PARP15 Is a Susceptibility Locus for Clarkson Disease (Monoclonal Gammopathy-Associated Systemic Capillary Leak Syndrome)

Vascular leakage is a deadly complication of severe infections, ranging from bacterial sepsis to malaria. Worldwide, septicemia is among the top 10 causes of lethality because of the shock and multiorgan dysfunction that arise from the host vascular response. In the monoclonal gammopathy-associated...

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Bibliographic Details
Published in:	Arteriosclerosis, thrombosis, and vascular biology Vol. 44; no. 12; p. 2628
Main Authors:	Chan, Eunice C, Ablooglu, Ararat J, Ghosh, Chandra C, Desai, Abhishek, Schaible, Niccole, Chen, Xiuying, Zhao, Ming, Olano, M Renee, Ganesan, Sundar, Lack, Justin B, Krishnan, Ramaswamy, Parikh, Samir M, Druey, Kirk M
Format:	Journal Article
Language:	English
Published:	United States 01.12.2024
Subjects:	Animals Capillary Leak Syndrome - genetics Capillary Permeability Cells, Cultured Disease Models, Animal Endothelial Cells - enzymology Endothelial Cells - metabolism Female Genetic Predisposition to Disease Humans Loss of Function Mutation Male Mice Mice, Inbred C57BL Mice, Knockout p38 Mitogen-Activated Protein Kinases - genetics p38 Mitogen-Activated Protein Kinases - metabolism Paraproteinemias - complications Paraproteinemias - genetics Phenotype Poly(ADP-ribose) Polymerases - genetics Poly(ADP-ribose) Polymerases - metabolism diphtheria toxin influenza, human endothelial cells histamine adenosine diphosphate ribose
ISSN:	1524-4636, 1524-4636
Online Access:	Get more information
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