Block Search Stochastic Simulation Algorithm (BlSSSA): A Fast Stochastic Simulation Algorithm for Modeling Large Biochemical Networks

Stochastic simulation algorithms are extensively used for exploring stochastic behavior of biochemical pathways/networks. Computational cost of these algorithms is high in simulating real biochemical systems due to their large size, complex structure and stiffness. In order to reduce the computation...

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Bibliographic Details
Published in:	IEEE/ACM transactions on computational biology and bioinformatics Vol. 19; no. 4; pp. 2111 - 2123
Main Authors:	Ghosh, Debraj, De, Rajat K.
Format:	Journal Article
Language:	English
Published:	United States IEEE 01.07.2022 The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
Subjects:	1,3-Butadiene Algorithms B cell receptor signaling network Biochemistry Biological system modeling Colloidal aggregation network and stochastic modeling Computational efficiency Computational modeling Computer applications Computing costs Data structures Fc receptors FceRI signaling network Gillespie algorithm Indexes Mathematical model Networks Oxidation Signaling Simulation Statistics Stiff network Stiffness Stochastic processes Stochasticity
ISSN:	1545-5963, 1557-9964, 1557-9964
Online Access:	Get full text
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