Study of IL4‐590C/T and IL6‐174G/C Gene Polymorphisms in Type 2 Diabetic Patients With Chronic Kidney Disease in North Indian Population

ABSTRACT To explore the associations between potential functional promoter polymorphisms in pro‐inflammatory and anti‐inflammatory (IL‐4(‐590C/T) and IL‐6(‐174G/C) cytokine genes, and kidney dysfunction in North Indian type 2 diabetic subjects with chronic kidney disease. A total of 150 subjects age...

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Bibliographic Details
Published in:	Journal of cellular biochemistry Vol. 118; no. 7; pp. 1803 - 1809
Main Authors:	Neelofar, Km, Ahmad, Jamal, Ahmad, Arif, Alam, Khursheed
Format:	Journal Article
Language:	English
Published:	United States Wiley Subscription Services, Inc 01.07.2017
Subjects:	Adult Aged Asian Continental Ancestry Group C gene CKD Creatinine Creatinine - blood Diabetes Diabetes mellitus Diabetes Mellitus, Type 2 Electrophoresis, Agar Gel Female Gene Frequency - genetics GENE POLYMORPHISM Genes Genetic Association Studies Genetic Predisposition to Disease - genetics Genotype Genotypes Glomerular filtration rate Glomerular Filtration Rate - genetics Glomerular Filtration Rate - physiology Humans IL‐4 IL‐6 Inflammation Interleukin 4 Interleukin 6 Interleukin-4 - genetics Interleukin-6 - genetics Kidney diseases Kidney transplantation Kidneys Male Middle Aged Polymerase chain reaction Polymorphism, Single Nucleotide - genetics Promoter Regions, Genetic - genetics Renal Insufficiency, Chronic - blood Renal Insufficiency, Chronic - genetics TYPE 2 DIABETES IL-4 TYPE 2 DIABETES CKD GENE POLYMORPHISM IL-6
ISSN:	0730-2312, 1097-4644, 1097-4644
Online Access:	Get full text
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