A micronutrient with major effects on cancer cell viability

Selenium is a micronutrient essential for the generation of selenoproteins, which function predominantly by detoxifying cellular reactive oxygen species. In this issue, Carlisle et al. describe a novel mechanism whereby perturbing selenium utilization via inhibition of SEPHS2, a component of the sel...

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Vydané v:	Nature metabolism Ročník 2; číslo 7; s. 564 - 565
Hlavní autori:	Kapara, Anastasia, Vannini, Alessandro, Peck, Barrie
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London Nature Publishing Group UK 01.07.2020 Nature Publishing Group
Predmet:	631/443/319 631/67/1059 631/67/1347 631/67/2327 Ablation Biomarkers Biomedical and Life Sciences Breast cancer Cell death Cell viability CRISPR Ferroptosis Genomes Glutathione Kinases Life Sciences Localization Metabolism Micronutrients News & Views news-and-views Proteins Reactive oxygen species RNA polymerase Selenide Selenium Selenocysteine Selenoproteins Transfer RNA
ISSN:	2522-5812, 2522-5812
On-line prístup:	Získať plný text
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