The biology of normal bone remodelling

During life, bone undergoes modelling and remodelling in order to grow or change shape. Bone modelling is the process by which bones change shape or size in response to physiologic influences or mechanical forces that are encountered by the skeleton, while bone remodelling takes place so that bone m...

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Vydáno v:	European journal of cancer care Ročník 26; číslo 6; s. e12740 - n/a
Hlavní autor:	Katsimbri, P.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England John Wiley & Sons, Inc 01.11.2017
Témata:	Adolescents Body composition Bone Development - physiology Bone growth Bone remodeling Bone Remodeling - physiology bone remodelling Bone Resorption Bones Calcification, Physiologic - physiology Cartilage Cartilage - growth & development Child development Children Homeostasis Human growth Humans Mineralization Modelling osteoblast Osteoblasts - physiology osteoclasts Osteoclasts - physiology osteocytes Osteocytes - physiology Osteogenesis Osteogenesis - physiology Skeleton Stress, Mechanical Teenagers bone remodelling osteoblast osteocytes osteoclasts
ISSN:	0961-5423, 1365-2354, 1365-2354
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Abstract	During life, bone undergoes modelling and remodelling in order to grow or change shape. Bone modelling is the process by which bones change shape or size in response to physiologic influences or mechanical forces that are encountered by the skeleton, while bone remodelling takes place so that bone may maintain its strength and mineral homeostasis. During early childhood, both bone modelling (the formation and shaping of bone) and bone remodelling (the replacement or renewal of old bone) occur. The predominant process in childhood is bone modelling, while in adulthood bone remodelling predominates. The exception to this is after a fracture when we see massive increases in bone formation. During childhood and adolescence growth occurs in the bones longitudinally and radially, while in the growth plates it occurs longitudinally, thus promoting growth in size. Cartilage first proliferates in the epiphyseal and metaphyseal areas of long bones before undergoing mineralisation to form new bone.
AbstractList	During life, bone undergoes modelling and remodelling in order to grow or change shape. Bone modelling is the process by which bones change shape or size in response to physiologic influences or mechanical forces that are encountered by the skeleton, while bone remodelling takes place so that bone may maintain its strength and mineral homeostasis. During early childhood, both bone modelling (the formation and shaping of bone) and bone remodelling (the replacement or renewal of old bone) occur. The predominant process in childhood is bone modelling, while in adulthood bone remodelling predominates. The exception to this is after a fracture when we see massive increases in bone formation. During childhood and adolescence growth occurs in the bones longitudinally and radially, while in the growth plates it occurs longitudinally, thus promoting growth in size. Cartilage first proliferates in the epiphyseal and metaphyseal areas of long bones before undergoing mineralisation to form new bone. During life, bone undergoes modelling and remodelling in order to grow or change shape. Bone modelling is the process by which bones change shape or size in response to physiologic influences or mechanical forces that are encountered by the skeleton, while bone remodelling takes place so that bone may maintain its strength and mineral homeostasis. During early childhood, both bone modelling (the formation and shaping of bone) and bone remodelling (the replacement or renewal of old bone) occur. The predominant process in childhood is bone modelling, while in adulthood bone remodelling predominates. The exception to this is after a fracture when we see massive increases in bone formation. During childhood and adolescence growth occurs in the bones longitudinally and radially, while in the growth plates it occurs longitudinally, thus promoting growth in size. Cartilage first proliferates in the epiphyseal and metaphyseal areas of long bones before undergoing mineralisation to form new bone.During life, bone undergoes modelling and remodelling in order to grow or change shape. Bone modelling is the process by which bones change shape or size in response to physiologic influences or mechanical forces that are encountered by the skeleton, while bone remodelling takes place so that bone may maintain its strength and mineral homeostasis. During early childhood, both bone modelling (the formation and shaping of bone) and bone remodelling (the replacement or renewal of old bone) occur. The predominant process in childhood is bone modelling, while in adulthood bone remodelling predominates. The exception to this is after a fracture when we see massive increases in bone formation. During childhood and adolescence growth occurs in the bones longitudinally and radially, while in the growth plates it occurs longitudinally, thus promoting growth in size. Cartilage first proliferates in the epiphyseal and metaphyseal areas of long bones before undergoing mineralisation to form new bone.
