Paediatric‐onset and adult‐onset Graves' disease share multiple genetic risk factors

Background Graves' disease (GD) is an autoimmune thyroid disease (AITD) with a peak incidence between 30 and 50 years of age. Although children and adolescents may also develop the disease, the genetic background of paediatric‐onset GD (POGD) remains largely unknown. Here, we looked for similar...

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Vydáno v:	Clinical endocrinology (Oxford) Ročník 90; číslo 2; s. 320 - 327
Hlavní autoři:	Kuś, Aleksander, Radziszewski, Mikołaj, Glina, Aleksandra, Szymański, Konrad, Jurecka‐Lubieniecka, Beata, Pawlak‐Adamska, Edyta, Kula, Dorota, Wawrusiewicz‐Kurylonek, Natalia, Kuś, Joanna, Miśkiewicz, Piotr, Płoski, Rafał, Bolanowski, Marek, Daroszewski, Jacek, Jarząb, Barbara, Bossowski, Artur, Bednarczuk, Tomasz
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Wiley Subscription Services, Inc 01.02.2019
Témata:	Adolescents Adult Age Age of Onset Alleles autoimmunity Case-Control Studies Child Children Drb1 protein Gene Frequency Gene polymorphism Genetic Predisposition to Disease genetics Graves Disease - genetics Graves' disease HCP5 Health risk assessment Histocompatibility antigen HLA Humans Risk Factors Single-nucleotide polymorphism Thyroid HCP5 genetics autoimmunity thyroid Graves' disease children single nucleotide polymorphism
ISSN:	0300-0664, 1365-2265, 1365-2265
On-line přístup:	Získat plný text
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