Intranasal Delivery of BACE1 siRNA and Rapamycin by Dual Targets Modified Nanoparticles for Alzheimer's Disease Therapy

Alzheimer's disease (AD), as a progressive and irreversible brain disorder, remains the most universal neurodegenerative disease. No effective therapeutic methods are established yet due to the hindrance of the blood‐brain barrier (BBB) and the complex pathological condition of AD.  Therefore,...

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Vydané v:	Small (Weinheim an der Bergstrasse, Germany) Ročník 18; číslo 30; s. e2203182 - n/a
Hlavní autori:	Yang, Xiaotong, Yang, Wenqin, Xia, Xue, Lei, Ting, Yang, Zhihang, Jia, Wenfeng, Zhou, Yang, Cheng, Guo, Gao, Huile
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Weinheim Wiley Subscription Services, Inc 01.07.2022
Predmet:	Agglomeration Aleuria aurantia lectin Alzheimer's disease amyloid‐β autophagy Binding Brain Cognition intranasal administration Nanoparticles Nanotechnology Peptides Rapamycin Toxicity
ISSN:	1613-6810, 1613-6829, 1613-6829
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