Contrast‐Induced Encephalopathy After Neurointerventional Procedures: A Series of Three Cases

Introduction: Contrast‐induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions. The phenomenon is well‐described following coronary angiography but reports following endovascular neurointerventional procedures are sparse....

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Veröffentlicht in:	Case reports in neurological medicine Jg. 2025; H. 1; S. 4384841
Hauptverfasser:	Wang, Kaiying, Goh, Rudy, El-Masri, Shaddy, Bacchi, Stephen, Patel, Sandy, Jannes, Jim, Kleinig, Timothy
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States John Wiley & Sons, Inc 01.01.2025 Wiley
Schlagworte:	Angiography Complications and side effects Encephalopathy Levetiracetam Medical imaging equipment Medical research Medicine, Experimental Pantoprazole Tenecteplase Ticagrelor Tirofiban Australia computed tomography case report differential diagnosis contrast-induced encephalopathy radiology stroke management
ISSN:	2090-6668, 2090-6676
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Abstract	Introduction: Contrast‐induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions. The phenomenon is well‐described following coronary angiography but reports following endovascular neurointerventional procedures are sparse. This study aims to describe the clinical presentation, treatment and outcome of CIE in a tertiary metropolitan hospital in South Australia. Methods: This study describes a case series of 3 patients diagnosed with CIE following cerebral angiography within a 1‐year period in a tertiary hospital. Results: All patients developed slowly progressive (and/or new) focal or global neurological deficits 2–7 h postprocedure and exhibited characteristic neuroimaging findings. Two of three patients made an excellent recovery with supportive care, improving after 48–72 h, although one died due to the severity of her associated stroke. Conclusion: CIE should be suspected in patients presenting with acute neurological deterioration following cerebral angiography. Supportive care may lead to full recovery. Multicentre prospective cohort studies are required to better define associations, diagnostic criteria and interventions to prevent and/or treat this condition.
AbstractList	Introduction: Contrast-induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions. The phenomenon is well-described following coronary angiography but reports following endovascular neurointerventional procedures are sparse. This study aims to describe the clinical presentation, treatment and outcome of CIE in a tertiary metropolitan hospital in South Australia. Methods: This study describes a case series of 3 patients diagnosed with CIE following cerebral angiography within a 1-year period in a tertiary hospital. Results: All patients developed slowly progressive (and/or new) focal or global neurological deficits 2-7h postprocedure and exhibited characteristic neuroimaging findings. Two of three patients made an excellent recovery with supportive care, improving after 48-72h, although one died due to the severity of her associated stroke. Conclusion: CIE should be suspected in patients presenting with acute neurological deterioration following cerebral angiography. Supportive care may lead to full recovery. Multicentre prospective cohort studies are required to better define associations, diagnostic criteria and interventions to prevent and/or treat this condition. Conclusion: CIE should be suspected in patients presenting with acute neurological deterioration following cerebral angiography. Supportive care may lead to full recovery. Multicentre prospective cohort studies are required to better define associations, diagnostic criteria and interventions to prevent and/or treat this condition. Contrast-induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions. The phenomenon is well-described following coronary angiography but reports following endovascular neurointerventional procedures are sparse. This study aims to describe the clinical presentation, treatment and outcome of CIE in a tertiary metropolitan hospital in South Australia. This study describes a case series of 3 patients diagnosed with CIE following cerebral angiography within a 1-year period in a tertiary hospital. All patients developed slowly progressive (and/or new) focal or global neurological deficits 2-7 h postprocedure and exhibited characteristic neuroimaging findings. Two of three patients made an excellent recovery with supportive care, improving after 48-72 h, although one died due to the severity of her associated stroke. CIE should be suspected in patients presenting with acute neurological deterioration following cerebral angiography. Supportive care may lead to full recovery. Multicentre prospective cohort studies are required to better define associations, diagnostic criteria and interventions to prevent and/or treat this condition. Introduction: Contrast-induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions. The phenomenon is well-described following coronary angiography but reports following endovascular neurointerventional procedures are sparse. This study aims to describe the clinical presentation, treatment and outcome of CIE in a tertiary metropolitan hospital in South Australia. Methods: This study describes a case series of 3 patients diagnosed with CIE following cerebral angiography within a 1-year period in a tertiary hospital. Results: All patients developed slowly progressive (and/or new) focal or global neurological deficits 2-7 h postprocedure and exhibited characteristic neuroimaging findings. Two of three patients made an excellent recovery with supportive care, improving after 48-72 h, although one died due to the severity of her associated stroke. Conclusion: CIE should be suspected in patients presenting with acute neurological deterioration following cerebral angiography. Supportive care may lead to full recovery. Multicentre prospective cohort studies are required to better define associations, diagnostic criteria and interventions to prevent and/or treat this condition.Introduction: Contrast-induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions. The phenomenon is well-described following coronary angiography but reports following endovascular neurointerventional procedures are sparse. This study aims to describe the clinical presentation, treatment and outcome of CIE in a tertiary metropolitan hospital in South Australia. Methods: This study describes a case series of 3 patients diagnosed with CIE following cerebral angiography within a 1-year period in a tertiary hospital. Results: All patients developed slowly progressive (and/or new) focal or global neurological deficits 2-7 h postprocedure and exhibited characteristic neuroimaging findings. Two of three patients made an excellent recovery with supportive care, improving after 48-72 h, although one died due to the severity of her associated stroke. Conclusion: CIE should be suspected in patients presenting with acute neurological deterioration following cerebral angiography. Supportive care may lead to full recovery. Multicentre prospective cohort studies are required to better define associations, diagnostic criteria and interventions to prevent and/or treat this condition. Introduction: Contrast‐induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions. The phenomenon is well‐described following coronary angiography but reports following endovascular neurointerventional procedures are sparse. This study aims to describe the clinical presentation, treatment and outcome of CIE in a tertiary metropolitan hospital in South Australia. Methods: This study describes a case series of 3 patients diagnosed with CIE following cerebral angiography within a 1‐year period in a tertiary hospital. Results: All patients developed slowly progressive (and/or new) focal or global neurological deficits 2–7 h postprocedure and exhibited characteristic neuroimaging findings. Two of three patients made an excellent recovery with supportive care, improving after 48–72 h, although one died due to the severity of her associated stroke. Conclusion: CIE should be suspected in patients presenting with acute neurological deterioration following cerebral angiography. Supportive care may lead to full recovery. Multicentre prospective cohort studies are required to better define associations, diagnostic criteria and interventions to prevent and/or treat this condition.
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Author	Jannes, Jim Bacchi, Stephen Goh, Rudy Patel, Sandy El-Masri, Shaddy Kleinig, Timothy Wang, Kaiying
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Copyright	Copyright © 2025 Kaiying Wang et al. Case Reports in Neurological Medicine published by John Wiley & Sons Ltd. COPYRIGHT 2025 John Wiley & Sons, Inc.
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Snippet	Introduction: Contrast‐induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions.... Contrast-induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions. The phenomenon... Introduction: Contrast-induced encephalopathy (CIE) is a rare complication that may occur following contrast administration during endovascular interventions.... Conclusion: CIE should be suspected in patients presenting with acute neurological deterioration following cerebral angiography. Supportive care may lead to...
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SubjectTerms	Angiography Complications and side effects Encephalopathy Levetiracetam Medical imaging equipment Medical research Medicine, Experimental Pantoprazole Tenecteplase Ticagrelor Tirofiban
Title	Contrast‐Induced Encephalopathy After Neurointerventional Procedures: A Series of Three Cases
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