Author	Katsimbri, P.
Author_xml	– sequence: 1 givenname: P. surname: Katsimbri fullname: Katsimbri, P. email: pelkats@hol.gr organization: “Attikon” University Hospital
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/28786518$$D View this record in MEDLINE/PubMed
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Cites_doi	10.1038/ncb1647 10.1002/jcb.240590102 10.1007/s00198-010-1194-5 10.1016/S0021-9290(03)00126-X 10.1016/j.gene.2005.06.017 10.1016/j.devcel.2005.02.017 10.1006/cbir.1998.0338 10.1016/j.tem.2010.01.010 10.1016/j.molmed.2004.12.004 10.1196/annals.1402.068 10.1016/S8756-3282(98)00138-0 10.1359/jbmr.2000.15.1.2 10.1196/annals.1402.018 10.1002/jemt.10371 10.1038/nrg1122 10.1016/S8756-3282(02)00947-X 10.1038/sj.emboj.7601984 10.1371/journal.pone.0000179 10.1615/CritRevEukarGeneExpr.v19.i2.20 10.1210/me.2009-0066 10.1002/jcb.240550303 10.1126/science.1658941 10.1126/science.276.5310.266 10.1101/gad.1702708 10.1359/jbmr.2002.17.5.907 10.1016/j.bone.2007.12.224 10.1146/annurev.cellbio.042308.113308 10.2353/ajpath.2007.060834 10.1242/jcs.113.3.377 10.1111/j.1699-0463.1995.tb01089.x 10.1016/j.devcel.2005.03.016 10.1016/j.cmet.2009.12.007 10.1038/345442a0 10.1007/s11926-003-0071-z 10.1016/j.semcdb.2008.08.004 10.2353/ajpath.2009.080627 10.1016/S0092-8674(00)80257-3 10.1038/nature03398 10.1016/j.coph.2006.03.005
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Keywords	bone remodelling osteoblast osteocytes osteoclasts
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References	2009; 23 2010; 11 2002; 17 2009; 25 1990; 2S 1990; 345 1991; 254 2000; 113 1995; 59 2005; 357 2008; 19 2005; 434 1997; 276 1997; 89 2003; 36 1999; 23 2006; 6 2009; 174 1998; 23 2003; 32 2010; 21 2000; 15 2007; 170 2007; 1116 2005; 8 2008; 27 1994; 55 2007; 9 2003; 4 2003; 5 1995; 103 2008; 22 2007; 2 2008; 42 2003; 61 2009; 19 2005; 11 Guo (10.1111/ecc.12740-BIB0015\|ecc12740-cit-0015) 2010; 11 Cao (10.1111/ecc.12740-BIB0007\|ecc12740-cit-0007) 2005; 357 Hofbauer (10.1111/ecc.12740-BIB0016\|ecc12740-cit-0016) 2000; 15 Elefteriou (10.1111/ecc.12740-BIB0013\|ecc12740-cit-0013) 2005; 434 Karsenty (10.1111/ecc.12740-BIB0018\|ecc12740-cit-0018) 2009; 25 Rochefort (10.1111/ecc.12740-BIB0029\|ecc12740-cit-0029) 2010; 21 Lind (10.1111/ecc.12740-BIB0021\|ecc12740-cit-0021) 1995; 103 Kobayashi (10.1111/ecc.12740-BIB0019\|ecc12740-cit-0019) 2003; 32 Chamoux (10.1111/ecc.12740-BIB0008\|ecc12740-cit-0008) 2009; 23 Bonewald (10.1111/ecc.12740-BIB0004\|ecc12740-cit-0004) 2008; 42 Nesbitt (10.1111/ecc.12740-BIB0027\|ecc12740-cit-0027) 1997; 276 Yoshida (10.1111/ecc.12740-BIB0040\|ecc12740-cit-0040) 1990; 345 Coxon (10.1111/ecc.12740-BIB0010\|ecc12740-cit-0010) 2006; 6 Glass (10.1111/ecc.12740-BIB0014\|ecc12740-cit-0014) 2005; 8 Krum (10.1111/ecc.12740-BIB0020\|ecc12740-cit-0020) 2008; 27 Luxenburg (10.1111/ecc.12740-BIB0023\|ecc12740-cit-0023) 2007; 2 Manolagas (10.1111/ecc.12740-BIB0024\|ecc12740-cit-0024) 2010; 21 Vaananen (10.1111/ecc.12740-BIB0035\|ecc12740-cit-0035) 2000; 113 Weitzmann (10.1111/ecc.12740-BIB0038\|ecc12740-cit-0038) 2007; 1116 Rosen (10.1111/ecc.12740-BIB0030\|ecc12740-cit-0030) 2009; 19 Ducy (10.1111/ecc.12740-BIB0012\|ecc12740-cit-0012) 1997; 89 Teitelbaum (10.1111/ecc.12740-BIB0032\|ecc12740-cit-0032) 2007; 170 Mulari (10.1111/ecc.12740-BIB0026\|ecc12740-cit-0026) 2003; 61 Coxon (10.1111/ecc.12740-BIB0009\|ecc12740-cit-0009) 2008; 19 Wan (10.1111/ecc.12740-BIB0037\|ecc12740-cit-0037) 2008; 22 Bonewald (10.1111/ecc.12740-BIB0005\|ecc12740-cit-0005) 1990; 2S Parfitt (10.1111/ecc.12740-BIB0028\|ecc12740-cit-0028) 1994; 55 Andersen (10.1111/ecc.12740-BIB0001\|ecc12740-cit-0001) 2009; 174 Burger (10.1111/ecc.12740-BIB0006\|ecc12740-cit-0006) 