Assessing the Gold Standard — Lessons from the History of RCTs

Over the past 70 years, randomized, controlled trials (RCTs) have reshaped medical knowledge and practice. Popularized by mid-20th-century clinical researchers and statisticians aiming to reduce bias and enhance the accuracy of clinical experimentation, RCTs have often functioned well in that role....

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Bibliographic Details
Published in:The New England journal of medicine Vol. 374; no. 22; pp. 2175 - 2181
Main Authors: Bothwell, Laura E, Greene, Jeremy A, Podolsky, Scott H, Jones, David S
Format: Journal Article
Language:English
Published: United States Massachusetts Medical Society 02.06.2016
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ISSN:0028-4793, 1533-4406
Online Access:Get full text
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