Atherosclerotic Plaque Healing

Atherosclerotic plaque rupture and erosion result in acute coronary syndromes. Plaque healing after initial disruption has been less extensively studied. Reviewed are mechanisms and phenotypic features of plaque healing, its role in clinical events, and therapeutic implications.

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Veröffentlicht in:The New England journal of medicine Jg. 383; H. 9; S. 846 - 857
Hauptverfasser: Vergallo, Rocco, Crea, Filippo
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Massachusetts Medical Society 27.08.2020
Schlagworte:
Acute Coronary Syndrome - etiology
Acute coronary syndromes
Arteriosclerosis
Atherosclerosis
Blood clots
Blood platelets
Collagen
Coronary Thrombosis - complications
Coronary Thrombosis - physiopathology
Extracellular matrix
Growth factors
Humans
Inflammation - physiopathology
Lipids
Magnetic resonance imaging
Plaque, Atherosclerotic - diagnostic imaging
Plaque, Atherosclerotic - pathology
Plaque, Atherosclerotic - physiopathology
Rupture, Spontaneous - complications
Rupture, Spontaneous - physiopathology
Thrombosis
Tomography, Optical Coherence
ISSN:0028-4793, 1533-4406, 1533-4406
Online-Zugang:Volltext
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Zusammenfassung:Atherosclerotic plaque rupture and erosion result in acute coronary syndromes. Plaque healing after initial disruption has been less extensively studied. Reviewed are mechanisms and phenotypic features of plaque healing, its role in clinical events, and therapeutic implications.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ObjectType-Review-3
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMra2000317