2003; 36 Teitelbaum (10.1111/ecc.12740-BIB0033\|ecc12740-cit-0033) 1995; 59 Martin (10.1111/ecc.12740-BIB0025\|ecc12740-cit-0025) 2005; 11 Day (10.1111/ecc.12740-BIB0011\|ecc12740-cit-0011) 2005; 8 Yamaza (10.1111/ecc.12740-BIB0039\|ecc12740-cit-0039) 1998; 23 Teitelbaum (10.1111/ecc.12740-BIB0034\|ecc12740-cit-0034) 2003; 4 Bonewald (10.1111/ecc.12740-BIB0003\|ecc12740-cit-0003) 2007; 1116 Anderson (10.1111/ecc.12740-BIB0002\|ecc12740-cit-0002) 2003; 5 Locklin (10.1111/ecc.12740-BIB0022\|ecc12740-cit-0022) 1999; 23 Juppner (10.1111/ecc.12740-BIB0017\|ecc12740-cit-0017) 1991; 254 Verborgt (10.1111/ecc.12740-BIB0036\|ecc12740-cit-0036) 2002; 17 Takada (10.1111/ecc.12740-BIB0031\|ecc12740-cit-0031) 2007; 9
References_xml	– volume: 174 start-page: 239 year: 2009 end-page: 247 article-title: A physical mechanism for coupling bone resorption and formation in adult human bone publication-title: The American Journal of Pathology – volume: 434 start-page: 514 year: 2005 end-page: 520 article-title: Leptin regulation of bone resorption by the sympathetic nervous system and CART publication-title: Nature – volume: 61 start-page: 496 year: 2003 end-page: 503 article-title: Intracellular membrane trafficking in bone resorbing osteoclasts publication-title: Microscopy Research and Technique – volume: 32 start-page: 163 year: 2003 end-page: 169 article-title: Trabecular mini modeling in human iliac bone publication-title: Bone – volume: 89 start-page: 747 year: 1997 end-page: 754 article-title: Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation publication-title: Cell – volume: 17 start-page: 907 year: 2002 end-page: 914 article-title: Spatial distribution of Bax and Bcl‐2 in osteocytes after bone fatigue: complementary roles in bone remodeling regulation? publication-title: Journal of Bone and Mineral Research – volume: 345 start-page: 442 year: 1990 end-page: 444 article-title: The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene publication-title: Nature – volume: 19 start-page: 109 year: 2009 end-page: 124 article-title: Marrow fat and the bone microenvironment: Developmental, functional, and pathological implications publication-title: Critical Reviews in Eukaryotic Gene Expression – volume: 8 start-page: 739 year: 2005 end-page: 750 article-title: Wnt/beta‐catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis publication-title: Developmental Cell – volume: 276 start-page: 266 year: 1997 end-page: 273 article-title: Trafficking of matrix collagens through bone resorbing osteoclasts publication-title: Science – volume: 27 start-page: 535 year: 2008 end-page: 545 article-title: Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival publication-title: The EMBO Journal – volume: 1116 start-page: 281 year: 2007 end-page: 290 article-title: Osteocytes as dynamic multifunctional cells publication-title: Annals of the New York Academy of Sciences – volume: 23 start-page: 185 year: 1999 end-page: 194 article-title: Effects of TGFbeta and bFGF on the differentiation of human bone marrow stromal fibroblasts publication-title: Cell Biology International – volume: 21 start-page: 369 year: 2010 end-page: 374 article-title: What old means to bone publication-title: Trends in Endocrinology & Metabolism – volume: 42 start-page: 606 year: 2008 end-page: 615 article-title: Osteocytes, mechanosensing and Wnt signaling publication-title: Bone – volume: 59 start-page: 1 year: 1995 end-page: 10 article-title: Molecular mechanisms of bone resorption publication-title: Journal of Cellular Biochemistry – volume: 113 start-page: 377 year: 2000 end-page: 381 article-title: The cell biology of osteoclast function publication-title: Journal of Cell