Transcriptomes of human primary skin fibroblasts of healthy individuals reveal age‐associated mRNAs and long noncoding RNAs

Changes in the transcriptomes of human tissues with advancing age are poorly cataloged. Here, we sought to identify the coding and long noncoding RNAs present in cultured primary skin fibroblasts collected from 82 healthy individuals across a wide age spectrum (22–89 years old) who participated in t...

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Bibliographic Details
Published in:	Aging cell Vol. 22; no. 11; p. e13915
Main Authors:	Tsitsipatis, Dimitrios, Martindale, Jennifer L., Mazan‐Mamczarz, Krystyna, Herman, Allison B., Piao, Yulan, Banskota, Nirad, Yang, Jen‐Hao, Cui, Linna, Anerillas, Carlos, Chang, Ming‐Wen, Kaileh, Mary, Munk, Rachel, Yang, Xiaoling, Ubaida‐Mohien, Ceereena, Chia, Chee W., Karikkineth, Ajoy C., Zukley, Linda, D'Agostino, Jarod, Abdelmohsen, Kotb, Basisty, Nathan, De, Supriyo, Ferrucci, Luigi, Gorospe, Myriam
Format:	Journal Article
Language:	English
Published:	England John Wiley & Sons, Inc 01.11.2023
Subjects:	Adult Age Aged Aged, 80 and over Aging Biomarkers - metabolism Biopsy Cytokines Dehydrogenases Epigenetics Extracellular matrix Fibroblasts Fibroblasts - metabolism Gene Expression Profiling Gene set enrichment analysis Growth factors Humans Hyaluronic acid Kinases Males Middle Aged Non-coding RNA Proteins Regression analysis RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism RNA-binding protein Skin Therapeutic targets Transcription factors Transcriptome - genetics Transcriptomes White people Young Adult messenger RNAs long noncoding RNAs aging human dermal fibroblasts circular RNAs transcriptome
ISSN:	1474-9718, 1474-9726, 1474-9726
Online Access:	Get full text
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