Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS

Oxidative stress (OS) induces inflammation, which in turn exacerbates OS and the expression of acute phase proteins (APPs). Regulatory T lymphocyte (Treg) therapy was assessed for suppression of OS and APP responses in longitudinal serum samples from subjects with amyotrophic lateral sclerosis (ALS)...

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Bibliographic Details
Published in:	Annals of neurology Vol. 92; no. 2; pp. 195 - 200
Main Authors:	Beers, David R., Thonhoff, Jason R., Faridar, Alireza, Thome, Aaron D., Zhao, Weihua, Wen, Shixiang, Appel, Stanley H.
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01.08.2022 Wiley Subscription Services, Inc
Subjects:	Acute phase proteins Acute-Phase Proteins - metabolism Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - metabolism Amyotrophic Lateral Sclerosis - therapy CD14 antigen Clinical Trials, Phase I as Topic Humans Inflammation Inflammation - metabolism Lipopolysaccharides Low density lipoprotein Lymphocytes Lymphocytes T Oxidative Stress Proteins Serum levels T-Lymphocytes, Regulatory - metabolism Therapy
ISSN:	0364-5134, 1531-8249, 1531-8249
Online Access:	Get full text
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