Science – volume: 5 start-page: 222 year: 2003 end-page: 226 article-title: Matrix vesicles and calcification publication-title: Current Rheumatology Reports – volume: 2 start-page: e179 year: 2007 article-title: The architecture of the adhesive apparatus of cultured osteoclasts: From podosome formation to sealing zone assembly publication-title: PLoS ONE – volume: 1116 start-page: 360 year: 2007 end-page: 375 article-title: T cells: Unexpected players in the bone loss induced by estrogen deficiency and in basal bone homeostasis publication-title: Annals of the New York Academy of Sciences – volume: 11 start-page: 76 year: 2005 end-page: 81 article-title: Osteoclast‐derived activity in the coupling of bone formation to resorption publication-title: Trends in Molecular Medicine – volume: 357 start-page: 1 year: 2005 end-page: 8 article-title: The BMP signalling and in vivo bone formation publication-title: Gene – volume: 21 start-page: 1457 year: 2010 end-page: 1469 article-title: Osteocyte: The unrecognised side of bone tissue publication-title: Osteoporosis International – volume: 254 start-page: 1024 year: 1991 end-page: 1026 article-title: A G protein‐linked receptor for parathyroid hormone and parathyroid hormone‐related peptide publication-title: Science – volume: 36 start-page: 1452 year: 2003 end-page: 1459 article-title: Strain‐derived canalicular fluid flow regulates osteoclast activity in a remodeling osteon: A proposal publication-title: Journal of Biomechanics – volume: 11 start-page: 161 year: 2010 end-page: 171 article-title: Suppression of Wnt signaling by Dkk1 attenuates PTH‐mediated stromal cell response and new bone formation publication-title: Cell Metabolism – volume: 103 start-page: 140 year: 1995 end-page: 146 article-title: Chemotaxis of human osteoblasts. Effects of osteotropic growth factors publication-title: APMIS – volume: 22 start-page: 2968 year: 2008 end-page: 2979 article-title: Parathyroid hormone signaling through low‐density lipoprotein related protein 6 publication-title: Genes & Development – volume: 25 start-page: 629 year: 2009 end-page: 648 article-title: Genetic control of bone formation publication-title: Annual Review of Cell and Developmental – volume: 19 start-page: 424 year: 2008 end-page: 433 article-title: Vesicular trafficking in osteoclasts publication-title: Seminars in Cell & Developmental Biology – volume: 9 start-page: 1273 year: 2007 end-page: 1285 article-title: A histone lysine methyltransferase activated by non‐canonical Wnt signalling suppresses PPAR‐gamma transactivation publication-title: Nature Cell Biology – volume: 15 start-page: 2 year: 2000 end-page: 12 article-title: The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption publication-title: Journal of Bone and Mineral Research – volume: 55 start-page: 273 year: 1994 end-page: 276 article-title: Osteonal and hemiosteonal remodeling: The spatial and temporal framework for signal traffic in adult bone publication-title: Journal of Cellular Biochemistry – volume: 23 start-page: 1668 year: 2009 end-page: 1680 article-title: The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts publication-title: Molecular Endocrinology – volume: 4 start-page: 638 year: 2003 end-page: 649 article-title: Genetic regulation of osteoclast development and function publication-title: Nature Reviews Genetics – volume: 8 start-page: 751 year: 2005 end-page: 764 article-title: Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation publication-title: Developmental Cell – volume: 6 start-page: 307 year: 2006 end-page: 312 article-title: Recent advances in understanding the mechanism of action of bisphosphonates publication-title: Current