The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer

Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activa...

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Veröffentlicht in:	International journal of cancer Jg. 157; H. 12; S. 2434 - 2446
Hauptverfasser:	Liu, Wen, Gupta, Sahil, Gupta, Sanjeev
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Hoboken, USA John Wiley & Sons, Inc 15.12.2025 Wiley Subscription Services, Inc
Schlagworte:	Animals Antineoplastic Agents, Hormonal - pharmacology Antineoplastic Agents, Hormonal - therapeutic use Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - pathology Cell fate Drug Resistance, Neoplasm - genetics endocrine resistance Endocrine therapy Endoplasmic reticulum Endoplasmic Reticulum Stress - genetics Estrogen receptors Female Gene Expression Regulation, Neoplastic Humans long noncoding RNA Microenvironments Non-coding RNA Patients Protein folding RNA, Long Noncoding - genetics Signal Transduction unfolded protein response Unfolded Protein Response - genetics long noncoding RNA unfolded protein response breast cancer endocrine resistance
ISSN:	0020-7136, 1097-0215, 1097-0215
Online-Zugang:	Volltext
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