_7_54_1 doi: 10.1016/j.jspi.2007.05.005 – volume: 49 start-page: 197 year: 2013 ident: e_1_2_7_14_1 article-title: Effectiveness of high‐frequency transcutaneous electrical nerve stimulation at tender points as adjuvant therapy for patients with fibromyalgia publication-title: Eur J Phys Rehabil Med – volume: 10 start-page: S5‐12 year: 2013 ident: e_1_2_7_9_1 article-title: The effects of the “physical BEMER® vascular therapy”, a method for the physical stimulation of the vasomotion of precapillary microvessels in case of impaired microcirculation, on sleep, pain and quality of life of patients with different clinical pictures on the basis of three scientifically validated scales publication-title: J Complement Integr Med doi: 10.1515/jcim-2013-0037 – ident: e_1_2_7_41_1 doi: 10.1682/JRRD.2015.04.0061 – ident: e_1_2_7_20_1 doi: 10.1016/j.neubiorev.2007.01.003 – ident: e_1_2_7_40_1 doi: 10.1007/s00296-012-2390-8 – start-page: 447 volume-title: Practical statistics for medical research year: 1991 ident: e_1_2_7_5_1 – ident: e_1_2_7_29_1 doi: 10.1016/j.jneuroim.2011.10.013 – ident: e_1_2_7_4_1 doi: 10.1016/S0304-3959(03)00139-8 – ident: e_1_2_7_26_1 doi: 10.1002/bem.20703 – ident: e_1_2_7_45_1 doi: 10.1186/ar4079 – ident: e_1_2_7_19_1 doi: 10.1016/j.pain.2013.07.043 – ident: e_1_2_7_23_1 – ident: e_1_2_7_43_1 doi: 10.1016/j.ejim.2007.10.006 |
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| SubjectTerms | Adult chronic pain Cross-Over Studies Double-Blind Method Electromagnetic fields Electromagnetism Energy Female Fibromyalgia Fibromyalgia - physiopathology Fibromyalgia - therapy Follow-Up Studies Humans Magnetic Field Therapy - methods magnetotherapy microcirculation Middle Aged Pain Pain - physiopathology Pain Management - methods Pain Measurement Patient Dropouts Patients pulsed electromagnetic field sham treatment Statistical analysis Stiffness Surveys and Questionnaires Therapy Treatment Outcome Young Adult |
| Title | Pulsed electromagnetic field therapy in the treatment of pain and other symptoms in fibromyalgia: A randomized controlled study |
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