Opinion in Pharmacology – volume: 2S start-page: 35 year: 1990 end-page: 40 article-title: Role of transforming growth factor beta in bone remodeling publication-title: Clinical Orthopaedics and Related Research – volume: 170 start-page: 427 year: 2007 end-page: 435 article-title: Osteoclasts: what do they do and how do they do it? publication-title: The American Journal of Pathology – volume: 23 start-page: 499 year: 1998 end-page: 509 article-title: Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femur publication-title: Bone – volume: 9 start-page: 1273 year: 2007 ident: 10.1111/ecc.12740-BIB0031\|ecc12740-cit-0031 article-title: A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation publication-title: Nature Cell Biology doi: 10.1038/ncb1647 – volume: 59 start-page: 1 year: 1995 ident: 10.1111/ecc.12740-BIB0033\|ecc12740-cit-0033 article-title: Molecular mechanisms of bone resorption publication-title: Journal of Cellular Biochemistry doi: 10.1002/jcb.240590102 – volume: 21 start-page: 1457 year: 2010 ident: 10.1111/ecc.12740-BIB0029\|ecc12740-cit-0029 article-title: Osteocyte: The unrecognised side of bone tissue publication-title: Osteoporosis International doi: 10.1007/s00198-010-1194-5 – volume: 36 start-page: 1452 year: 2003 ident: 10.1111/ecc.12740-BIB0006\|ecc12740-cit-0006 article-title: Strain-derived canalicular fluid flow regulates osteoclast activity in a remodeling osteon: A proposal publication-title: Journal of Biomechanics doi: 10.1016/S0021-9290(03)00126-X – volume: 357 start-page: 1 year: 2005 ident: 10.1111/ecc.12740-BIB0007\|ecc12740-cit-0007 article-title: The BMP signalling and in vivo bone formation publication-title: Gene doi: 10.1016/j.gene.2005.06.017 – volume: 8 start-page: 751 year: 2005 ident: 10.1111/ecc.12740-BIB0014\|ecc12740-cit-0014 article-title: Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation publication-title: Developmental Cell doi: 10.1016/j.devcel.2005.02.017 – volume: 23 start-page: 185 year: 1999 ident: 10.1111/ecc.12740-BIB0022\|ecc12740-cit-0022 article-title: Effects of TGFbeta and bFGF on the differentiation of human bone marrow stromal fibroblasts publication-title: Cell Biology International doi: 10.1006/cbir.1998.0338 – volume: 21 start-page: 369 year: 2010 ident: 10.1111/ecc.12740-BIB0024\|ecc12740-cit-0024 article-title: What old means to bone publication-title: Trends in Endocrinology & Metabolism doi: 10.1016/j.tem.2010.01.010 – volume: 11 start-page: 76 year: 2005 ident: 10.1111/ecc.12740-BIB0025\|ecc12740-cit-0025 article-title: Osteoclast-derived activity in the coupling of bone formation to resorption publication-title: Trends in Molecular Medicine doi: 10.1016/j.molmed.2004.12.004 – volume: 1116 start-page: 360 year: 2007 ident: 10.1111/ecc.12740-BIB0038\|ecc12740-cit-0038 article-title: T cells: Unexpected players in the bone loss induced by estrogen deficiency and in basal bone homeostasis publication-title: Annals of the New York Academy of Sciences doi: 10.1196/annals.1402.068 – volume: 23 start-page: 499 year: 1998 ident: 10.1111/ecc.12740-BIB0039\|ecc12740-cit-0039 article-title: Study of immunoelectron microscopic localization of cathepsin K in osteoclasts and other bone cells in the mouse femur publication-title: Bone doi: 10.1016/S8756-3282(98)00138-0 – volume: 15 start-page: 2 year: 2000 ident: 10.1111/ecc.12740-BIB0016\|ecc12740-cit-0016 article-title: The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption publication-title: Journal of Bone and Mineral Research doi: 10.1359/jbmr.2000.15.1.2 – volume: 2S start-page: 35 year: 1990 ident: 10.1111/ecc.12740-BIB0005\|ecc12740-cit-0005 article-title: Role of transforming growth factor beta in