Penalized spline estimation in varying coefficient models with censored data

We consider P-spline smoothing in a varying coefficient regression model when the response is subject to random right censoring. We introduce two data transformation approaches to construct a synthetic response vector that is used in a penalized least squares optimization problem. We prove the consi...

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Veröffentlicht in:Test (Madrid, Spain) Jg. 27; H. 4; S. 871 - 895
Hauptverfasser: Hendrickx, K., Janssen, P., Verhasselt, A.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Berlin/Heidelberg Springer Berlin Heidelberg 01.12.2018
Springer Nature B.V
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ISSN:1133-0686, 1863-8260
Online-Zugang:Volltext
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Zusammenfassung:We consider P-spline smoothing in a varying coefficient regression model when the response is subject to random right censoring. We introduce two data transformation approaches to construct a synthetic response vector that is used in a penalized least squares optimization problem. We prove the consistency and asymptotic normality of the P-spline estimators for a diverging number of knots and show by simulation studies and real data examples that the combination of a data transformation for censored observations with P-spline smoothing leads to good estimators of the varying coefficient functions.
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ISSN:1133-0686
1863-8260
DOI:10.1007/s11749-017-0574-y