bone remodeling publication-title: Clinical Orthopaedics and Related Research – volume: 1116 start-page: 281 year: 2007 ident: 10.1111/ecc.12740-BIB0003\|ecc12740-cit-0003 article-title: Osteocytes as dynamic multifunctional cells publication-title: Annals of the New York Academy of Sciences doi: 10.1196/annals.1402.018 – volume: 61 start-page: 496 year: 2003 ident: 10.1111/ecc.12740-BIB0026\|ecc12740-cit-0026 article-title: Intracellular membrane trafficking in bone resorbing osteoclasts publication-title: Microscopy Research and Technique doi: 10.1002/jemt.10371 – volume: 4 start-page: 638 year: 2003 ident: 10.1111/ecc.12740-BIB0034\|ecc12740-cit-0034 article-title: Genetic regulation of osteoclast development and function publication-title: Nature Reviews Genetics doi: 10.1038/nrg1122 – volume: 32 start-page: 163 year: 2003 ident: 10.1111/ecc.12740-BIB0019\|ecc12740-cit-0019 article-title: Trabecular mini modeling in human iliac bone publication-title: Bone doi: 10.1016/S8756-3282(02)00947-X – volume: 27 start-page: 535 year: 2008 ident: 10.1111/ecc.12740-BIB0020\|ecc12740-cit-0020 article-title: Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival publication-title: The EMBO Journal doi: 10.1038/sj.emboj.7601984 – volume: 2 start-page: e179 year: 2007 ident: 10.1111/ecc.12740-BIB0023\|ecc12740-cit-0023 article-title: The architecture of the adhesive apparatus of cultured osteoclasts: From podosome formation to sealing zone assembly publication-title: PLoS ONE doi: 10.1371/journal.pone.0000179 – volume: 19 start-page: 109 year: 2009 ident: 10.1111/ecc.12740-BIB0030\|ecc12740-cit-0030 article-title: Marrow fat and the bone microenvironment: Developmental, functional, and pathological implications publication-title: Critical Reviews in Eukaryotic Gene Expression doi: 10.1615/CritRevEukarGeneExpr.v19.i2.20 – volume: 23 start-page: 1668 year: 2009 ident: 10.1111/ecc.12740-BIB0008\|ecc12740-cit-0008 article-title: The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts publication-title: Molecular Endocrinology doi: 10.1210/me.2009-0066 – volume: 55 start-page: 273 year: 1994 ident: 10.1111/ecc.12740-BIB0028\|ecc12740-cit-0028 article-title: Osteonal and hemiosteonal remodeling: The spatial and temporal framework for signal traffic in adult bone publication-title: Journal of Cellular Biochemistry doi: 10.1002/jcb.240550303 – volume: 254 start-page: 1024 year: 1991 ident: 10.1111/ecc.12740-BIB0017\|ecc12740-cit-0017 article-title: A G protein-linked receptor for parathyroid hormone and parathyroid hormone-related peptide publication-title: Science doi: 10.1126/science.1658941 – volume: 276 start-page: 266 year: 1997 ident: 10.1111/ecc.12740-BIB0027\|ecc12740-cit-0027 article-title: Trafficking of matrix collagens through bone resorbing osteoclasts publication-title: Science doi: 10.1126/science.276.5310.266 – volume: 22 start-page: 2968 year: 2008 ident: 10.1111/ecc.12740-BIB0037\|ecc12740-cit-0037 article-title: Parathyroid hormone signaling through low-density lipoprotein related protein 6 publication-title: Genes & Development doi: 10.1101/gad.1702708 – volume: 17 start-page: 907 year: 2002 ident: 10.1111/ecc.12740-BIB0036\|ecc12740-cit-0036 article-title: Spatial distribution of Bax and Bcl-2 in osteocytes after bone fatigue: complementary roles in bone remodeling regulation? publication-title: Journal of Bone and Mineral Research doi: 10.1359/jbmr.2002.17.5.907 – volume: 42 start-page: 606 year: 2008 ident: 10.1111/ecc.12740-BIB0004\|ecc12740-cit-0004 article-title: Osteocytes, mechanosensing and Wnt signaling publication-title: Bone doi: 10.1016/j.bone.2007.12.224 – volume: 25 start-page: 629 year: 2009 ident: 10.1111/ecc.12740-BIB0018\|ecc12740-cit-0018 article-title: Genetic control of bone formation publication-title: Annual Review of Cell and Developmental doi: 10.1146/annurev.cellbio.042308.113308 – volume: 170 start-page: 427 year: 2007 ident: 10.1111/ecc.12740-BIB0032\|ecc12740-cit-0032 article-title: Osteoclasts: what do they do and how do they do it? publication-title: The American Journal of Pathology doi: 10.2353/ajpath.2007.060834 – volume: 113 start-page: 377 year: 2000 ident: 10.1111/ecc.12740-BIB0035\|ecc12740-cit-0035 article-title: The cell biology of osteoclast function publication-title: Journal of Cell Science doi: 10.1242/jcs.113.3.377 – volume: 103 start-page: 140 year: 1995 ident: 10.1111/ecc.12740-BIB0021\|ecc12740-cit-0021 article-title: Chemotaxis of human osteoblasts. Effects of osteotropic growth factors publication-title: APMIS doi: 10.1111/j.1699-0463.1995.tb01089.x – volume: 8 start-page: 739 year: 2005 ident: 10.1111/ecc.12740-BIB0011\|ecc12740-cit-0011 article-title: Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis publication-title: Developmental Cell doi: 10.1016/j.devcel.2005.03.016 – volume: 11 start-page: 161 year: 2010 ident: 10.1111/ecc.12740-BIB0015\|ecc12740-cit-0015 article-title: Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation publication-title: Cell Metabolism doi: 10.1016/j.cmet.2009.12.007 – volume: 345 start-page: 442 year: 1990 ident: 10.1111/ecc.12740-BIB0040\|ecc12740-cit-0040 article-title: The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene publication-title: Nature doi: 10.1038/345442a0 – volume: 5 start-page: 222 year: 2003 ident: 10.1111/ecc.12740-BIB0002\|ecc12740-cit-0002 article-title: Matrix vesicles and calcification publication-title: Current Rheumatology Reports doi: 10.1007/s11926-003-0071-z – volume: 19 start-page: 424 year: 2008 ident: 10.1111/ecc.12740-BIB0009\|ecc12740-cit-0009 article-title: Vesicular trafficking in osteoclasts publication-title: Seminars in Cell & Developmental Biology doi: 10.1016/j.semcdb.2008.08.004 – volume: 174 start-page: 239 year: 2009 ident: 10.1111/ecc.12740-BIB0001\|ecc12740-cit-0001 article-title: A physical mechanism for coupling bone resorption and formation in adult human bone publication-title: The American Journal of Pathology doi: 10.2353/ajpath.2009.080627 – volume: 89 start-page: 747 year: 1997 ident: 10.1111/ecc.12740-BIB0012\|ecc12740-cit-0012 article-title: Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation publication-title: Cell doi: 10.1016/S0092-8674(00)80257-3 – volume: 434 start-page: 514 year: 2005 ident: 10.1111/ecc.12740-BIB0013\|ecc12740-cit-0013 article-title: Leptin regulation of bone resorption by the sympathetic nervous system and CART publication-title: Nature doi: 10.1038/nature03398 – volume: 6 start-page: 307 year: 2006 ident: 10.1111/ecc.12740-BIB0010\|ecc12740-cit-0010 article-title: Recent advances in understanding the mechanism of action of bisphosphonates publication-title: Current Opinion in Pharmacology doi: 10.1016/j.coph.2006.03.005
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SubjectTerms	Adolescents Body composition Bone Development - physiology Bone growth Bone remodeling Bone Remodeling - physiology bone remodelling Bone Resorption Bones Calcification, Physiologic - physiology Cartilage Cartilage - growth & development Child development Children Homeostasis Human growth Humans Mineralization Modelling osteoblast Osteoblasts - physiology osteoclasts Osteoclasts - physiology osteocytes Osteocytes - physiology Osteogenesis Osteogenesis - physiology Skeleton Stress, Mechanical Teenagers
Title	The biology of normal bone remodelling
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